Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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3,931 – 3,945 of 5,522 results

3,931

Medchemexpress LLC Exendin-3/4 (59-86) Pedin-3/4 (59-86 | 1263874-37-8 | 98.2% | 3055.42 | 5 MG

Exendin-3/4 (59-86) is a derivative of Exendin-4 peptide. Exendin-4 itself is a pure GLP-1 receptor agonist. Exendin-4 peptide derivatives are structurally derived from Exendin-4 and may be related to dual GLP-1/glucagon receptor agonists.

Peptide derivative.
Structurally derived from Exendin-4.
May relate to dual GLP-1/glucagon receptor agonists.
Potential medical use in treating disorders of the metabolic syndrome, including diabetes and obesity.
May help with the reduction of excess food intake.
Shows reduced activity on the GIP receptor, which may lower the risk of hypoglycemia.

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3,932

Medchemexpress LLC Recombinant mouse interleukin-31 | >85.0% | 2 UG

Recombinant mouse interleukin-31 produced in HEK293 cells and supplied as a filtered PBS solution for research applications. The protein is provided as a solution (2 μg vial) with a C-terminal His tag and is characterized by predicted mass and receptor-binding activity suitable for in vitro assays.

Expressed in HEK293 mammalian cells for native folding and glycosylation.
C-terminal His tag facilitates purification and detection.
Predicted molecular mass approximately 17.1 kDa.
Purity greater than 85% as determined by reducing SDS-PAGE.
Demonstrated receptor binding activity (ED50 reported in functional assay).
Supplied in PBS, pH 7.4; store at -80°C and avoid repeated freeze-thaw cycles.

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3,933

Medchemexpress LLC Pyrimido[4,5-d]pyrimidinone derivative (1-cyclobutyl, 2,6-dimethylphenyl, 2-methoxy-4-piperazinyl) | 2172617-15-9 | 99.8% | 100 MG

YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor for research use. It displays low-nanomolar activity against SIK isoforms and is supplied as a purified small-molecule reagent.

Potent SIK inhibition (SIK1 = 6.56 nM, SIK2 = 1.77 nM, SIK3 = 20.5 nM).
High reported purity (approximately 99.8% by HPLC).
Molecular formula C30H37N7O2; molecular weight 527.66 g/mol.
Available in multiple sizes and formats, including milligram quantities and a 10 mM solution in DMSO.
For research use only; not for human or veterinary applications.

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3,934

Sigma Aldrich Fine Chemicals Biosciences Ethyl cinnamate 98 stabili1KG

REAGENT Ethyl cinnamate 98 stabili1KG

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3,935

Medchemexpress LLC PVD-06 | 3032975-48-4 | 98.3% | 1074.13 | 1 MG

PVD-06 is a selective PROTAC PTPN2 degrader with a DC50 of 217 nM. It induces PTPN2 degradation via a VHL-, ubiquitin, and proteasome-dependent pathway. PVD-06 can promote T cell activation and amplify IFN-γ-mediated anticancer activity, making it suitable for investigating PTPN2 in diseases such as leukemia and melanoma.

Selective PROTAC PTPN2 degrader
Induces PTPN2 degradation via VHL-, ubiquitin, and proteasome-dependent pathway
Promotes T cell activation
Amplifies IFN-γ-mediated anticancer activity
Composed of a PTPN2 ligand, a linker, and a VHL ligand

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3,936

Medchemexpress LLC Ro 31-9790 (GI4747) | 145337-55-9 | 99.4% | 315.41 g/mol | C15H29N3O4 | 25 MG

Ro 31-9790 is a synthetic metalloproteinase (MMP) inhibitor used in research to block proteolytic shedding of cell-surface molecules such as L-selectin and TNF-α. It demonstrates sub-micromolar to low-micromolar activity in human and mouse immune cells and is supplied as a high-purity solid for laboratory experiments.

Potent inhibition of L-selectin shedding in immune cells.
Active against TNF-α shedding in monocytes.
High purity suitable for biochemical and cellular assays.
Available in multiple pack sizes including small-milligram quantities.
Provided with datasheet, SDS, and COA for quality traceability.

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3,937

Medchemexpress LLC hsa-miR-31-5p mimic 5nmol | 5nmol

hsa-miR-31-5p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity

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3,938

Selleck Chemical LLC Cilostazol 100mg 73963-72-1 OPC-13013

Cilostazol (OPC-13013) is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 ?M and inhibitor of adenosine uptake. *For Research & Development use only. Product is not intended for drug, household, or human consumption.

