Quinolines and derivatives
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Filtered Search Results
=O | 1g | 205390699](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502187482.JPG-250.jpg)
eMolecules 42606-33-7 | 4-Amino-3-nitroquinoline | Combi-Blocks | MFCD00666909 | 189.174 | C9H7N3O2 | 98.000 | Nc1c(cnc2ccccc12)[N+]([O-])=O | 1g | 205390699
4-Amino-3-nitroquinoline | Combi-Blocks | 42606-33-7 | MFCD00666909 | 189.174 | C9H7N3O2 | 98.000 | Nc1c(cnc2ccccc12)[N+]([O-])=O | 1g | 205390699
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Chemscene ChemScene | 8-Bromo-5-nitroquinoline | 5G | CS-0035507 | 0.98 | 139366-35-1| MFCD00509069 | 253.055
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ChemScene | 8-Bromo-5-nitroquinoline | 5G | CS-0035507 | 0.98 | 139366-35-1| MFCD00509069 | 253.055
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Accela Chembio Inc 5-nitroquinoline | 25g | 607-34-1 | MFCD00006790 | 98% | Shelf Life: 1980 Days | Light Sensitive
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5-nitroquinoline | 25g | 607-34-1 | MFCD00006790 | 98% | Shelf Life: 1980 Days | Light Sensitive
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![Medchemexpress LLC N-(1-benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-yl)-2-phenylacetamide | 365565-02-2 | 99.3% | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000234673.png-250.jpg)
Medchemexpress LLC N-(1-benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-yl)-2-phenylacetamide | 365565-02-2 | 99.3% | 25 MG
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PGP-4008 is a selective P-glycoprotein (Pgp) inhibitor used in research to study multidrug resistance and Pgp-mediated drug transport in cellular and animal models.
- Selective Pgp inhibitor for multidrug resistance research.
- Reported purity approximately 99.3% by primary supplier.
- CAS number 365565-02-2; molecular formula C26H23N3O; molecular weight 393.5 g/mol.
- Typically supplied as a 25 MG solid; soluble in DMSO.
- For research use only; follow appropriate handling and storage.
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Apexbio Technology LLC CP 339818 hydrochloride 50mg
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CP 339818 hydrochloride (CAS 478341-55-8) is a small-molecule antagonist targeting the Kv1 3 potassium channel It is designed to selectively inhibit Kv1 3-mediated ion conductance thereby modulating T-cell activation CP 339818 hydrochloride exerts its biological activity primarily through stabilization of the Kv1 3 channel s C-type inactivation state In in vitro studies CP 339818 hydrochloride demonstrates potent inhibition of Kv1 3 channels with an IC50 value of approximately 200 nM Based on these pharmacological properties CP 339818 hydrochloride holds research potential in the investigation of immune modulation mechanisms relevant to autoimmune and inflammatory disorders
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Medchemexpress LLC CP 339818 hydrochloride | 478341-55-8 | 99.6% | 340.89 | 1 ML
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CP 339818 hydrochloride is a non-peptide blocker of Kv1.3 (IC50 = 200 nM) and Kv1.4 channels. It also inhibits HCN channels with IC50s of 18.9 μM and 43.4 μM against HCN1 and HCN4 (high Cl-), respectively. The compound exhibits significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels. It selectively blocks Kv1.3, which in turn inhibits the activation process of human T cells. CP 339818 hydrochloride can be utilized for studying the physiological functions of HCN and Kv channels. For research use only, not for sale to patients.
- Non-peptide blocker of Kv1.3 and Kv1.4 channels.
- Inhibits HCN1 and HCN4 channels.
- Selectively blocks Kv1.3, inhibiting human T-cell activation.
- Useful for studying physiological functions of HCN and Kv channels.
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Medchemexpress LLC Mefloquine | 53230-10-7 | 100.0% | 378.31 | 5 MG
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Mefloquine is an orally active and potent quinoline antimalarial agent, also functioning as an anti-SARS-CoV-2 entry inhibitor and a K+ channel (KvQT1/minK) antagonist. It is suitable for various research applications.
- Orally active and potent quinoline antimalarial agent.
- Anti-SARS-CoV-2 entry inhibitor.
- K+ channel (KvQT1/minK) antagonist with an IC50 of approximately 1 μM.
- Suitable for malaria research.
- Suitable for systemic lupus erythematosus research.
- Suitable for cancer research.
