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Filtered Search Results
Medchemexpress LLC Taltirelin acetate (TA-0910 acetate) | 1549593-23-8 | 99.4% | 50 MG
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Taltirelin acetate (TA-0910 acetate) is an acetate form of Taltirelin (TA-0910), an orally effective analogue of thyrotropin releasing hormone (TRH) and a TRH receptor (TRH-R) superagonist. This compound can cross the blood-brain barrier and stimulates an increase in cytosolic Ca2+ concentration.
- Orally effective analogue of thyrotropin releasing hormone (TRH)
- TRH receptor (TRH-R) superagonist
- Can cross the blood-brain barrier
- Stimulates an increase in cytosolic Ca2+ concentration (Ca2+ release)
- Increases cell viability and reduces apoptosis in SH-SY5Y cells and primary rat mesencephalic neurons
- Demonstrates neuroprotective effects in cellular and animal models of Parkinson's disease
- Alleviates fatigue-like behavior in mouse models of cancer-related fatigue
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eMolecules 1166227-08-2 | Medchem Express | A66 | 5mg | 446262599 | HY-13261 | MFCD22378485 | 393.52 | C17H23N5O2S2
Medchem Express | HQ461 | 5mg | 713706705 | HY-144981 | 1226443-41-9 | 345.440 | C15H15N5OS2
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![Medchemexpress LLC (2S)-N-(3,5-dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide | 1361321-96-1 | MFCD28502270 | 99.5% | 388.48 g/mol | C20H24N2O4S | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000248904.png-250.jpg)
Medchemexpress LLC (2S)-N-(3,5-dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide | 1361321-96-1 | MFCD28502270 | 99.5% | 388.48 g/mol | C20H24N2O4S | 50 MG
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ACT-462206 is an orally active, brain-penetrant dual orexin 1/orexin 2 receptor antagonist supplied as a high-purity research reagent. It exhibits nanomolar potency (IC50 ≈ 60 nM for OX1 and 11 nM for OX2) and is used in preclinical studies of sleep regulation, anxiety-related disorders, and addiction.
- Dual orexin 1/2 receptor antagonist with nanomolar potency.
- Brain-penetrant compound suitable for central nervous system studies.
- High purity (≈99.5%) for reliable experimental results.
- Available in small-quantity packs for research use.
- Stable under recommended storage conditions to preserve integrity.
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Medchemexpress LLC Glecaprevir | 1365970-03-1 | 838.87 | 100 MG
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Glecaprevir is a novel HCV NS3/4A protease inhibitor and a SARS-CoV 3CLpro inhibitor. It is intended for use as a laboratory chemical and for the manufacture of substances, exclusively for research purposes and by experienced personnel.
- HCV NS3/4A protease inhibitor
- SARS-CoV 3CLpro inhibitor
- IC50 values ranging from 3.5 to 11.3 nM (HCV NS3/4A protease)
- IC50 of 4.09 μM (SARS-CoV 3CLpro)
- For research use only
- Intended for experienced personnel
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eMolecules 1350514-68-9 | Medchem Express | Grazoprevir | 5mg | 446265386 | HY-15298 | MFCD25976700 | 766.91 | C38H50N6O9S
Ambeed | (3-Fluoro-2-methylphenyl)boronic acid | 1g | 552671180 | A242930 | 163517-61-1 | MFCD07368679 | 153.950 | C7H8BFO2
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Innovative Research Inc Hmn PAI1 Rcmb WT Act 50ug
Human PAI-1 Recombinant Wild Type Active 50ug - Human PAI-1 Recombinant Wild Type Active from Innovative Research has been recombinantly produced in E. coli and purified by affinity chromatography. This is a Frozen liquid buffered in 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6 and a purity of >95% as determined by SDS-PAGE. More Details Species Human Target PAI-1 Purification Method Affinity purified Purity >95% as determined by SDS-PAGE Analysis Source E. coli Storage Conditions -70C Additional Information Gentle purification conditions create an active fraction that is greater than 99% pure and 98% active. This product can be used as a control in applications like ELISA and Western Blot. It can be used in a wide range of in vitro applications, including blocking/inhibition, fibrinolysis, plasminogen activation, receptor binding, in hypertension studies, for protein-protein interactions, and more.
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Medchemexpress LLC Protac BRD4 degrader-5-co-peg3-n3 | 2704602-92-4 | 99.7% | 1231.87 | C58H75ClN12O12S2 | 10 MG
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PROTAC BRD4 Degrader-5-CO-PEG3-N3 is a PROTAC-linker conjugate that combines a BRD4 degrader with a PEG-based linker and an azide functional group for bioconjugation. It is provided as a high-purity research reagent for targeted protein degradation studies and click-chemistry applications.
