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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000371872 MPEG-AMINE MW 550 250MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000371881 PRMT5-IN-31 25MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000382468 VII-31 25MG
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Medchemexpress LLC STF-31 | 724741-75-7 | 99.8% | 423.53 | 5 MG
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STF-31 is a selective inhibitor of glucose transporter 1 (GLUT1), with an IC50 of 1 μM. It is also a NAMPT inhibitor and inhibits glucose uptake in renal cell carcinoma (RCC) 4 cells.
- Selective inhibitor of glucose transporter 1 (GLUT1).
- NAMPT inhibitor.
- Inhibits glucose uptake in renal cell carcinoma (RCC) 4 cells.
- Specifically toxic to RCC4 cells at concentrations of 0.01-10 μM, while RCC4/VHL cells are relatively unaffected.
- Causes necrotic cell death and does not induce autophagy, apoptosis, or DNA damage at concentrations of 1.25-5 μM for 3 days.
- Reduces light-induced CX3CR1gfp/+ mice microglial activation and retinal degeneration in vivo at 10 mg/kg.
- Promotes accumulation of necrotic thymocytes after Dexamethasone-induced apoptosis in vivo at 10 mg/kg.
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Medchemexpress LLC Quinine hydrochloride | 130-89-2 | MFCD00078498 | 99.8% | 360.88 | 1 ML
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Quinine hydrochloride is an alkaloid derived from the bark of the cinchona tree, primarily known for its role as an anti-malaria agent. It also functions as a potassium channel inhibitor.
- Acts as an anti-malaria agent
- Inhibits WT mouse Slo3 (KCa5.1) channel currents
- Suitable for laboratory centrifugation and storage
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Medchemexpress LLC 7PPD-Q | 2894124-00-4 | 98.9% | 312.41 | 1 MG
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7PPD-Q is a substituted p-phenylenediamine antioxidant derivative. It has been found to be toxic to the bacterium *V. fischeri* with an EC50 of 14.9 mg/L and is intended for research use only.
- Acts as an antioxidant derivative
- Exhibits toxicity to *Vibrio fischeri* bacterium
- Suitable for research applications
- Available as a solid in pale purple to purple color
- Soluble in DMSO for in vitro studies
- Can be formulated for in vivo studies with DMSO and corn oil
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Medchemexpress LLC Bromopride | 4093-35-0 | 99.5% | 200 MG
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Bromopride | 4093-35-0 | 99.5% | 200 MG
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Medchemexpress LLC Cephalothin | 153-61-7 | 200 MG
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Cephalothin (Standard) is the analytical standard of Cephalothin, intended for research and analytical applications. It is a semi-synthetic cephalosporin and beta-lactam antibiotic. It interferes with the cross-linking of peptidoglycan in the cell wall, hindering bacterial cell wall synthesis. It can be used in hematological and nephrotoxicity studies and is commonly employed in qualitative, quantitative, and methodological research experiments involving HPLC, GC, and MS.
- Analytical standard for research and analytical applications
- Semi-synthetic cephalosporin and beta-lactam antibiotic
- Inhibits class C β-lactamase AmpC
- Interferes with bacterial cell wall synthesis
- Exhibits antibacterial activity against a variety of bacteria
- Suitable for hematological and nephrotoxicity studies
- Used in HPLC, GC, and MS research experiments
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Medchemexpress LLC Mycophenolate mofetil | 128794-94-5 | 99.8% | 200 MG
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Mycophenolate mofetil (RS 61443) is the morpholinoethylester proagent of Mycophenolic acid. It inhibits de novo purine synthesis by inhibiting inosine monophosphate dehydrogenase (IMPDH). Mycophenolate mofetil exhibits selective lymphocyte antiproliferative effects on both T and B cells, which prevents antibody formation.
