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Filtered Search Results
Medchemexpress LLC Boc-NH-PEG6-amine | 1G
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Boc-NH-PEG6-amine | 1G
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Medchemexpress LLC Azido-PEG3-C-Boc | 250MG
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Azido-PEG3-C-Boc | 250MG
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Medchemexpress LLC (R)-1-Boc-3-propylpiperazine | 928025-57-4 | 228.34 | 100 MG
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(R)-1-Boc-3-propylpiperazine is a drug intermediate for synthesis of various active compounds. This product has not been fully validated for medical applications and is for research use only.
- Target: drug intermediate
- Pathway: others
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Medchemexpress LLC DBCO-NH-Boc | 1539290-74-8 | C23H24N2O3 | 50 MG
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DBCO-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Alkyl/ether-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains a DBCO group for strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
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Medchemexpress LLC 5,8,11,14,17,20-hexaoxa-2-azatricosanedioic acid, 1-(1,1-dimethylethyl) ester | 882847-13-4 | >97.0% | 453.52 g/mol | C20H39NO10 | 250 MG
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Boc-NH-PEG6-CH2CH2COOH is a Boc-protected PEG6 linker with a terminal carboxylic acid, supplied for use in synthetic and bioconjugation applications such as PROTAC and ADC linker assembly.
- Boc-protected amine functionality allows orthogonal deprotection
- Peg6 spacer improves solubility and provides flexibility
- Terminal carboxylic acid enables amide coupling chemistry
- High purity (≥97.0%) as determined by NMR
- Available in small research pack sizes (250 MG)
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Medchemexpress LLC Boc-NH-PEG-amine | ≥98.0% | 100 MG
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Boc-NH-PEG-amine (MW 5000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs are compounds that link an E3 ubiquitin ligase ligand to a target protein ligand, utilizing the intracellular ubiquitin-proteasome system for selective degradation of target proteins. This product is for research use only.
- PEG-based linker for PROTAC synthesis.
- Enables the degradation of target proteins.
- Utilizes the intracellular ubiquitin-proteasome system.
- Contains two ligands: E3 ubiquitin ligase and target protein.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 193269-78-2 | 1-BOC-3-Aminoazetidine | Combi-Blocks | MFCD01861753 | 172.228 | C8H16N2O2 | 97.000 | CC(C)(C)OC(=O)N1CC(N)C1 | 10g | 342861562
1-BOC-3-Aminoazetidine | Combi-Blocks | 193269-78-2 | MFCD01861753 | 172.228 | C8H16N2O2 | 97.000 | CC(C)(C)OC(=O)N1CC(N)C1 | 10g | 342861562
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Medchemexpress LLC Recombinant human carbonic anhydrase 9 (His-tag) | >95.0% | 100UG
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Recombinant human carbonic anhydrase 9 (CA9) produced in HEK293 cells and supplied as a lyophilized preparation with a C-terminal 6xHis tag. The protein corresponds to amino acids Q38-D414 of human CA9, is glycosylated (apparent molecular weight 45-60 kDa), and is purified to >95% by reducing SDS-PAGE. It is formulated in PBS (pH 7.4) or PBS with 8% trehalose and intended for research use in biochemical and cell biology studies involving CA9.
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Medchemexpress LLC Carbonic anhydrase 9 protein, cynomolgus (HEK293, His) | 10UG
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Recombinant cynomolgus carbonic anhydrase IX (CA9) expressed in HEK293 cells with a C-terminal His tag. The enzyme catalyzes reversible hydration of CO2 and is supplied as a lyophilized powder from PBS (pH 7.4) with 8% trehalose; reconstitute to ≥100 μg/mL in ddH2O for recommended use. Suitable for biochemical and cell biology studies of pH regulation and CA9-related pathways.
- Recombinant protein expressed in HEK293 cells.
- C-terminal His tag for purification and detection.
- Lyophilized from PBS (pH 7.4) with 8% trehalose for stability.
- Recommended reconstitution concentration ≥100 μg/mL in ddH2O.
- Useful for studies of carbon dioxide transport and pH regulation.
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Medchemexpress LLC Carbonic Anhydrase I Antibody (YA560) | 29 kDa | 100 UL
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The Carbonic Anhydrase I Antibody (YA560) is a laboratory chemical designed for the manufacture of various substances. Provided as a liquid, it exhibits stability under recommended storage conditions, making it suitable for a range of research applications.
- Predicted band size: 29 kDa
- Observed band size: 29 kDa
- Identified for laboratory chemicals and substance manufacturing
- Stable under recommended storage conditions
- Store in a cool, well-ventilated area
- Keep away from direct sunlight and ignition sources
- Keep container tightly sealed
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Boc-NH-PEG-amine (MW 5000) | ≥98.0% | 50 MG
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Boc-NH-PEG-amine (MW 5000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs utilize an intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting a ligand for an E3 ubiquitin ligase and a ligand for the target protein. This product is provided as a solid, white to off-white appearance, with a purity of ≥98.0%. It is intended for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system for selective protein degradation
- Solid, white to off-white appearance
- Purity of ≥98.0%
- Average molecular weight of 5000
- Stable under recommended storage conditions
- Available in various quantities for research
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Br-PEG4-CH2-Boc | 1807505-29-8 | ≥97.0% | 100 MG
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Br-PEG4-CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs utilize two distinct ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other a specific target protein, to facilitate the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- PEG- and alkyl/ether-based linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Facilitates selective degradation of target proteins
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Boc-amido-PEG9-amine | 890091-43-7 | ≥98.0% | C25H52N2O11 | 250 MG
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Boc-amido-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is for research use only and not sold to patients.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- For research use only
- Not for sale to patients
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC N- t-Boc-Aminooxy-PE | 25MG
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N- t-Boc-Aminooxy-PE | 25MG
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Medchemexpress LLC Boc-amido-PEG9-amine | 890091-43-7 | ≥98.0% | C25H52N2O11 | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Boc-amido-PEG9-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are designed with two distinct ligands connected by a linker, one binding to an E3 ubiquitin ligase and the other to a target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- Can be used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- Ligand for an E3 ubiquitin ligase
- Ligand for the target protein
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More