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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000380921 RAC -JBJ-04-125-02 25MG
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Medchemexpress LLC (Rac)-etavopivat | 2622070-93-1 | MFCD34578328 | 99.9% | 457.50 | C22H23N3O6S | 5 MG
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(Rac)-Etavopivat is the racemic isomer of etavopivat, an orally active erythrocyte pyruvate kinase-R (PKR) activator used in preclinical research on sickle cell disease and other hemoglobinopathies. Supplied as a high-purity research chemical, it is intended for biochemical and cellular studies investigating PKR activation and related mechanisms.
- Racemic isomer suitable for comparative pharmacology studies.
- Orally active PKR activator mechanism relevant to sickle cell research.
- High purity 99.9% for reproducible experimental results.
- Molecular formula C22H23N3O6S and molecular weight 457.50 for accurate calculations.
- Available in small-vial quantities for laboratory use.
- Stable when stored as recommended, supporting long-term storage.
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eMolecules 3S-3-FORMYL-1-PYRROLIDIN 10G
5000159174 3S-3-FORMYL-1-PYRROLIDIN 10G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000657007 N-ETHYLMALEIMIDE 10MM/1ML
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Medchemexpress LLC Z-LLY-FMK | 133410-84-1 | 98.7% | 557.65 g/mol | C30H40FN3O6 | 5 MG
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Z-LLY-FMK (Calpain Inhibitor IV) is a cell-permeable, irreversible peptide-based inhibitor of calpain proteases used in research to investigate apoptosis and parasite infection models. It is supplied as a solid powder with high reported purity and characterized chemical properties for laboratory use.
- Irreversible inhibitor of calpain proteases, useful for apoptosis studies.
- Cell-permeable peptide suitable for in vitro and in vivo research.
- High purity (~98.7%) for reliable experimental results.
- White to off-white solid with good solubility in common organic solvents.
- Stability information provided for powder and solution storage.
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Medchemexpress LLC 2'-Azido-2'-deoxycytidine | 51034-68-5 | C9H12N6O4 | 25 MG
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2'-Azido-2'-deoxycytidine is a purine nucleoside analogue with broad antitumor activity, targeting indolent lymphoid malignancies. Its anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis.
- Functions as a click chemistry reagent due to its Azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
- Requires double phosphorylation to become an inhibitor of nucleotide reductase
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000383839 AZIDO-PEG11-AZIDE 50MG
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eMolecules N-BOC-DOLAPROINE 1G
5000158895 N-BOC-DOLAPROINE 1G
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Medchemexpress LLC Z-VDVAD-FMK | 210344-92-6 | ≥98.0% | 695.73 | 25 MG
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Z-VDVAD-FMK is a special inhibitor of caspase-2, observed to reduce Lovastatin-induced apoptosis. It significantly diminishes Lovastatin-induced DNA loss and inhibits Rho-kinase activity in HMEC-1 cells when stimulated by Thrombin.
- Inhibits caspase-2
- Reduces Lovastatin-induced apoptosis
- Prevents many morphological features of apoptosis in cotreatment with other caspase inhibitors
- Greatly inhibits Rho-kinase activity in HMEC-1 cells stimulated by Thrombin
- Significantly reduces Lovastatin-induced loss of DNA
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000704377 RAC-CHEM-0199 50MG
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eMolecules N-BOC-2- 2- 2-2-BROMOETHOX 1G
5000224652 N-BOC-2- 2- 2-2-BROMOETHOX 1G
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Medchemexpress LLC Cyclopentanecarboxylic acid, 3-[[(1,1-dimethylethoxy)carbonyl)amino]-, (1S,3R)- | 261165-05-3 | 229.27 | 5 G
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BOC-(1S,3R)-3-aminocyclopentanecarboxylic acid is a synthetic intermediate primarily used in pharmaceutical synthesis. This product is intended for research purposes only and not for patient use.
- Useful for pharmaceutical synthesis
- Appears as a white to off-white solid
- Purity of 98.0%
- Stable at room temperature for 3 years
- Stable in solvent at -80°C for 2 years and -20°C for 1 year
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Medchemexpress LLC HY-42424A 100mg Medchemexpress, (S,R,S)-AHPC-Me (dihydrochloride) CAS: Purity:>98%
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Medchemexpress, HY-42424A 100mg (S,R,S)-AHPC-Me (dihydrochloride) CAS: (S,R,S)-AHPC-Me dihydrochloride (VHL ligand 2 dihydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein [1] . (S,R,S)-AHPC-Me dihydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC 50 <1 nM [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-18767 10mg Medchemexpress, Ivosidenib CAS:1448347-49-6 Purity:>98%
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Medchemexpress, HY-18767 10mg Ivosidenib CAS:1448347-49-6 Ivosidenib (AG-120) is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme, it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib (AG-120) has the potential for AML therapy due to its acceptable safety profile and clinical activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000704186 N-METHYLISATOIC ANHY 5G
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