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Medchemexpress LLC Mefloquine hydrochloride | 51773-92-3 | 99.98% | 414.77 | 1 ML
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Mefloquine hydrochloride | 51773-92-3 | 99.98% | 414.77 | 1 ML
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Medchemexpress LLC Quinine sulfate | 549-56-4 | 97.0% | 100 MG
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Quinine sulfate from MedChemExpress is an antiarrhythmic agent. It acts as a potent, orally active, selective cytochrome P450db inhibitor and a K+ channel blocker with an IC50 of 19.9 μM. It is also used for malaria research.
- Acts as an antiarrhythmic agent.
- Functions as a potent, orally active, selective cytochrome P450db inhibitor.
- Blocks K+ channels with an IC50 of 19.9 μM.
- Suitable for malaria research.
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Medchemexpress LLC Quinidine methiodide | 42982-87-6 | C21H27IN2O2 | 100 MG
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Quinidine methiodide is a metabolite of Quinidine, an established antiarrhythmic agent. This compound is intended for research use only and is not sold to patients.
- Metabolite of quinidine
- Antiarrhythmic agent
- For research purposes
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Medchemexpress LLC Mefloquine | 53230-10-7 | 99.96% | 378.31 | 50 MG
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Mefloquine (Standard) is the analytical standard of Mefloquine, intended for research and analytical applications. It is an orally active and potent quinoline antimalarial agent and an anti-SARS-CoV-2 entry inhibitor. Mefloquine also acts as a K+ channel (KvQT1/minK) antagonist with an IC50 of approximately 1 μM. It can be utilized for malaria, systemic lupus erythematosus, and cancer research.
- Analytical standard of Mefloquine.
- Intended for research and analytical applications.
- Orally active and potent quinoline antimalarial agent.
- Anti-SARS-CoV-2 entry inhibitor.
- K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM.
- Applicable for malaria, systemic lupus erythematosus, and cancer research.
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
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Medchemexpress LLC Mefloquine (Standard) | 53230-10-7 | MFCD00869324 | 378.31 | 100 MG
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Mefloquine (Standard) is the analytical standard of Mefloquine, intended for research and analytical applications. It is an orally active and potent quinoline antimalarial agent and an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. This analytical standard grade compound is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Orally active and potent quinoline antimalarial agent.
- Anti-SARS-CoV-2 entry inhibitor.
- K+ channel (KvQT1/minK) antagonist.
- Used for malaria, systemic lupus erythematosus, and cancer research.
- Analytical standard grade for qualitative, quantitative, and methodological research experiments.
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Medchemexpress LLC Cinchonine | 118-10-5 | MFCD00064372 | 99.7% | 294.39 g/mol | C19H22N2O | 50g
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Cinchonine is a natural compound present in Cinchona bark with antimalarial antitumor anti-inflammatory anti platelet-aggregation and anti-obesity properties Cinchonine inhibits cells proliferation and autophagy and induces apoptosis through activation of Caspase-3 Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells[1]
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AdipoGen Quinine HCl dihydrate
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Chemical. CAS 6119-47-7. Formula C20H24N2O2 . HCl . 2H2O. MW BD9837. Quinine hydrochloride dihydrate is isolated from the cinchona tree?s bark, is characterized by a bitter taste and shows antipyretic fever-reducing, anti-malarial, analgesic painkilling, anti-viral and anti-inflammatory properties. Quinine also possesses, at high concentrations, antibacterial properties, which suggests it has potential as an antimicrobial adjuvant. It is believed to impede the activity of enzymes associated with nucleic acid and protein biosynthesis and act as an antagonist for specific neurotransmitters, including serotonin. Quinine acts as a competitive inhibitor of monoamine oxidase MAO, an enzyme that removes neurotransmitters from the brain and a general potasssium channel blocker. Quinine is a flavor component of tonic water and bitter lemon drink mixers.
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Medchemexpress LLC Mefloquine (hydrochloride) | 51773-92-3 | 99.98% | 414.77 | 500 MG
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Mefloquine hydrochloride is a quinoline antimalarial agent and an anti-SARS-CoV-2 entry inhibitor. It acts as a K+ channel antagonist and is suitable for research in malaria, systemic lupus erythematosus, and cancer. It selectively inhibits prostate cancer cell growth and shows higher anti-SARS-CoV-2 activity than Hydroxychloroquine. Animal studies indicate it can reverse lower vertebral cancellous bone volume.
- Quinoline antimalarial agent
- Anti-SARS-CoV-2 entry inhibitor
- K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM
- Selectively inhibits prostate cancer cell growth with an IC50 of ~10 μM
- Induces hyperpolarization of mitochondrial membrane potential (MMP) and ROS generation
- Shows higher anti-SARS-CoV-2 activity than Hydroxychloroquine
- Can be used for malaria, systemic lupus erythematosus and cancer research
- Reverses lower vertebral cancellous bone volume and bone formation in old mice
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