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Filtered Search Results
Medchemexpress LLC α-Amanitin | 23109-05-9 | MFCD00215842 | 99.9% | 918.97 g/mol | C39H54N10O14S | 500 UG
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α-Amanitin is a bicyclic peptide toxin that potently inhibits RNA polymerase II and is used as a research reagent and ADC payload component. The compound is supplied as a solid; it is unstable in solution and should be stored at -20°C protected from light, with solutions prepared fresh prior to use.
- Bicyclic peptide inhibitor of RNA polymerase II.
- High purity (99.9%).
- CAS number 23109-05-9.
- Molecular weight 918.97 g/mol.
- Soluble in water and DMSO with ultrasonic assistance; in vivo formulation protocols are reported.
- Store at -20°C, protect from light; unstable in solution-prepare fresh solutions.
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Medchemexpress LLC Bisindolylmaleimide I hydrochloride | 176504-36-2 | MFCD00236429 | 98.4% | 448.94 | C25H25ClN4O2 | 5 MG
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Bisindolylmaleimide I hydrochloride is a cell-permeable, reversible protein kinase C (PKC) inhibitor that also shows activity against GSK-3. It is supplied as a powder for research and analytical use, with reported potency in the low nanomolar range against PKC isoforms and a high reported purity.
- Cell-permeable, reversible PKC inhibitor
- Potent activity: IC50 ≈ 16-20 nM for PKC isoforms
- Also reported to inhibit GSK-3
- High purity (reported 98.4%)
- Supplied as a powder in small analytical pack sizes (for example, 1 mg, 5 mg, 10 mg)
- Recommended storage: powder at 4°C or -20°C; solutions at -20°C or -80°C
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Medchemexpress LLC 1-N-Boc-3-hydroxyaze | 25g
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1-N-Boc-3-hydroxyazetidine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) 1-N-Boc-3-hydroxyazetidine is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs
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Ambeed AMBEED
5000893244 BR-PEG4-CH2-BOC 250MG
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Ambeed AMBEED
5000894620 3-BOC-AMINOMETHYLPYRAZOLE 1GR
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Ambeed AMBEED
5000897234 S-N-BOC-2-2-HYDROXYETHYL 100MG
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Ambeed AMBEED
5000897167 1-BOC-3-ETHYNYLPYRROLIDI 250MG
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Ambeed AMBEED
5000896000 R-1-BOC-2-ISOPROPYLPIPER 250MG
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Ambeed AMBEED
5000893949 R-TERT-BUTYL PYRROLIDINE-3 1GR
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Ambeed AMBEED
5000894064 1-BOC-6-AMINOINDOLE 1GR
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Ambeed AMBEED
5000889815 1-BOC-OCTAHYDROPYRROLO34 250MG
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Apexbio Technology LLC (Z)-4-Hydroxytamoxifen 68047-06-3 5mg
(Z)-4-Hydroxytamoxifen is a biologically active metabolite of tamoxifen functioning as a selective estrogen receptor (ER) modulator As a nuclear receptor ER mediates cellular responses through ligand-induced conformational changes and transcriptional modulation Upon ligand binding ER alters gene expression patterns influencing cell proliferation differentiation and growth (Z)-4-Hydroxytamoxifen exhibits higher binding affinity to ER compared to its parent compound tamoxifen preferentially acting as an antagonist It has been widely employed in vitro and in vivo research models to investigate ER-mediated signaling pathways particularly related to hormone-dependent breast cancer proliferation and estrogen-driven physiological responses
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Apexbio Technology LLC N-3-oxo-dodecanoyl-L-Homoserine lactone(Synonyms: 3-Oxo-C12-HSL, N-(3-Oxododecanoyl)-L-homoserine lactone, OdDHL, 3-Oxododecanoyl homoserine lactone), 1mg, CAS: 168982-69-2.
N-3-oxo-dodecanoyl-L-Homoserine lactone (CAS 168982-69-2) commonly termed 3-O-C12-HSL is an acylhomoserine lactone (AHL) molecule utilized by Gram-negative bacteria such as Pseudomonas aeruginosa for quorum sensing This small lipid-soluble signaling molecule modulates virulence gene expression in response to bacterial population density In human pulmonary epithelial (16HBE) and lung fibroblast (L828) cell models exposure to 3-O-C12-HSL strongly elevates IL-8 transcription and secretion subsequently promoting neutrophil chemotaxis Thus 3-O-C12-HSL is extensively studied in pathogen-host interactions notably in respiratory infections associated with cystic fibrosis
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Sigma Aldrich Fine Chemicals Biosciences Cytochalasin B from Drechslera dematioidea | 14930-96-2 | MFCD00077704 | 5mg
Cytochalasin B from Drechslera dematioidea | Purity: ≥98% | Mol Wt: 479.61 | 14930-96-2 | MFCD00077704 | 5mg
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C=O | 250mg | 654491085](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000127040.jpg-250.jpg)
eMolecules 191348-04-6 | (S)-1-Boc-3-pyrrolidinecarbaldehyde | Synthonix | MFCD14635729 | 199.250 | C10H17NO3 | 95.000 | CC(C)(C)OC(=O)N1CC[C@@H](C1)C=O | 250mg | 654491085
(S)-1-Boc-3-pyrrolidinecarbaldehyde | Synthonix | 191348-04-6 | MFCD14635729 | 199.250 | C10H17NO3 | 95.000 | CC(C)(C)OC(=O)N1CC[C@@H](C1)C=O | 250mg | 654491085
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