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Medchemexpress LLC 8-Hydroxyquinoline | 148-24-3 | 99.95% | 1 G
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8-Hydroxyquinoline (8-Quinolinol) is a lipophilic metal chelator used as a fungicide. It demonstrates an MIC range of 27.56-55.11 μM (4-8 μg/mL) against clinical isolates of *Neisseria gonorrhoeae*. The compound binds to copper, forming complexes that facilitate copper transport into cells. It has also been observed to increase micronucleated polychromatic erythrocytes and cause hair depigmentation in mice. This product is for research use only and is not sold to patients.
- Functions as a lipophilic metal chelator and fungicide
- Exhibits activity against *Neisseria gonorrhoeae*
- Binds to copper to facilitate cellular transport
- Increases micronucleated polychromatic erythrocytes in mice
- May cause hair depigmentation in mice
- Induces cytotoxicity in various cell lines
- Inhibits proteasomal chymotrypsin-like activity
- Reduces inflammation by inhibiting NO production and iNOS expression
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Medchemexpress LLC Corticosterone | 50-22-6 | 99.8% | 200 MG
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Corticosterone is an orally active glucocorticoid produced by the adrenal cortex. It is involved in regulating neuronal functions within the limbic system, including the hippocampus, prefrontal cortex, and amygdala.
- Enhances Rab-mediated AMPAR membrane traffic through SGK-induced phosphorylation of GDI.
- Has an immunosuppressive effect by interfering with dendritic cell maturation.
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Medchemexpress LLC Quinidine (15% dihydroquinidine) | 56-54-2 | 98.4% | 50 G
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Quinidine (15% dihydroquinidine) is an antiarrhythmic agent and a potent, orally active, selective cytochrome P450db inhibitor. It also acts as a K+ channel blocker with an IC50 of 19.9 μM and can induce apoptosis. This product is suitable for malaria research and has shown cytotoxicity against MES-SA cells, as well as effects on the PTZ-induced seizure threshold.
- Acts as an antiarrhythmic agent
- Potent, orally active, selective cytochrome P450db inhibitor
- Functions as a K+ channel blocker
- Capable of inducing apoptosis
- Applicable for malaria research
- Exhibits cytotoxicity against MES-SA cells
- Affects PTZ-induced seizure threshold
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Medchemexpress LLC Hydroquinidine | 1435-55-8 | 100.0% | 25 G
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Hydroquinidine, also known as Dihydroquinidine, is a potent ion channel blocker with demonstrated anti-cancer activity against colon, pancreatic, and hepatocellular cancer cells. It is also known to prolong the QT interval and exhibit antiarrhythmic efficacy.
- Potent ion channel blocker
- Demonstrates strong anti-cancer activity on colon, pancreatic, and hepatocellular cancer cells
- Prolongs the QT interval
- Exhibits antiarrhythmic efficacy
- Molecular formula: C20H26N2O2
- Molecular weight: 326.44
- Appearance: White to off-white solid
- For research use only
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Medchemexpress LLC Amikacin hydrate | 1257517-67-1 | MFCD11045969 | 99.9% | 200 MG
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Amikacin hydrate is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. It is bactericidal, inhibiting protein synthesis by acting directly on the 30S and 50S bacterial ribosomal subunits.
- Highly active against most Gram-negative bacteria
- Effective against gentamicin- and tobramycin-resistant strains
- Inhibits infections caused by susceptible Nocardia and nontuberculous mycobacteria
- Treats infections caused by organisms resistant to other aminoglycosides
- Less affected by aminoglycoside-modifying enzymes
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Medchemexpress LLC Imiquimod (hydrochloride) | 99011-78-6 | 99.8% | 500 MG
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Imiquimod hydrochloride is an immune response modifier and a selective toll-like receptor 7 (TLR7) agonist. It demonstrates antiviral and antitumor effects in vivo and is used in research for various conditions, including external genital and perianal warts, cancer, and COVID-19.
- Immune response modifier and selective TLR7 agonist
- Demonstrates antiviral and antitumor effects
- Used in research for external genital, perianal warts, cancer, and COVID-19
- Soluble in DMSO and water
- Can be utilized to induce psoriasis models
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