Quinolines and derivatives
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TARGETMOL CHEMICALS INC TT-10 5MG
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502693731 TT-10 5MG
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Apexbio Technology LLC MLN8054 869363-13-3 200mg
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MLN8054 (CAS 869363-13-3) is a small-molecule inhibitor targeting Aurora A kinase (AAK) It exhibits ATP-competitive reversible inhibition and demonstrates high selectivity for AAK with an IC50 of 4 nM showing 40-fold and 100-fold greater selectivity over Aurora B kinase and other kinases respectively In cellular studies MLN8054 impairs AAK function leading to inactivation of the protein Pt288 disruption of mitotic spindle formation G2/M phase cell cycle arrest and induction of apoptosis In preclinical tumor xenograft models MLN8054 has demonstrated antitumor activity This compound is widely utilized in research focused on cell cycle regulation mitosis and the therapeutic targeting of cancer
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TARGETMOL CHEMICALS INC FLUDIOXONIL 5MG
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502694041 FLUDIOXONIL 5MG
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Apexbio Technology LLC Indoximod (NLG-8189) 110117-83-4 200mg
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Indoximod (NLG-8189 CAS 110117-83-4) is an orally bioavailable small molecule that targets the indoleamine 2 3-dioxygenase (IDO) pathway a key regulator of tryptophan metabolism involved in tumor-mediated immune suppression By blocking IDO activity indoximod reduces the expansion of regulatory T cells (Tregs Foxp3 /CD4 /CD25 ) thereby attenuating tumor-associated immune tolerance Preclinical studies have demonstrated that indoximod enhances adaptive immune responses to antigens and dendritic cell vaccines and its combination with chemotherapeutics such as docetaxel has shown increased toxicity without reaching a maximum tolerated dose at 2000 mg twice daily Indoximod serves as a valuable tool in investigating immunoregulatory mechanisms and immunotherapy strategies in cancer research
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![eMolecules Medchem Express / cis-910-Epoxystearic acid / 5mg / 495800438 / HY-129554 / / 24560-98-3 / [null] / 596.934 / C36H68O6](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502455498.PNG-250.jpg)
eMolecules Medchem Express / cis-910-Epoxystearic acid / 5mg / 495800438 / HY-129554 / / 24560-98-3 / [null] / 596.934 / C36H68O6
Medchem Express / cis-910-Epoxystearic acid / 5mg / 495800438 / HY-129554 / / 24560-98-3 / [null] / 596.934 / C36H68O6
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Medchemexpress LLC 2-quinolinecarboxaldehyde, 8-hydroxy- | 14510-06-6 | MFCD00168962 | 98.0% | 173.17 g/mol | C10H7NO2 | 1 G
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8-Hydroxyquinoline-2-carbaldehyde is an organic biochemical reagent (C10H7NO2, MW 173.17 g/mol) used as a building block in organic synthesis and as a ligand in coordination and analytical chemistry. It is supplied as a solid powder in laboratory pack sizes for research applications, with batch-specific certificates of analysis available for quality confirmation.
- Acts as a building block for organic synthesis.
- Functions as a bidentate ligand and chelating agent.
- Suitable for analytical and proteomics applications.
- Provided in small pack sizes appropriate for laboratory research.
- Batch-specific certificate of analysis available for purity verification.
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TARGETMOL CHEMICALS INC TN1 5MG
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502694092 TN1 5MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000394273 8R 9S -TALAZOPARIB 200MG
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TARGETMOL CHEMICALS INC Desloratadine 200MG
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Also available in 1 g, 1 mL, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Desloratadine (Sch34117) is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smooth muscle, capillaries and gastrointestinal smooth muscle, including vasodilation, bronchoconstriction, increased vascular permeability, pain, itching and spasmodic contractions of gastrointestinal smooth muscle. Desloratadine is used to provide symptomatic relieve of allergic symptoms. Purity 100%
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431154 MHI-148 50MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431224 SULFO-CY7.5 MALEIMID 5MG
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Apexbio Technology LLC TDZD-8 327036-89-5 200mg
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TDZD-8 (CAS 327036-89-5) is a selective non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3 ) exhibiting an IC50 of 1 4 M In addition to GSK-3 TDZD-8 also inhibits protein kinase C isoforms PKC I and PKC with IC50 values of 1 4 M and 1 1 M respectively Cellular studies have demonstrated that TDZD-8 suppresses both GSK-3 and PKC activity leading to reduced photodynamic therapy-induced neuronal necrosis and glial cell apoptosis Furthermore TDZD-8 has been shown to exert anti-leukemic effects in primary human leukemia cell models possibly through dual inhibition of PKC and FLT3 highlighting its utility in studies related to neuroprotection and leukemia
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Selleck Chemical LLC STF-31
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STF-31 is a selective glucose transporter GLUT1 inhibitor
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eMolecules Methyl 1,2,3,4-tetrahydroquinoline-2-carboxylate, HCl | 78348-26-2 | MFCD02180877 | 1g
Combi-Blocks | Methyl 1,2,3,4-tetrahydroquinoline-2-carboxylate, HCl | 1g | 388720995 | ST-9340 | 97.000 | 78348-26-2 | MFCD02180877 | 227.690 | C11H14ClNO2
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Cambridge Isotope Laboratories 1 2 3 4 6 7-HexaCN (PCN-66) (unlabeled) 100 ug/mL in nonane 1 mL
1 2 3 4 6 7-HexaCN (PCN-66) (unlabeled) 100 ug/mL in nonane 1 mL
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