Quinolines and derivatives

Quinaldic Acid 98.0+%, TCI America™

CAS: 93-10-7 Molecular Formula: C10H7NO2 Molecular Weight (g/mol): 173.17 MDL Number: MFCD00006752 InChI Key: LOAUVZALPPNFOQ-UHFFFAOYSA-N Synonym: quinaldic acid,2-quinolinecarboxylic acid,quinaldinic acid,2-carboxyquinoline,quinaldate,2-quinolinylcarboxylic acid,2-quinoline carboxylic acid,2-quinolinecarboxylate,2-quinaldic acid,2-quinolinecarbocylic acid PubChem CID: 7124 ChEBI: CHEBI:18386 IUPAC Name: quinoline-2-carboxylic acid SMILES: OC(=O)C1=CC=C2C=CC=CC2=N1

4-(Bromomethyl)-2-quinolinone 97.0+%, TCI America™

CAS: 4876-10-2 Molecular Formula: C10H8BrNO Molecular Weight (g/mol): 238.08 MDL Number: MFCD03426152 InChI Key: BBAHJCUCNVVEQU-UHFFFAOYSA-N Synonym: 4-bromomethyl-1,2-dihydroquinoline-2-one,4-bromomethyl quinolin-2 1h-one,4-bromomethyl-2 1h-quinolinone,4-bromomethyl-1,2-dihydroquinolin-2-one,4-bromomethyl-1h-quinolin-2-one,2 1h-quinolinone, 4-bromomethyl,4-bromomethyl-2-quinolinone,2-hydroxy-4-bromo methyl quinoline,4-bromomethyl hydroquinolin-2-one,4-bromomethylquinolinon PubChem CID: 268296 IUPAC Name: 4-(bromomethyl)-1H-quinolin-2-one SMILES: C1=CC=C2C(=C1)C(=CC(=O)N2)CBr

9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid 98.0+%, TCI America™

CAS: 82419-35-0 Molecular Formula: C13H9F2NO4 Molecular Weight (g/mol): 281.215 MDL Number: MFCD00226106 InChI Key: NVKWWNNJFKZNJO-UHFFFAOYSA-N Synonym: 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7h-pyrido 1,2,3-de-1,4-benzoxazine-6-carboxylic acid,ofloxacin q acid,oxygen-fluorine acid,9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7h-1,4 oxazino 2,3,4-ij quinoline-6-carboxylic acid,s---9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7h-pyrido-1,2,3-de-1,4-benzoxazine-6-carboxylic acid,9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7h-pyrido 1,2,3-de-1,4-benzoxazine-6-carboxyllic acid,9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido 1,2,3-de 1,4 benzoxazine-6-carboxylic acid,levofloxacin related compound b,ofloxacin q acid, +/-,6,7-difluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo 7.3.1.0?, 1 3 trideca-5 13 ,6,8,11-tetraene-11-carboxylic acid PubChem CID: 534278 SMILES: CC1COC2=C3N1C=C(C(=O)C3=CC(=C2F)F)C(=O)O

Ethyl 7-Chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate 98.0+%, TCI America™

CAS: 100491-29-0 Molecular Formula: C17H10ClF3N2O3 Molecular Weight (g/mol): 382.723 MDL Number: MFCD01863285 InChI Key: JLSXYCZRMYCIMY-UHFFFAOYSA-N Synonym: ethyl 7-chloro-1-2,4-difluorophenyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate,ethyl 7-chloro-1-2,4-difluorophenyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylate,7-chloro-1-2,4-difluorophenyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid ethyl ester,7-chloro-1-2,4-difluoro-phenyl-6-fluoro-4-oxo-1,4-dihydro-1,8 naphthyridine-3-carboxylic acid ethyl ester,ethyl 1-2,4-difluorophenyl-7-cl-6-f-4-o-hydropyridino 2,3-b pyridine-3-carboxylate,7-chloro-6-fluoro-1-2,4-difluorophenyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid ethyl ester,ethyl 1-2,4-difluorophenyl-7-chloro-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate,ethyl 1-2,4-difluorophenyl-7-chloro-6-fluoro-4-oxohydropyridino 2,3-b pyridi ne-3-carboxylate,ethyl 1-2,4-difluorophenyl-7-chloro-6-fluoro-4-oxopyridino 2,3-b pyridine-3-carboxylate,ethyl 7-chloro-1-2,4-difluorophenyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate PubChem CID: 1268243 IUPAC Name: ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylate SMILES: CCOC(=O)C1=CN(C2=NC(=C(C=C2C1=O)F)Cl)C3=C(C=C(C=C3)F)F

Ofloxacin 98.0+%, TCI America™

CAS: 82419-36-1 Molecular Formula: C18H20FN3O4 Molecular Weight (g/mol): 361.373 MDL Number: MFCD00226105 InChI Key: GSDSWSVVBLHKDQ-UHFFFAOYSA-N Synonym: ofloxacin,ofloxacine,floxin,tarivid,oxaldin,ofloxacino,ofloxacinum,ocuflox,oflocet,visiren PubChem CID: 4583 ChEBI: CHEBI:7731 SMILES: CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O

