Quinolines and derivatives

Apexbio Technology LLC 10-DAB (10-Deacetylbaccatin) 32981-86-5 200mg

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10-Deacetylbaccatin is a diterpenoid intermediate used as a precursor in the synthesis of chemotherapeutic agents such as paclitaxel and docetaxel It serves as a starting framework for the chemical transformation into taxane-based antitumor compounds 10-Deacetylbaccatin exerts its value primarily through its utility in medicinal chemistry for developing and optimizing cancer therapeutics Based on these properties 10-Deacetylbaccatin holds research potential in the field of cancer drug development

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Medchemexpress LLC Guanidinoethyl sulfonate | 543-18-0 | 99.9% | 167.19 | 50 MG

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Guanidinoethyl sulfonate | 543-18-0 | 99.9% | 167.19 | 50 MG

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Medchemexpress LLC Everolimus | 159351-69-6 | MFCD00929329 | 99.7% | 958.22 g/mol | C53H83NO14 | 200 MG

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Everolimus is a rapamycin-derivative mTORC1 inhibitor used in research to modulate cell growth, proliferation, autophagy, and immune responses. It binds FKBP12 to form an inhibitory complex with mTOR and is commonly used in cellular and preclinical studies.

• Potent, selective mTORC1 inhibitor.
• Binds FKBP12 to form an inhibitory complex with mTOR.
• High purity reported (99.74%).
• Available in multiple research pack sizes up to 100 mg and as a 10 mM solution.
• Intended for research and analytical applications.

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Medchemexpress LLC Quinine sulfate hydrate | 6119-70-6 | 99.97% | 409.48 | 25 G

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Quinine sulfate hydrate is an orally active alkaloid extracted from cinchona bark, primarily used in anti-malarial studies. It also functions as a potassium channel inhibitor, inhibiting WT mouse Slo3 (KCa5.1) channel currents.

• Orally active alkaloid
• Extracted from cinchona bark
• Used in anti-malarial studies
• Potassium channel inhibitor
• Inhibits WT mouse Slo3 (KCa5.1) channel currents
• Inhibits DENV proliferation and reduces viral RNA/protein levels
• Shows tumor-suppressing effects

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eMolecules​ EMOLECULES INC

5000471436 4-CHLORO-3-NITROQUINOLINE 100G

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Apexbio Technology LLC Ranolazine 95635-55-5 200mg

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Ranolazine (CAS 95635-55-5) is a small molecule that acts as an anti-ischemic agent by selectively inhibiting the late sodium current (INaL) in cardiac cells thereby reducing intracellular sodium accumulation and subsequent calcium overload via the Na /Ca2 exchanger This action mitigates adverse effects associated with ischemia-induced ionic imbalance Ranolazine has also been shown to shift ATP production from fatty acid oxidation toward glucose oxidation reflecting greater metabolic efficiency as glucose oxidation yields more ATP per mole of oxygen consumed Additionally it decreases oxygen consumption and suppresses fatty acid-driven ketogenesis in hepatic cells Ranolazine is widely utilized in research focused on myocardial energy metabolism and ischemic heart disease

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Medchemexpress LLC 3-(N-maleimido-propionylamino)-propyl-sulfonic acid sodium salt | 185332-92-7 | MFCD17215919 | 98.8% | 382.28 g·mol⁻¹ | C12H11N2NaO9S | 25 MG

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Sulfo-GMBS is a water-soluble, heterobifunctional cross-linker bearing a sulfo-NHS ester reactive toward primary amines and a maleimide reactive toward sulfhydryl groups. It enables efficient amine-to-thiol conjugation in aqueous buffers for protein and peptide modification, labeling, and cross-linking workflows. The sodium sulfonate improves aqueous solubility for biological applications.

• Water-soluble heterobifunctional cross-linker for amine-to-thiol coupling
• Contains a sulfo-NHS ester reactive toward primary amines
• Contains a maleimide group selective for sulfhydryl groups
• Suitable for conjugation in aqueous buffers and physiological conditions
• High purity supports consistent conjugation performance
• Applicable to protein labeling, cross-linking, and bioconjugation assays

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Chemscene ChemScene | Tacrine | 25G | CS-0035017 | 0.98 | 321-64-2| MFCD00046923 | 198.27

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ChemScene | Tacrine | 25G | CS-0035017 | 0.98 | 321-64-2| MFCD00046923 | 198.27

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Medchemexpress LLC Vk-II-86 (carvedilol analogue) | 955371-84-3 | 93.3% | 420.50 | C25H28N2O4 | 5 MG

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VK-II-86 is a carvedilol analogue and a store-overload-induced calcium release (SOICR) inhibitor used as a research chemical to study cardiac arrhythmia mechanisms and calcium homeostasis. It lacks β-adrenoceptor antagonist activity and has been shown to prevent hypokalaemia-induced ventricular arrhythmia by normalizing ion channel activity and repolarization reserve.

• Inhibits store-overload-induced calcium release, supporting arrhythmia research.
• Lacks β-adrenoceptor antagonist activity, reducing β-blocking confounds in studies.
• Reported to normalize calcium homeostasis and repolarization reserve in models.
• Solid, light brown to brown appearance and supplied in small milligram quantities.
• Molecular weight 420.50 g/mol; formula C25H28N2O4.
• High purity (93.3%) suitable for laboratory research applications.

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