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Filtered Search Results
Chem-Impex International, Inc. Allyloxycarbonyl N-hydroxyuccinimide ester | MFCD02684388 | 100G
Allyloxycarbonyl N-hydroxyuccinimide ester, MFCD02684388, 100G
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eMolecules 1185-53-1 | 2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride | Chem-Impex | MFCD00012590 | 157.590 | C4H12ClNO3 | 99.000 | Cl.NC(CO)(CO)CO | 1kg | 603113068
2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride | Chem-Impex | 1185-53-1 | MFCD00012590 | 157.590 | C4H12ClNO3 | 99.000 | Cl.NC(CO)(CO)CO | 1kg | 603113068
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Medchemexpress LLC Eltanexor Z-isomer | 1642300-78-4 | 96.0% | 428.29 g/mol | C17H10F6N6O | 100 MG
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Eltanexor Z-isomer is the geometric (Z) isomer of eltanexor, a small-molecule exportin-1 (XPO1/CRM1) inhibitor. Supplied for laboratory research use only, the compound is offered as a solid and as DMSO solutions across multiple pack sizes and is intended for in vitro studies and research applications.
- Less active geometric isomer of the parent compound.
- High purity suitable for research applications.
- Available as solid and as DMSO solution for convenience.
- Characterized by molecular formula and molecular weight for traceability.
- Intended for laboratory research use only; not for human or clinical use.
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Medchemexpress LLC (Z)-9-propenyladenine | 1464851-21-5 | MFCD30718180 | 175.19 g/mol | C8H9N5 | 100 MG
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(Z)-9-propenyladenine is the Z-isomer analytical standard of 9-propenyladenine used as a reference impurity for tenofovir disoproxil. It is supplied as a solid and as preprepared solutions in DMSO for analytical and method development use. Chemical formula C8H9N5; molecular weight 175.19 g/mol.
- Used as an analytical reference standard for impurity identification and quantitation.
- Supplied as solid and as 10 mM solutions in DMSO for convenience.
- Suitable for HPLC and LC-MS method development and validation.
- White to off-white solid appearance for visual inspection.
- Chemical formula and molecular weight provided for accurate calculations.
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eMolecules 940868-17-7 | 1-Cbz-Pipecolinamide | Oakwood Chemical | MFCD09878798 | 262.309 | C14H18N2O3 | 0.000 | NC(=O)C1CCCCN1C(=O)OCc1ccccc1 | 1g | 537694601
1-Cbz-Pipecolinamide | Oakwood Chemical | 940868-17-7 | MFCD09878798 | 262.309 | C14H18N2O3 | 0.000 | NC(=O)C1CCCCN1C(=O)OCc1ccccc1 | 1g | 537694601
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eMolecules 168399-08-4 | Methyl (S)-3-Cbz-2-oxoimidazolidine-4-carboxylate | Accela ChemBio (ASD) | MFCD28007693 | 278.264 | C13H14N2O5 | 95.000 | COC(=O)[C@@H]1CNC(=O)N1C(=O)OCc1ccccc1 | 1g | 560592283
Methyl (S)-3-Cbz-2-oxoimidazolidine-4-carboxylate | Accela ChemBio (ASD) | 168399-08-4 | MFCD28007693 | 278.264 | C13H14N2O5 | 95.000 | COC(=O)[C@@H]1CNC(=O)N1C(=O)OCc1ccccc1 | 1g | 560592283
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Medchemexpress LLC 1- Cbz-amino cyclope 5g
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1-(Cbz-amino)cyclopentanecarboxylic acid (Cbz-cycloleucine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research
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Medchemexpress LLC 1- Cbz-amino cyclope 10g
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1-(Cbz-amino)cyclopentanecarboxylic acid (Cbz-cycloleucine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research
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Medchemexpress LLC (Z,E)-9,12-tetradecadien-1-ol | 42521-46-0 | MFCD00270832 | >95.0% | 210.36 g/mol | C14H26O | 1mL
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(Z E)-9 12-Tetradecadienol is a synthetic enhancer of male Ephestia cautella attraction[1]
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Medchemexpress LLC Cbz-NH-PEG4-C2-acid | 756526-00-8 | MFCD11041139 | 95.0% | 399.44 g/mol | C19H29NO8 | 250 MG
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Cbz-NH-PEG4-C2-acid is a PEG-based linker designed for PROTAC synthesis. It features a Cbz-protected amino group and a terminal carboxylic acid separated by a four-unit ethylene glycol spacer, providing solubility and flexibility for conjugation. The compound is intended for use in medicinal chemistry to connect ligands and enable targeted protein degrader construction.