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3,939

Medchemexpress LLC hsa-miR-31-5p mimic 20nmol | 20nmol

hsa-miR-31-5p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity

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3,940

Medchemexpress LLC 4-((3-((R)-3-(3,4-Dimethoxyphenyl)-1-(((S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carbonyl)oxy | 1092369-24-8 | MFCD31631580 | 99.6% | 624.72 g·mol⁻¹ | C34H44N2O9 | 50 MG

SLF-amido-C2-COOH is a synthetic FKBP12-binding ligand used as a PROTAC building block. It couples an SLF recognition motif to a short linker ending in a carboxylic acid, providing a convenient functional handle for conjugation in bifunctional degrader synthesis.

Acts as an FKBP12-binding moiety for PROTAC construction.
Provides a carboxylic acid handle for amide or ester coupling.
Compatible with standard small-molecule coupling chemistries.
High purity suitable for research applications (≈99.6%).
Molecular formula C34H44N2O9; molecular weight 624.72 g·mol⁻¹.
Supplied as an off-white to white solid for synthetic use.

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3,941

eMolecules 79025-28-8 | 3,4-Dimethoxy-2-nitrobenzoic acid | Combi-Blocks | MFCD00074884 | 227.172 | C9H9NO6 | 95.000 | COc1ccc(C(O)=O)c(c1OC)[N+]([O-])=O | 250mg | 517090861

3,4-Dimethoxy-2-nitrobenzoic acid | Combi-Blocks | 79025-28-8 | MFCD00074884 | 227.172 | C9H9NO6 | 95.000 | COc1ccc(C(O)=O)c(c1OC)[N+]([O-])=O | 250mg | 517090861

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3,942

Medchemexpress LLC 7,4'-Dihydroxyflavone | 2196-14-7 | MFCD00017694 | 1 ML

7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated from *Glycyrrhiza uralensis*. It acts as an eotaxin/CCL11 inhibitor and a CBR1 inhibitor with an IC50 of 0.28 μM. This compound can consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production.

Inhibits MUC5AC gene expression
Reduces mucus production and secretion
Regulates NF-κB, STAT6, and HDAC2 pathways
Decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with an IC50 value of 1.4 μM

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3,943

TARGETMOL CHEMICALS INC KRM-III 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. KRM-III is an orally active T cell antigen receptor (TCR) inhibitor with anti-inflammatory activity that potently inhibits TCR and myristate acetate/fosfomycin/ionomycin-induced NFAT nuclear factor activation and T cell proliferation with an IC50 of approximately 5 uM. purity: 99%

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3,944

eMolecules 1612792-88-7 | potassium;[trans-2-ethoxycarbonylcyclopropyl]-trifluoro-boranuide | Pharmablock440.080 | C12H18B2F6K2O4 | 0.000 | [K+].[K+].CCOC(=O)[C@H]1C[C@@H]1[B-](F)(F)F.CCOC(=O)[C@@H]1C[C@H]1[B-](F)(F)F | 25mg | 812213418

potassium;[trans-2-ethoxycarbonylcyclopropyl]-trifluoro-boranuide | Pharmablock | 1612792-88-7440.080 | C12H18B2F6K2O4 | 0.000 | [K+].[K+].CCOC(=O)[C@H]1C[C@@H]1[B-](F)(F)F.CCOC(=O)[C@@H]1C[C@H]1[B-](F)(F)F | 25mg | 812213418

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3,945

TARGETMOL CHEMICALS INC NOTHOFAGIN 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Nothofagin has antioxidant and antithrombotic activities it possesses anti-inflammatory activity by inhibiting hyperpermeability expression of CAMs and adhesion and migration of leukocytes thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. purity: 99%

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Quinolines and derivatives

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Medchemexpress LLC Exendin-3/4 (59-86) Pedin-3/4 (59-86 | 1263874-37-8 | 98.2% | 3055.42 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Recombinant mouse interleukin-31 | >85.0% | 2 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pyrimido[4,5-d]pyrimidinone derivative (1-cyclobutyl, 2,6-dimethylphenyl, 2-methoxy-4-piperazinyl) | 2172617-15-9 | 99.8% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC PVD-06 | 3032975-48-4 | 98.3% | 1074.13 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ro 31-9790 (GI4747) | 145337-55-9 | 99.4% | 315.41 g/mol | C15H29N3O4 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC hsa-miR-31-5p mimic 5nmol | 5nmol Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC hsa-miR-31-5p mimic 20nmol | 20nmol Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 7,4'-Dihydroxyflavone | 2196-14-7 | MFCD00017694 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More