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Filtered Search Results
Medchemexpress LLC Protac Bcl2 degrader-1 | 2378801-85-3 | 99.8% | 941.84 g/mol | C45H45BrN6O10S | 10MG
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PROTAC Bcl2 degrader-1 is a cereblon-based proteolysis targeting chimera designed to selectively induce degradation of Bcl-2 and to show activity against Mcl-1. It is intended for biochemical and cellular research, supplied as a light yellow to yellow solid with high chemical purity and characterized potency in degradation assays.
- Induces degradation of Bcl-2 and shows activity against Mcl-1.
- Reported Bcl-2 IC50 4.94 μM and DC50 3.0 μM.
- High chemical purity of 99.8%.
- Molecular weight approximately 941.8 g/mol.
- Supplied as a light yellow to yellow solid for research use.
- Recommended storage at -20°C under inert gas; solvent stability and handling details available in technical documents.
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Medchemexpress LLC (2S,3S)-2-acetamido-3-methylpentanoic acid | 3077-46-1 | MFCD00066072 | 98.8% | 173.21 g/mol | C8H15NO3 | 100 G
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(2S,3S)-2-Acetamido-3-methylpentanoic acid is an N-acetylated isoleucine derivative supplied as a high-purity amino acid reagent for biochemical and analytical research. It is provided as a white to off-white solid and is suitable for workflows requiring an acetylated isoleucine analog.
- Purity 98.8%.
- Molecular formula C8H15NO3 and molecular weight 173.21 g/mol.
- Appearance white to off-white solid.
- Solubility in DMSO 14 mg/mL; ultrasonic and warming recommended.
- Powder storage: -20°C (3 years) or 4°C (2 years); in solvent short-term storage at -80°C or -20°C.
- For research use only; not for human or clinical use.
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eMolecules 2R 3R-BUTANE-2 3-DIOL 1G
5000170628 2R 3R-BUTANE-2 3-DIOL 1G
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Medchemexpress LLC 1H-1,2,4-triazole-1-ethanol, β-[(4-chlorophenyl)methyl]-α-methyl-α-phenyl-, (αR,βS)- | 259200-30-1 | 99.8% | 5MG
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1H-1,2,4-triazole-1-ethanol, β-[(4-chlorophenyl)methyl]-α-methyl-α-phenyl-, (αR,βS)- | 259200-30-1 | 99.8% | 5MG
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Apexbio Technology LLC 2'-Azido-dATP 50ul (100 mM)
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2p-Azido-dATP is a sugar-modified nucleoside triphosphate analog It incorporates a 2 -azido group substitution at the sugar moiety which allows its enzymatic integration into nucleic acids and leads to oligonucleotide derivatives with modified biochemical and biophysical characteristics 2p-Azido-dATP exerts its biological activity primarily through structural incorporation into nucleic acids during polymerization resulting in increased nuclease stability enhanced target binding affinity and reduced immunogenicity Based on these properties 2p-Azido-dATP holds research potential in nucleic acid therapeutics such as antisense oligonucleotides siRNA development gene-editing and aptamer-based applications
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Selleck Chemical LLC ACT-1016-0707-E1941-25MG
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ACT-1016-0707 (LPA1 receptor antagonist 2) is an orally active and selective antagonist of LPA1 Receptor with IC50 of 3 1 nM for hLPAR1 in tango assay It has the potential to treat fibrotic diseases
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Medchemexpress LLC (2S)-Octyl-α-hydroxyglutarate | 1391194-64-1 | 95.0% | 260.33 g/mol | C13H24O5 | 1 ML
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(2S)-Octyl-α-hydroxyglutarate is a cell-permeable octyl-ester derivative of the S-isomer of 2-hydroxyglutarate supplied for research use. It is commonly provided as a 10 mM solution in DMSO (1 mL vial) and is used as a cell-permeant precursor to L-2-hydroxyglutarate in cellular and epigenetic studies.
- Cell-permeable octyl ester of S-2-hydroxyglutarate.
- Provided as a 10 mM solution in DMSO, 1 mL vial.
- Molecular formula C13H24O5; molecular weight 260.33 g/mol.
- Intended for in vitro research use only; not for human or clinical use.
- Used in studies of cellular metabolism and histone methylation.
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eMolecules BOC-ISOGUVACINE 5G
5000188263 BOC-ISOGUVACINE 5G
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eMolecules EMOLECULES INC
5000470811 3R-3-TERT-BUTOXYCARBON 100G
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eMolecules EMOLECULES INC
5000470806 3R-3-TERT-BUTOXYCARBON 2.5G
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eMolecules EMOLECULES INC
5000470475 4-1-TERT-BUTOXYCARBONYLP 1G
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Medchemexpress LLC TMEM219/IGFBP-3R Hu 20ug | 20ug
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The TMEM219/IGFBP-3R protein was identified as an IGFBP3-specific cell death receptor and a potential mediator of caspase-8-dependent apoptosis upon ligand binding This protein actively binds to IGFBP3 forming a key molecular interaction that may initiate the apoptosis signaling pathway TMEM219/IGFBP-3R Protein Human (HEK293 Fc) is the recombinant human-derived TMEM219/IGFBP-3R protein expressed by HEK293 with C-hFc labeled tag
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eMolecules N-BOC-DOLAPROINE 100MG
5000190744 N-BOC-DOLAPROINE 100MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000669686 Z-INDIRUBIN STAND 25MG
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Medchemexpress LLC (R)-pyrrolidine-2-carboxylic acid ((+)-(R)-proline | 344-25-2 | 98.0% | 115.13 | 25 G
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(R)-pyrrolidine-2-carboxylic acid ((+)-(R)-proline | 344-25-2 | 98.0% | 115.13 | 25 G
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