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Filtered Search Results
Medchemexpress LLC N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-4'-((4-(7-((2-(2,6-dioxopiperidin-3-yl)-1, 3-d | 2641601-67-2 | MFCD16652626 | 99.4% | 942.15 | C54H67N7O8 | 10 MG
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PROTAC EZH2 Degrader-1 is a research-grade proteolysis-targeting chimera that induces degradation of EZH2 and inhibits its methyltransferase activity. It is intended for in vitro target validation and biochemical studies and is supplied with analytical documentation for research use.
- Potent EZH2 degradation with IC50 = 2.7 nM.
- High purity (99.44%) suitable for biochemical assays.
- Molecular weight 942.15 and formula C54H67N7O8.
- Supplied in small-mass pack sizes appropriate for laboratory research.
- Includes accompanying analytical documents: datasheet, COA, HNMR, and LCMS.
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Medchemexpress LLC (S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride | 2376990-26-8 | 96.3% | 632.64 | 50 MG
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(S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates (S,R,S)-AHPC based VHL ligand
- Utilizes a linker used in PROTAC technology
- Suitable for cancer and cancer targeted therapy research
- Functions as an E3 ligase ligand-linker conjugate inhibitor
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Medchemexpress LLC β-amanitin | 21150-22-1 | MFCD00151212 | >98.0% | 918.96 g/mol | C39H54N10O14S | 1 MG
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β-Amanitin is a cyclic peptide toxin isolated from Amanita phalloides that potently inhibits eukaryotic RNA polymerase II and, to a lesser extent, RNA polymerase III, blocking mRNA synthesis and protein production. It is used as a biochemical research reagent to study transcription, RNA polymerase function, and as a cytotoxic payload in antibody-drug conjugate research.
- Potent inhibitor of RNA polymerase II and III.
- High purity (>98%) suitable for biochemical studies.
- Soluble in DMSO at high concentration for stock preparation.
- Appropriate for use as an ADC cytotoxic payload or molecular biology tool.
- Supplied in small research quantities for laboratory applications.
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eMolecules 2417296-84-3 | Medchem Express | PROTAC BRAF-V600E degrader-1 | 1mg | 769193400 | HY-137487 | 1001.08 | C48H54F2N10O10S
Medchem Express | NSC-207895 | 5mg | 705861177 | HY-14714 | 58131-57-0 | MFCD01660065 | 279.256 | C11H13N5O4
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eMolecules 262438-43-7 | ATN-161 | MFCD30478885 | 50mg
Ambeed | 2-Chloro-3-hydrazinylpyrazine | 250mg | 552743627 | A562796 | 63286-28-2 | MFCD08272804 | 144.560 | C4H5ClN4
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Medchemexpress LLC 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | 99.1% | 434.49 g/mol | C24H26N4O4 | 25 MG
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CUDC-101 is a small-molecule inhibitor that concurrently targets histone deacetylases (HDACs) and receptor tyrosine kinases EGFR and HER2, used in biochemical and cell-based research. It is supplied as a solid and as DMSO solutions and is intended for research use only (not for human or clinical use).
- Dual inhibition of HDAC and EGFR/HER2 for pathway-specific studies.
- Potent activity with reported IC50s: HDAC 4.4 nM, EGFR 2.4 nM, HER2 15.7 nM.
- High purity (~99%) suitable for sensitive assays.
- Available in small milligram quantities and DMSO solutions for assay preparation.
- Formulated for laboratory research; follow safety data sheet guidance for handling.
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Medchemexpress LLC HY-50846 10mg Medchemexpress, SCH772984 CAS:942183-80-4 Purity:>98%
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Medchemexpress, HY-50846 10mg SCH772984 CAS:942183-80-4 SCH772984 is a highly selective and ATP-competitive ERK inhibitor, with IC50s of 4 and 1 nM for ERK1 and ERK2, respectively. SCH772984 has antitumor activity in MAPK inhibitor-naïve and MAPK inhibitor-resistant cells containing BRAF or RAS mutations. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Factor B-IN-1 | 1481631-75-7 | 95.0% | 332.36 g·mol⁻¹ | C19H16N4O2 | 5 MG
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Factor B-IN-1 is a research-grade small-molecule inhibitor of complement Factor B intended for in vitro and in vivo studies. The compound has formula C19H16N4O2, molecular weight 332.36 g·mol⁻1, CAS 1481631-75-7, and is supplied at high purity for laboratory use. Refer to the product datasheet for handling, solubility, and storage instructions.
