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Filtered Search Results
Cayman Chemical NArachidonyl Maleimide
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A potent inhibitor of monoacylglycerol lipase (IC50 = 140 nM in rat cerebellar membranes)
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Cayman Chemical 5 Z 11 Z 14 ZEicosatrienoic A
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5(Z),11(Z),14(Z)-Eicosatrienoic acid is a PUFA found in various natural sources including maritime pine (Pinus pinaster) seed oil (MPSO), gymnospermae leaves and seeds, and freshwater gastropods.{14273,14945,14947} A diet containing MPSO lowered HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to diminish cholesterol efflux in vitro.{14273} 5(Z),11(Z),14(Z)-Eicosatrienoic acid methyl ester, when topically applied, reduces inflammatory processes, potentially by displacing arachidonic acid from phospholipid pools and reducing downstream inflammatory products such as PGE2 and LTs.{14946}
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Cayman Chemical Tetratriaconta16 Z 19 Z 22 Z
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A C34:6 VLCPUFA whose specific biological actions are largely unknown
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Cayman Chemical 9 Z 11 E 13 EOctadecatrienoic
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α-ESA methyl ester is a neutral, more lipid soluble form of the free acid.
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Cayman Chemical 5 Z 11 Z 14 ZEicosatrienoic A
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5(Z),11(Z),14(Z)-Eicosatrienoic acid is a PUFA found in various natural sources including maritime pine (Pinus pinaster) seed oil (MPSO), gymnospermae leaves and seeds, and freshwater gastropods.{14273,14945,14947} A diet containing MPSO lowered HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to diminish cholesterol efflux in vitro.{14273} 5(Z),11(Z),14(Z)-Eicosatrienoic acid methyl ester, when topically applied, reduces inflammatory processes, potentially by displacing arachidonic acid from phospholipid pools and reducing downstream inflammatory products such as PGE2 and LTs.{14946}
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Medchemexpress LLC Poly(2-hydroxyethyl methacrylate) (Mv 300000) | 25249-16-5 | 300000 | 5 G
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Poly(2-hydroxyethyl methacrylate) (Mv 300000) | 25249-16-5 | 300000 | 5 G
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Cayman Chemical 9 Z 11 E 13 EOctadecatrienoic
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A fatty acid agonist of PPARγ; activates PPARγ transcriptional activity in a reporter assay using RAW 264.7 cells at 10 µM; an inhibitor of DNA polymerase α, -β, -γ, -Δ, and -ε (IC50s = 10.7, 13.4, 10.6, 14, and 22 µM, respectively); an inhibitor of topoisomerase I and -II (IC50s = 20 and 5 µM, respectively); reduces the viability of, and induces apoptosis in, MCF-7 breast cancer cells in a concentration-dependent manner; induces ferroptosis in MDA-MB-231 breast cancer cells in an ACSL1-dependent manner; reduces clinical signs of disease in a model of DSS-induced IBD in PPARγ-expressing, but not PPARγ-knockout, mice
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eMolecules 288083-62-5 | 1-(tert-Butoxycarbonyl)-1H-pyrazole-4-carboxylic acid | Combi-Blocks, Inc. | MFCD22681812 | 212.205 | C9H12N2O4 | 95.000 | CC(C)(C)OC(=O)n1cc(cn1)C(O)=O | 1g | 797036018
1-(tert-Butoxycarbonyl)-1H-pyrazole-4-carboxylic acid | Combi-Blocks, Inc. | 288083-62-5 | MFCD22681812 | 212.205 | C9H12N2O4 | 95.000 | CC(C)(C)OC(=O)n1cc(cn1)C(O)=O | 1g | 797036018
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Ambeed AMBEED
5000868159 RAC-BINAP PD G4 1GR
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Ambeed AMBEED
5000868146 ETHYL 2-METHYL-3-NITROPHEN 5GR
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Ambeed AMBEED
5000868494 S-PYRROLIDINE-3-CARBONITRI 1GR
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C(O)=O)[C@@H]1CCCN1C(=O)OC(C)(C)C | 1g | 525043586](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000158895.jpg-250.jpg)
eMolecules 120205-50-7 | N-Boc-dolaproine | Ambeed | MFCD18157735 | 287.356 | C14H25NO5 | 95.000 | CO[C@H]([C@@H](C)C(O)=O)[C@@H]1CCCN1C(=O)OC(C)(C)C | 1g | 525043586
N-Boc-dolaproine | Ambeed | 120205-50-7 | MFCD18157735 | 287.356 | C14H25NO5 | 95.000 | CO[C@H]([C@@H](C)C(O)=O)[C@@H]1CCCN1C(=O)OC(C)(C)C | 1g | 525043586
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Cayman Chemical BIsIndolylmaleImIde V 5mg
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A weak inhibitor of PKC demonstrating an IC50 value >100 µM; blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo with an IC50 value of 8 µM
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Cayman Chemical BIsIndolylmaleImIde IV 25mg
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A cell permeable inhibitor of PKC with IC50 values reported to range from 0.10 to 0.55 µM; designed to be more discriminative than its parent compound, the non-selective PKC inhibitor, staurosporine (Item No. 81590); also inhibits protein kinase A with IC50 values ranging from 2 to 11.8 µM
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Medchemexpress LLC Z-VEID-FMK | 210344-96-0 | 95.0% | 652.71 | 25 MG
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Z-VEID-FMK is a selective and irreversible peptide inhibitor of caspase-6. This compound has been shown to alleviate drug-induced increases in caspase-6 activity, DNA fragmentation, and cell apoptosis.
- Selectively and irreversibly inhibits caspase-6
- Decreases drug-induced caspase-6 activity, apoptosis, and DNA fragmentation
- In vitro study showed reduction in caspase-6 activity, apoptosis, and DNA fragmentation in HepG2 cells
- For research use only
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