Pyrrolidines

Organic heterocyclic compounds that consist of a five-membered ring with four carbon atoms and one nitrogen atom that form a cyclic secondary amine.

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1,486 – 1,500 of 6,304 results

1,486

Medchemexpress LLC 1-Boc-3-aminopyrrolidine | 186550-13-0 | 99.9% | 186.25 | 10 G

1-Boc-3-Aminopyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is intended for research use only.

Biochemical reagent for life science research
Suitable as a biological material
Suitable as an organic compound
Not for sale to patients

Pricing & Availability

1,487

Medchemexpress LLC Boc-NH-PEG6-amine | 1091627-77-8 | 97.0% | C19H40N2O8 | 250 MG

Boc-NH-PEG6-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are molecules that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Utilized in the synthesis of PROTACs
Contains two different ligands connected by a linker
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins

Pricing & Availability

1,488

Medchemexpress LLC HS-PEG6-CH2CH2-Boc | 1818294-40-4 | >98.0% | C19H38O8S | 10MG

HS-PEG6-CH2CH2-Boc is a polyethylene glycol (PEG)-based PROTAC linker featuring a protected thiol and a tert-butyloxycarbonyl (Boc)-protected terminus. It is supplied at high purity (>98%), has molecular formula C19H38O8S and molecular weight 426.57 g·mol⁻¹, and is soluble in DMSO (10 mM), making it suitable for use in small-molecule linker assembly.

Provides a flexible, hydrophilic spacer for connecting ligands in PROTAC synthesis.
Contains a protected thiol for selective deprotection and conjugation.
Features a Boc-protected terminus compatible with standard amine deprotection chemistry.
High reported purity supports reliable synthetic outcomes.
Soluble in DMSO at 10 mM for convenient handling in solution-phase reactions.

Pricing & Availability

1,489

Medchemexpress LLC Boc-NH-PEG8-C2-Br | 2688072-12-8 | 99.8% | 576.52 | 25 MG

Boc-NH-PEG8-C2-Br is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is intended for research use only.

Molecular weight: 576.52
Chemical formula: C23H46BrNO10
Appearance: Colorless to light yellow liquid
Purity (HPLC): 99.8%
Consistent with structure by 1H NMR and MS
Applicable in cancer and cancer targeted therapy research

Pricing & Availability

1,490

Medchemexpress LLC Tert-butyl 4-(4-aminobutyl)piperazine-1-carboxylate | 745048-07-1 | MFCD04038543 | 257.37 | C13H27N3O2 | 100 MG

1-Boc-4-(4-aminobutyl)piperazine is a Boc-protected piperazine derivative used as a drug intermediate for the synthesis of active pharmaceutical compounds. It is offered in multiple laboratory-scale pack sizes for medicinal chemistry and organic synthesis applications.

Boc-protected piperazine scaffold suitable for medicinal chemistry.
Available in multiple lab-scale pack sizes, including 100 MG.
Molecular formula C13H27N3O2 and molecular weight 257.37.
Intended as a synthetic intermediate for the preparation of diverse active compounds.

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1,491

Ambeed AMBEED

5000895570 1-CBZ-AMINO-2-METHYLAMIN 250MG

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1,492

Apexbio Technology LLC Z-FA-FMK 105637-38-5;197855-65-5 10mg

Z-FA-FMK is a peptidyl fluoromethyl ketone inhibitor targeting cysteine proteases specifically cathepsins such as cathepsin B and certain caspases It does not require a P1 aspartate residue for inhibition Mechanistically Z-FA-FMK suppresses the enzyme activity of effector caspases (including caspases-2 -3 -6 and -7) but shows minimal impact on initiator caspases (caspase-8 and caspase-10) and only partial attenuation of caspase-9 activity As a negative control inhibitor Z-FA-FMK is regularly applied in apoptosis research to differentiate specific caspase-dependent signaling pathways and to assess the role of cathepsins and caspases in biological contexts such as cell death mechanisms and related pathways

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1,493

Medchemexpress LLC Z-LLY-FMK (Calpain Inhibitor IV) | 133410-84-1 | 98.7% | 557.65 | 100 MG

Z-LLY-FMK (Calpain Inhibitor IV) is a calpain inhibitor involved in apoptosis of many cell systems. It inhibits intestine apoptosis after common bile duct ligation and reduces parasite burden in mice challenged with *Taenia crassiceps* cysts. It can be used for the study of cysticercosis.

