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Filtered Search Results
Medchemexpress LLC Boc-NH-PEG8-C2-Br | 2688072-12-8 | 99.8% | 576.52 | 25 MG
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Boc-NH-PEG8-C2-Br is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is intended for research use only.
- Molecular weight: 576.52
- Chemical formula: C23H46BrNO10
- Appearance: Colorless to light yellow liquid
- Purity (HPLC): 99.8%
- Consistent with structure by 1H NMR and MS
- Applicable in cancer and cancer targeted therapy research
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Medchemexpress LLC Tert-butyl 4-(4-aminobutyl)piperazine-1-carboxylate | 745048-07-1 | MFCD04038543 | 257.37 | C13H27N3O2 | 100 MG
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1-Boc-4-(4-aminobutyl)piperazine is a Boc-protected piperazine derivative used as a drug intermediate for the synthesis of active pharmaceutical compounds. It is offered in multiple laboratory-scale pack sizes for medicinal chemistry and organic synthesis applications.
- Boc-protected piperazine scaffold suitable for medicinal chemistry.
- Available in multiple lab-scale pack sizes, including 100 MG.
- Molecular formula C13H27N3O2 and molecular weight 257.37.
- Intended as a synthetic intermediate for the preparation of diverse active compounds.
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Medchemexpress LLC Carbonic anhydrase, bovine erythrocytes | 9001-03-0 | 29.0 kDa | 10 MG
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Carbonic anhydrase, bovine erythrocytes (EC 4.2.1.1) is a ubiquitous zinc-containing metalloenzyme found in prokaryotes and eukaryotes. It catalyzes the reversible conversion of carbon dioxide to bicarbonate and protons. This enzyme can be utilized for research related to cancer, glaucoma, obesity, and epilepsy. For in vitro use, the lyophilized powder should be dissolved in ice-cold water at a concentration of 0.1 mg/mL and stored in an ice bath until use.
- Molecular weight: 29.0 kDa
- Optimal pH: 7.0-7.5
- Isoelectric point: 6.40
- Inhibitors include monovalent anions, sulfonates, sulfonamides, and imidazole
- Enzyme activity: ≥3000 U/mg solid
- Appearance: Solid
- Color: White to off-white
- Solubility: Soluble in water at ≥ 50 mg/mL
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Medchemexpress LLC Azido-PEG4-Boc | 581066-04-8 | 97% | C15H29N3O6 | 1 G
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Azido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It functions as a click chemistry reagent and can exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Contains an Azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
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Medchemexpress LLC Carbonic Anhydrase 4 100ug
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Carbonic anhydrase 4 catalyzes the reversible hydration of carbon dioxide and plays a crucial role in maintaining intracellular and extracellular pH Carbonic Anhydrase 4 Protein Human (HEK293 His) is the recombinant human-derived Carbonic Anhydrase 4 protein expressed by HEK293 with C-His labeled tag
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Medchemexpress LLC (Z)-Guggulsterone | 39025-23-5 | 99.4% | 312.45 | 10 MG
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(Z)-Guggulsterone is a constituent of the Indian Ayurvedic medicinal plant *Commiphora mukul*. It inhibits the growth of human prostate cancer cells by causing apoptosis and inhibits angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling axis. It also acts as a potent FXR antagonist and reduces ACE2 expression and SARS-CoV-2 infection.
- Inhibits growth of human prostate cancer cells by causing apoptosis
- Inhibits angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling axis
- Acts as a potent FXR antagonist
- Reduces ACE2 expression
- Reduces SARS-CoV-2 infection
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Medchemexpress LLC N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N-[(E)-(3-methoxyphenyl)methylideneamino]acetamide | 1146963-51-0 | MFCD25976644 | 99.8% | C18H17F3N2O2 | 10MG
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(E/Z)-J147 (N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N-[(E)-(3-methoxyphenyl)methylideneamino]acetamide) is a small-molecule research compound investigated for neuroprotective and cognitive-enhancing effects. It readily crosses the blood-brain barrier and has reported activity against monoamine oxidase B and the dopamine transporter. The material is supplied as a high-purity solid for laboratory use.
- High purity: 99.8% by supplier specification.
- Powder form, off-white to pink in color.
- Recommended solvent: DMSO soluble at ≥100 mg/mL.
- Storage: powder stable at -20°C (long term) and 4°C (short term).
- Demonstrated neuroprotective activity and blood-brain barrier penetration.
- For research use only; not for human or clinical use.
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Medchemexpress LLC E Z -MitoTam iodid 10mg | 10MG
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E Z -MitoTam iodid 10mg | 10MG
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Aobchem (Z)-2 3 6-trifluorobenzaldehyde oxime | 95% | CAS 1353013-21-4 | C7H4F3NO | 1g
(Z)-2 3 6-trifluorobenzaldehyde oxime | 95% | CAS 1353013-21-4 | C7H4F3NO | 1g
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eMolecules 271600-24-9 | (S)-3-N-CBZ-AMINO-PENTANOIC ACID | MFCD09991644 | 1g
Pharmablock | methyl tetralin-5-carboxylate | 25mg | 713712753 | PBTYJ796 | 66193-59-7 | MFCD15523539 | 190.242 | C12H14O2
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Medchemexpress LLC E Z -DEMETHOXYCURCU 5 mg
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E Z -DEMETHOXYCURCU 5MG
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eMolecules 194413-58-6 | (Z)-Semaxinib | Target Molecule | MFCD09763655 | 238.290 | C15H14N2O | 0.000 | Cc1cc(C)c(\C=C2/C(=O)Nc3ccccc23)[nH]1 | 25mg | 335411852
(Z)-Semaxinib | Target Molecule | 194413-58-6 | MFCD09763655 | 238.290 | C15H14N2O | 0.000 | Cc1cc(C)c(\C=C2/C(=O)Nc3ccccc23)[nH]1 | 25mg | 335411852
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Medchemexpress LLC (E/Z)-Locostatin | 133812-16-5 | 99.5% | 245.27 | 10 MG
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(E/Z)-Locostatin, also known as (E/Z)-UIC-1005, is a racemic form of Locostatin. This potent RKIP inhibitor works by binding to the Raf kinase inhibitor RKIP protein, thereby disrupting its interaction with Raf-1 kinase and G protein-coupled receptor kinase 2. It has been shown to inhibit cell proliferation and migration. It can also aggravate thioacetamide-induced acute liver failure in mice.
- Potent RKIP inhibitor
- Inhibits cell proliferation and migration
- Disrupts interaction of RKIP with Raf-1 kinase
- Disrupts interaction of RKIP with G protein-coupled receptor kinase 2
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Medchemexpress LLC Z-IETD-AFC | 219138-02-0 | 99.74% | 821.75 | 10 MG
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Z-IETD-AFC is a specific fluorescence substrate that can be used to determine caspase-8 catalytic activity.
- Specific fluorescence substrate
- Determines caspase-8 catalytic activity
- Appears as a white to off-white solid
- Has an emission wavelength of 500
- Has an excitation wavelength of 380
- Soluble in DMSO at concentrations greater than or equal to 100 mg/mL
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Medchemexpress LLC 7(Z),10(Z),13(Z)-hexadecatrienoic acid | 7561-64-0 | 98.2% | 250.38 | C16H26O2 | 1mg
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7(Z) 10(Z) 13(Z)-Hexadecatrienoic acid (Roughanic acid) is an -3 polyunsaturated fatty acid (PUFA) that can be found in the leaves of S olusatrum 7(Z) 10(Z) 13(Z)-Hexadecatrienoic acid is an intermediate in the biosynthesis of jasmonic acid [1][2]
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