Pyrrolidines
Organic heterocyclic compounds that consist of a five-membered ring with four carbon atoms and one nitrogen atom that form a cyclic secondary amine.
Quantity
- (1)
- (295)
- (4)
- (2)
- (4)
- (1)
- (28)
- (3)
- (10)
- (54)
- (1)
- (10)
- (51)
- (3)
- (1)
- (3)
- (3)
- (1)
- (1)
- (3)
- (6)
- (1)
- (2)
- (1)
- (8)
- (1)
- (125)
- (2)
- (14)
- (23)
- (11)
- (4)
- (65)
- (1)
- (1)
- (1)
- (2)
- (234)
- (8)
- (6)
- (6)
- (10)
- (5)
- (1)
- (18)
- (39)
- (9)
- (8)
- (2)
- (1)
Molecular Weight (g/mol)
- (1)
- (1)
- (1)
- (4)
- (12)
- (12)
- (3)
- (5)
- (1)
- (10)
- (35)
- (2)
- (13)
- (1)
- (3)
- (6)
- (7)
- (4)
- (1)
- (7)
- (8)
- (3)
- (8)
- (1)
- (1)
- (2)
- (8)
- (4)
- (2)
- (2)
- (12)
- (9)
- (1)
- (4)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (3)
- (2)
- (6)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (3)
- (2)
- (4)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (3)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (5)
- (5)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (2)
- (10)
- (3)
- (3)
- (4)
- (1)
- (1)
- (1)
- (1)
- (5)
- (2)
- (1)
- (1)
- (3)
- (1)
- (1)
- (7)
- (4)
- (5)
- (1)
- (1)
- (2)
- (1)
- (2)
- (8)
- (2)
- (1)
- (2)
- (2)
- (5)
- (1)
- (2)
- (7)
- (9)
- (1)
- (1)
- (1)
- (5)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (3)
- (1)
- (2)
- (4)
- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (3)
- (2)
- (6)
- (6)
- (4)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (4)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (2)
- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (3)
- (6)
- (1)
- (2)
- (1)
- (1)
- (3)
- (14)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (9)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (5)
- (1)
- (3)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (5)
- (2)
- (4)
- (1)
- (1)
- (1)
- (3)
- (4)
- (8)
- (3)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (11)
- (1)
- (5)
- (1)
- (1)
- (10)
- (1)
- (1)
- (1)
- (4)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (4)
- (3)
- (4)
- (3)
- (1)
- (1)
- (2)
- (5)
- (1)
- (4)
- (1)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (5)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (2)
- (3)
- (2)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (7)
- (1)
- (3)
- (2)
- (1)
- (1)
- (1)
- (4)
- (3)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (11)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (3)
- (2)
- (1)
- (8)
- (2)
- (4)
- (1)
- (1)
- (1)
- (2)
- (5)
- (2)
- (3)
- (1)
- (2)
- (4)
- (1)
- (2)
- (1)
- (4)
- (1)
- (1)
- (4)
- (2)
- (1)
- (3)
- (1)
- (1)
- (10)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (4)
- (3)
- (8)
- (1)
- (2)
- (1)
- (1)
- (3)
- (4)
- (6)
- (1)
- (1)
- (12)
- (2)
- (2)
Percent Purity
- (2)
- (1)
- (1)
- (2)
- (1)
- (9)
- (2)
- (4)
- (2)
- (1)
- (5)
- (2)
- (4)
- (4)
- (15)
- (2)
- (2)
- (3)
- (2)
- (3)
- (9)
- (1)
- (1)
- (33)
- (74)
- (3)
- (33)
- (20)
- (38)
- (13)
- (13)
- (41)
- (5)
- (1)
- (1)
- (11)
- (1)
- (2)
- (1)
- (2)
- (5)
- (3)
- (2)
- (3)
- (5)
- (3)
- (19)
- (49)
- (16)
- (1)
- (177)
- (8)
- (114)
- (2)
- (2)
- (5)
- (1)
- (66)
- (4)
- (3)
Physical Form
- (3)
- (13)
- (248)
- (6)
- (5)
- (1)
- (2)
- (2)
- (5)
- (3)
- (8)
- (3)
- (137)
- (3)
- (4)
- (2)
- (39)
- (4)
- (2)
- (54)
Boiling Point
- (1)
- (2)
- (1)
- (2)
- (2)
- (8)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (4)
- (2)
- (2)
- (1)
- (4)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (4)
- (3)
- (2)
- (4)
- (2)
- (1)
- (1)
- (1)
- (5)
- (4)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (3)
- (2)
- (2)
- (1)
- (1)
- (2)
- (4)
- (1)
- (8)
- (1)
- (5)
- (3)
- (4)
- (2)
- (3)
- (1)
- (2)
- (2)
- (5)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (4)
- (2)
- (1)
- (3)
- (1)
- (1)
- (1)
- (4)
- (3)
- (2)
- (2)
- (1)
- (2)
- (4)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (2)
- (3)
- (2)
- (2)
- (3)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (2)
- (4)
- (1)
- (2)
- (3)
- (2)
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1,186
Medchemexpress LLC (1R,3S)-Compound E | 504428-17-5 | 99.6% | C27H24F2N4O3 | 25 MG
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(1R,3S)-Compound E is an isomer of Compound E (HY-14176) and serves as an experimental control. This compound functions as a γ-secretase inhibitor, effectively blocking the cleavage of β-amyloid (40), β-amyloid (42), and Notch γ-secretase, with IC50 values of 0.24, 0.37, and 0.32 nM respectively.