- Small-molecule inhibitor of complement Factor B.
- Molecular formula C19H16N4O2; molecular weight 332.36 g·mol⁻1.
- Purity typically 95.0%.
- Soluble in DMSO (≈50 mg/mL) and formulatable for in vivo use.
- Powder storage at -20°C; store solutions at -80°C for long term.
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Medchemexpress LLC HY-18767 10mg Medchemexpress, Ivosidenib CAS:1448347-49-6 Purity:>98%
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Medchemexpress, HY-18767 10mg Ivosidenib CAS:1448347-49-6 Ivosidenib (AG-120) is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme, it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib (AG-120) has the potential for AML therapy due to its acceptable safety profile and clinical activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC 1,2,4-trideoxy-4-(methylamino)-1-(4-pentylphenyl)-D-erythro-pent-1-enitol hydrochloride | 1072443-89-0 | >98.0% | 313.86 g/mol | C17H27NO2·HCl | 25 MG
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SK1-I is a research compound that selectively inhibits sphingosine kinase 1 (SPHK1). It is supplied as the hydrochloride salt (CAS 1072443-89-0) in a 25 mg quantity for laboratory research use only; not for human or veterinary use.
- Selective SPHK1 inhibitor with reported Ki ~10 μM.
- Provided as a hydrochloride salt for improved stability.
- Purity ≥98% (HPLC), suitable for biochemical studies.
- Common applications include cell signaling and anticancer research.
- Store at recommended low temperature to maintain integrity.
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eMolecules 916141-36-1 | Medchem Express | TCS 1102 | 10mg | 446259443 | HY-10900 | MFCD18086894 | 470.59 | C27H26N4O2S
Medchem Express | TCS 1102 | 10mg | 446259443 | HY-10900 | 916141-36-1 | MFCD18086894 | 470.590 | C27H26N4O2S
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Medchemexpress LLC HY-B0596 100mg Medchemexpress, Taltirelin TA-0910 CAS:103300-74-9 Purity:98%
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Medchemexpress,HY-B0596 100mg Taltirelin TA-0910 CAS:103300-74-9 Formula:C17H23N7O5 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 1448188-69-9 | Medchem Express | VL285 Phenol | 5mg | 788478474 | HY-151227 | 548.66 | C29H32N4O5S
Ambeed | (R)-2-Phenylglycine methyl ester hydrochloride | 100g | 552631413 | A189810 | 19883-41-1 | MFCD00137487 | 201.650 | C9H12ClNO2
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Medchemexpress LLC (S,R,S)-AHPC | 1448297-52-6 | MFCD29049827 | 99.1% | 430.56 g/mol | C22H30N4O3S | 100MG
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(S,R,S)-AHPC is a VH032-derived VHL ligand used to recruit the von Hippel-Lindau E3 ligase in PROTAC and targeted protein degradation research. Supplied as a powder for research use, it has CAS 1448297-52-6, chemical formula C22H30N4O3S, molecular weight 430.56 g/mol, and measured HPLC purity 99.13%.
- Provides high-purity VHL ligand suitable for PROTAC construction.
- Powder form for easy storage and handling.
- Stable under recommended storage conditions (powder: -20°C/4°C; in solvent: -80°C/-20°C).
- Soluble in DMSO and water with ultrasonic assistance for formulation.
- Available in small research pack sizes for early-stage studies.
- Characterized by HPLC and LCMS to confirm identity and purity.
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![Strem, An Ascensus Company CAS 1357562-63-0. 50mg. 1-(2S)-1-[(11bS)-26-Dimethyldinaphtho[21-d12-f][132]dioxaphosphepin-4-yloxy]propan-2-yl-3-phenylurea min. 97%. MFCD18827630](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00009818-15-2204.JPG-250.jpg)
Strem, An Ascensus Company CAS 1357562-63-0. 50mg. 1-(2S)-1-[(11bS)-26-Dimethyldinaphtho[21-d12-f][132]dioxaphosphepin-4-yloxy]propan-2-yl-3-phenylurea min. 97%. MFCD18827630
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CAS 1357562-63-0. 50mg. 1-(2S)-1-[(11bS)-26-Dimethyldinaphtho[21-d12-f][132]dioxaphosphepin-4-yloxy]propan-2-yl-3-phenylurea min. 97%. MFCD18827630. Molecular Weight 536.56. Molecular Formula C32H29N2O4P. Color/form white pwdr. Strem 15-2204. http//www.strem.com/catalog/v/15-2204/
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