- Cbz-protected amino group for selective deprotection
- Terminal carboxylic acid enables standard amide-coupling chemistries
- PEG4 spacer imparts flexibility and improves solubility
- Suitable for PROTAC linker construction and linker optimization studies
- Available in common laboratory pack sizes for synthesis workflows
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Medchemexpress LLC (Z)-10-Hydroxynortriptyline | 47132-19-4 | 99.7% | 279.38 | 1 MG
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(Z)-10-Hydroxynortriptyline is a metabolite of Nortriptyline, a tricyclic antidepressant and the main active metabolite of Amitriptyline. It is used to relieve symptoms of depression and is intended for research use only.
- Metabolite of Nortriptyline
- Can be used to relieve symptoms of depression
- Available as a white to off-white solid
- Powder storage at -20°C for 3 years or 4°C for 2 years
- In solvent storage at -80°C for 6 months or -20°C for 1 month
- Ships at room temperature within the continental US
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Medchemexpress LLC E/Z-necrosulfonamide | 432531-71-0 | 98.8% | 461.47 g·mol⁻¹ | C18H15N5O6S2 | 100 MG
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(E/Z)-Necrosulfonamide is a racemic small-molecule inhibitor of mixed lineage kinase domain-like protein (MLKL) and gasdermin D (GSDMD), used in cellular research to probe necroptosis and pyroptosis pathways. Supplied as a solid powder with high reported purity, the compound is provided in multiple package sizes and requires cold storage for long-term stability.
- Inhibits MLKL- and GSDMD-mediated cell death.
- High reported purity suitable for research assays.
- Available in multiple package sizes for experimental flexibility.
- Solid powder form simplifies handling and storage.
- Stable under recommended refrigerated or frozen storage.
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Medchemexpress LLC Z-FF-FMK | 105608-85-3 | 96.0% | C27H27FN2O4 | 25 MG
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Z-FF-FMK is a selective cathepsin-L inhibitor. It can prevent β-amyloid from inducing apoptotic changes such as activation of caspase-3, cleavage of the DNA repair enzyme, poly-ADP ribose polymerase, and DNA fragmentation.
- Selective cathepsin-L inhibitor
- Prevents β-amyloid induced apoptotic changes
- Inhibits caspase-3 activation
- Cleavage of DNA repair enzyme, poly-ADP ribose polymerase, and DNA fragmentation
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Medchemexpress LLC Benzenepropanoic acid, α-[2-[4-(3,4-dichlorophenyl)-2-thiazolyl]hydrazinylidene]-2-nitro-, (αZ)- | 901787-88-0 | 98.0% | 451.28 | 25 MG
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(Z)-4EGI-1 is the Z-isomer of 4EGI-1, functioning as an inhibitor of eIF4E/eIF4G interaction and translation initiation. It binds effectively to eIF4E with an IC50 of 43.5 μM and a Kd value of 8.74 μM, and exhibits anticancer activity. In vitro studies with melanoma cells showed that treatment with (Z)-4EGI-1 significantly reduced the expression of regulatory proteins such as cyclin D1, cyclin E, and Survivin, while housekeeping proteins remained unaffected. It also inhibits the proliferation of cancer cells.
- Functions as an inhibitor of eIF4E/eIF4G interaction and translation initiation.
- Binds to eIF4E with an IC50 of 43.5 μM and a Kd value of 8.74 μM.
- Exhibits anticancer activity.
- Reduces expression of regulatory proteins like cyclin D1, cyclin E, and Survivin.
- Inhibits the proliferation of cancer cells with IC50 values of 15.3 μM for breast cells and 11.6 μM for melanoma cells.
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Medchemexpress LLC Nikkomycin Z | 59456-70-1 | 98.6% | 495.44 | 1 MG
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Nikkomycin Z is an orally active nucleoside peptide antifungal agent. It functions by inhibiting chitin synthesis, acting as a competitive analogue of the chitin synthase substrate UDP-N-acetylglucosamine. This compound demonstrates antifungal activity and enhances efficacy when combined with echinocandins such as Caspofungin and Micafungin. In vivo studies show it reduces fungal burden and extends survival in murine models of *Histoplasma capsulatum* infection.
- Inhibits chitin synthesis
- Competitive analogue of UDP-N-acetylglucosamine
- Active against *Candida albicans* and *Candida parapsilosis*
- Enhances efficacy with echinocandins
- Reduces fungal burden in *Histoplasma capsulatum* infection models
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