Calpain inhibitor
Inhibits apoptosis in various cell systems
Reduces parasite burden
Used for cysticercosis studies

Pricing & Availability

1,494

Medchemexpress LLC (Z)-Zolucatetide ((Z)-FOG-001; I-67) | 98.2% | 2076.39 | 5 MG

(Z)-Zolucatetide is a structural isomer of Zolucatetide and acts as a potent β-catenin inhibitor with an IC50 of <50 nM. It inhibits β-catenin and T-cell factor (TCF) transcription factor interaction, suppresses cell proliferation, and induces cell cycle arrest in target cells. It has shown anti-tumor efficacy in mice bearing COLO320DM colon cancer cell xenografts and can be used for the study of colon cancer.

Potent β-catenin inhibitor with an IC50 of less than 50 nM.
Inhibits β-catenin and T-cell factor (TCF) transcription factor interaction.
Suppresses cell proliferation.
Induces cell cycle arrest in target cells.
Exhibits anti-tumor efficacy in mice bearing COLO320DM colon cancer cell xenografts.
Useful for the study of colon cancer.

Pricing & Availability

1,495

eMolecules EMOLECULES INC

5000841244 1-CBZ-3-PYRROLIDINONE 25G

Pricing & Availability

1,496

Medchemexpress LLC Z-GLYCINOL 1KG

Z-GLYCINOL 1KG

Pricing & Availability

1,497

Medchemexpress LLC J147 | 1146963-51-0 | 99.5% | 350.34 | 100 MG

(E/Z)-J147 is an exceptionally potent, orally active neuroprotective agent that enhances cognitive function. It can easily cross the blood-brain barrier (BBB) and shows potential for the study of Alzheimer's disease (AD). It inhibits monoamine oxidase B (MAO B) and the dopamine transporter.

Neuroprotection and cognitive enhancement
Readily passes the blood-brain barrier (BBB)
Inhibits monoamine oxidase B (MAO B) with an EC50 value of 1.88 μM and the dopamine transporter with an EC50 value of 0.649 μM
Shows potential for the study of Alzheimer's disease (AD)
Promotes HT22 and primary cell survival in a dose-dependent manner, with an EC50 value range of 0.06-0.115 μM
Enhances memory and dendritic spine number in old mice when administered in their diet at 200 ppm for 6 months
Half-life (t1/2) in plasma is 1.5 hours and in the brain is 2.5 hours after a single oral dose of 20 mg/kg

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1,498

Medchemexpress LLC (E/Z)-SIS3 free base | 1009104-85-1 | MFCD24368989 | 99.5% | 453.53 | C28H27N3O3 | 100mg

E/Z-SIS3 free base exhibits an inhibitory efficacy against smad3 exhibits an anti-fibrotic and anti-inflammatory effect through a TGF- /smad3 signaling pathway[1]

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1,499

Cayman Chemical 5 Z 11 Z 14 ZEicosatrienoic A

5(Z),11(Z),14(Z)-Eicosatrienoic acid is a PUFA found in various natural sources including maritime pine (Pinus pinaster) seed oil (MPSO), gymnospermae leaves and seeds, and freshwater gastropods.{14273,14945,14947} A diet containing MPSO lowered HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to diminish cholesterol efflux in vitro.{14273} 5(Z),11(Z),14(Z)-Eicosatrienoic acid methyl ester, when topically applied, reduces inflammatory processes, potentially by displacing arachidonic acid from phospholipid pools and reducing downstream inflammatory products such as PGE2 and LTs.{14946}

Pricing & Availability

1,500

Aobchem (2-(Hydroxymethyl)-4 5-dimethoxyphenyl)boronic acid | 95% | CAS 2055472-45-0 | C9H13BO5 | 5g

(2-(Hydroxymethyl)-4 5-dimethoxyphenyl)boronic acid | 95% | CAS 2055472-45-0 | C9H13BO5 | 5g

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Pyrrolidines

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Medchemexpress LLC 1-Boc-3-aminopyrrolidine | 186550-13-0 | 99.9% | 186.25 | 10 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Boc-NH-PEG6-amine | 1091627-77-8 | 97.0% | C19H40N2O8 | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HS-PEG6-CH2CH2-Boc | 1818294-40-4 | >98.0% | C19H38O8S | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Boc-NH-PEG8-C2-Br | 2688072-12-8 | 99.8% | 576.52 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tert-butyl 4-(4-aminobutyl)piperazine-1-carboxylate | 745048-07-1 | MFCD04038543 | 257.37 | C13H27N3O2 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Z-LLY-FMK (Calpain Inhibitor IV) | 133410-84-1 | 98.7% | 557.65 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (Z)-Zolucatetide ((Z)-FOG-001; I-67) | 98.2% | 2076.39 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Z-GLYCINOL 1KG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC J147 | 1146963-51-0 | 99.5% | 350.34 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (E/Z)-SIS3 free base | 1009104-85-1 | MFCD24368989 | 99.5% | 453.53 | C28H27N3O3 | 100mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More