- azide functional group enables CuAAC and SPAAC conjugation
- high purity suitable for research use
- molecular weight 1231.87 and formula C58H75ClN12O12S2
- available in small milligram quantities, including 10 mg
- designed for use in antibody conjugation and linker chemistry workflows
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Medchemexpress LLC Protac EED degrader-1 | 2639882-72-5 | 98.3% | C55H60FN11O8S | 10MG
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PROTAC EED degrader-1 is a von Hippel-Lindau (VHL)-based proteolysis targeting chimera designed to bind and induce degradation of EED, a subunit of the polycomb repressive complex 2 (PRC2). It exhibits potent biochemical and cellular activity, leads to downregulation of EZH2 and H3K27me3, and has shown cellular apoptosis and antitumor effects in preclinical models.
- Potent EED-targeting degrader with low nanomolar biochemical activity.
- Reduces EZH2 protein levels and decreases H3K27me3 in cells.
- Induces apoptosis and shows antitumor activity in preclinical models.
- High reported purity for research applications.
- Available in multiple small-scale quantities for laboratory studies.
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eMolecules 2639528-48-4 | Medchem Express | (SRS)-AHPC-Me-C7 ester | 50mg | 686240373 | HY-130640 | 614.8 | C32H46N4O6S
Ambeed | 4-Ethynylbenzaldehyde | 1g | 552665775 | A234214 | 63697-96-1 | MFCD05664348 | 130.146 | C9H6O
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Medchemexpress LLC HY-10900 10mg Medchemexpress, TCS 1102 CAS:916141-36-1 Purity:>98%
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Medchemexpress, HY-10900 10mg TCS 1102 CAS:916141-36-1 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Protac Mcl1 degrader-1 | 2163793-38-0 | 98.1% | 909.84 g/mol | C45H45BrN6O8S | 5MG
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PROTAC Mcl1 degrader-1 is a cereblon-based proteolysis targeting chimera (PROTAC) that induces ubiquitination and proteasomal degradation of the anti-apoptotic protein Mcl-1. It is provided as a small-molecule research compound for in vitro and in vivo studies; reported properties include molecular formula C45H45BrN6O8S, molecular weight 909.84 g/mol, CAS 2163793-38-0, and a reported IC50 of 0.78 μM for Mcl-1 activity. Recommended solvents and in vivo formulations are provided in the manufacturer datasheet.
- Induces cereblon-mediated degradation of Mcl-1.
- Potent Mcl-1 activity with reported IC50 of 0.78 μM.
- Molecular weight 909.84 g/mol and formula C45H45BrN6O8S.
- High solubility in DMSO; documented in vitro and in vivo formulations.
- Intended for biochemical and cell-based research applications.
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Medchemexpress LLC Pasireotide acetate | 396091-76-2 | 99.5% | 1107.26 | 50 MG
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Pasireotide acetate is a long-acting cyclohexapeptide somatostatin analogue that improves agonist activity at somatostatin receptors. It can suppress GH, IGF-I, and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. This compound also exhibits antisecretory, antiproliferative, and proapoptotic activity.
- Improves agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively).
- Suppresses GH, IGF-I, and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease.
- Exhibits antisecretory, antiproliferative, and proapoptotic activity.
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eMolecules 1426916-02-0 | Medchem Express | ML-298 | 5mg | 791206317 | HY-116165 | MFCD28411618 | 432.447 | C22H23F3N4O2
Ambeed | (246-Triethylbenzene-135-triyl)trimethanamine trihydrochloride | 100mg | 633659373 | A1158523 | 190779-64-7 | MFCD15144745 | 358.780 | C15H30Cl3N3
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Medchemexpress LLC Protac Mcl1 degrader-1 | 2163793-38-0 | 98.1% | 909.84 g·mol⁻¹ | C45H45BrN6O8S | 10MG
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PROTAC Mcl1 degrader-1 is a cereblon-recruiting proteolysis-targeting chimera (PROTAC) designed to induce ubiquitination and proteasomal degradation of the anti-apoptotic protein Mcl-1. Supplied for research use, it is intended for biochemical and cellular studies of targeted protein degradation and Mcl-1 biology.
- Induces ubiquitination and proteasomal degradation of Mcl-1.
- Uses a cereblon E3 ligase ligand to recruit degradation machinery.
- High purity suitable for biochemical and cellular assays.
- Soluble in DMSO for compound handling and dosing.
- Available in multiple small-scale pack sizes for research use.
- Not for human or clinical use.
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Echelon Biosciences Research Labs Endothelin Receptor Antagonist BQ 3020; Acetyl-[Ala11,15]-ET 1 (6-21) - 0.5 mg, CAS#: 143113-45-5
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Endothelin Receptor Antagonist BQ 3020; Acetyl-[Ala11,15]-ET 1 (6-21) - 0.5mg , Ac-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH This item is non returnable
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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