- Isomer of compound E
- Functions as an experimental control
- Acts as a gamma-secretase inhibitor
- Blocks beta-amyloid (40) cleavage
- Blocks beta-amyloid (42) cleavage
- Blocks notch gamma-secretase cleavage
- IC50 values for cleavage are 0.24, 0.37, and 0.32 nM
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1,187
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000288849 RAC -TBAJ-5307 10MG
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1,188
Medchemexpress LLC 3,6,9,16-Tetraoxaheptadecanoic acid, 17-phenyl-, 1,1-dimethylethyl ester | 2381196-81-0 | 95.8% | 100 MG
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Boc-C1-PEG3-C4-OBn is a PROTAC linker, which refers to the PEG composition. It can be used in the synthesis of various PROTACs. PROTACs consist of two distinct ligands linked by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PROTAC linker with PEG composition
- Can be used in the synthesis of various PROTACs
- Targets an E3 ubiquitin ligase and a protein of interest
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
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1,189
Medchemexpress LLC AZD5582 dihydrochloride | 1883545-51-4 | 99.8% | 1088.21 | 50 MG
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AZD5582 dihydrochloride is an antagonist of the inhibitor of apoptosis proteins (IAPs), binding to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis and is for research use only.
- Binds to BIR3 domains of cIAP1, cIAP2, and XIAP
- Induces apoptosis
- Inhibits cell viability in H1975 NSCLC cells
- Downregulates cIAP-1 and activates RIPK1
- Triggers extrinsic and intrinsic apoptosis pathways
- Causes degradation of cIAP1 and caspase 3 cleavage in tumor cells in vivo
- Leads to substantial tumor regressions in xenograft models
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1,190
Medchemexpress LLC (E/Z)-GSK5182 | 2699724-40-6 | 98.9% | 417.54 | 50 MG
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(E/Z)-GSK5182 is a racemic compound of (E)-GSK5182 and (Z)-GSK5182 isomers. It is a highly selective and orally active inverse agonist of estrogen-related receptor γ (ERRγ) with an IC50 of 79 nM. It also induces reactive oxygen species (ROS) generation in hepatocellular carcinoma.
- Racemic compound.
- Highly selective and orally active.
- Inverse agonist of estrogen-related receptor γ (ERRγ) with an IC50 of 79 nM.
- Induces reactive oxygen species (ROS) generation in hepatocellular carcinoma.
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1,191
Medchemexpress LLC (Rac)-Finerenone ((Rac)-BAY 94-8862) | 1050477-27-4 | 99.66% | 378.42 | 10 MG
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(Rac)-Finerenone ((Rac)-BAY 94-8862) is the racemate of Finerenone. Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with an IC50 of 18 nM. It shows excellent selectivity against glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold).
- Selective nonsteroidal mineralocorticoid receptor antagonist.
- Orally available.
- High selectivity against glucocorticoid, androgen, and progesterone receptors.
- Available as a ready-to-use 10 mM solution in DMSO.
- Good solubility in DMSO (62.5 mg/mL).
- Multiple in vivo dissolution protocols available for experimental flexibility.
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1,192
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000404827 O- 2R 3S 5R -5- 5- 5MG
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1,193
eMolecules ChemScene 1-(tert-Butoxycarbonyl)-3 3-difluoropiperidine-4-carboxylic acid 250mg 346751361 CS-W001386 0 000 1303972-81-7 MFCD18909780 265 257 C11H17F2NO4
ChemScene 1-(tert-Butoxycarbonyl)-3 3-difluoropiperidine-4-carboxylic acid 250mg 346751361 CS-W001386 0 000 1303972-81-7 MFCD18909780 265 257 C11H17F2NO4
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1,194
Ambeed 1 tertButyl 4 1 3dioxoisoindo
1-(tert-Butyl) 4-(1,3-dioxoisoindolin-2-yl) piperidine-1,4-dicarboxylate, 1872262-73-1, 97%
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1,195
Ambeed 4 4Hydroxyphenyl cyclohexanone
4-(4-Hydroxyphenyl)cyclohexanone, 105640-07-1, 95%
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1,196
Ambeed 1 tertButyl 4 1 3dioxoisoindo
1-(tert-Butyl) 4-(1,3-dioxoisoindolin-2-yl) piperidine-1,4-dicarboxylate, 1872262-73-1, 97%
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1,197
Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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5000587571 PAN-KERATIN C11 MOUSE MONOCLON
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1,198
Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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5000587749 PAN-KERATIN C11 MOUSE MONOCLON
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1,199
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000656089 C11 BODIPY 505/515 M 10MG
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1,200
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000656116 C11 BODIPY 505/515 M 50MG
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