Levofloxacin Q-Acid 98.0+%, TCI America™

CAS: 100986-89-8 Molecular Formula: C13H9F2NO4 Molecular Weight (g/mol): 281.215 MDL Number: MFCD04039905 InChI Key: NVKWWNNJFKZNJO-YFKPBYRVSA-N Synonym: levofloxacin q-acid,levofloxacin carboxylic acid,s-9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2h-1,4 oxazino 2,3,4-ij quinoline-6-carboxylic acid,unii-08gt8fy84e,levofloxacin related compound b,levofloxacin acid,3s-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7h-pyrido 1,2,3-de-1,4-benzoxazine-6-carboxylic acid,levofloxacin q-acid,-,s-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido 1,2,3-de-1,4-benzoxazine-6-carboxylic acid,levofloxacin related compound b usp PubChem CID: 688333 SMILES: CC1COC2=C3N1C=C(C(=O)C3=CC(=C2F)F)C(=O)O

AARON CHEMICALS LLC 4-METHYL-2-HYDROXYQUINOLINE 10

NC3827142 4-METHYL-2-HYDROXYQUINOLINE 10

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Medchemexpress LLC Quinoline-2-carboxaldehyde | 5470-96-2 | 157.17 | 10 G

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Quinoline-2-carboxaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is for research use only and not sold to patients.

• Purity of 99.99%
• Molecular formula C10H7NO
• Molecular weight 157.17
• Storage at -20°C, sealed, away from moisture
• Appearance as a light yellow to yellow solid
• Melting point 66-71°C
• Boiling point 314.3°C at 760 mmHg
• Flash point 151.9°C

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Medchemexpress LLC Quinoline-2-carboxylic acid | 93-10-7 | 173.17 | 50 G

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Quinoline-2-carboxylic acid exhibits antidiabetic activity and can be used as a drug intermediate for the synthesis of various active compounds. It reduces the intestinal absorption of carbohydrates by inhibiting α-glucosidase and α-amylase (IC50 are 9.1 μg/mL and 15.5 μg/mL, respectively), thereby lowering postprandial blood glucose levels. This compound can also be used as a drug intermediate for the synthesis of compounds with antiallergic, apoptosis-inducing, or antiproliferative activities.

• Exhibits antidiabetic activity by reducing intestinal carbohydrate absorption.
• Inhibits α-glucosidase and α-amylase.
• Can be used as a drug intermediate for synthesis of compounds with antiallergic, apoptosis-inducing, or antiproliferative activities.
• Acts as a human endogenous metabolite.

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Medchemexpress LLC Cinchonidine | 485-71-2 | 99.6% | 294.39 | 10 G

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Cinchonidine (α-Quinidine) is a cinchona alkaloid found in *Cinchona officinalis* and *Gongronema latifolium*. It is a building block used in asymmetric synthesis in organic chemistry. It acts as a weak inhibitor of serotonin transporter (SERT) and exhibits antimalarial activities.

• Source: Cinchona alkaloid found in *Cinchona officinalis* and *Gongronema latifolium*.
• Application: Building block in asymmetric synthesis in organic chemistry.
• Biological activity: Weak inhibitor of serotonin transporter (SERT).
• Pharmacological effect: Antimalarial activities.
• Appearance: Solid, white to off-white.
• Storage: Room temperature for continental US shipping; 4°C, protected from light, stored under nitrogen.

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Medchemexpress LLC 2-Hydroxyquinoline | 59-31-4 | 145.16 | 10 G

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2-Hydroxyquinoline is an inhibitor of α-glucosidase and α-amylase with IC50 values of 64.4 μg/mL and 130.5 μg/mL, respectively. It can be used in the study of diabetes. This product is for research use only and has not been fully validated for medical applications.

• Inhibitor of α-glucosidase and α-amylase
• Suitable for diabetes studies
• High purity product

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Medchemexpress LLC 2-Aminoquinoline | 580-22-3 | 144.17 | 10 G

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2-Aminoquinoline (2-Quinolinamine) is a compound that shows promise as a bioavailable neuronal nitric oxide synthase (nNOS) inhibitor. It also exhibits antiviral activity against the vaccinia virus, making it a potential subject for research into antineurodegenerative agents.

• Functions as a bioavailable nNOS inhibitor
• Demonstrates antiviral activity against vaccinia virus
• Useful for research into antineurodegenerative agents
• Has a purity of 99.95%

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Medchemexpress LLC Quinidine (15% dihydroquinidine) | 56-54-2 | >98.36% | 10 G

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Quinidine (15% dihydroquinidine) is an antiarrhythmic agent. It acts as a potent, orally active, and selective cytochrome P450db inhibitor. Additionally, Quinidine is a K+ channel blocker with an IC50 of 19.9 μM and is capable of inducing apoptosis. This compound can also be utilized for malaria research.

• Antiarrhythmic agent.
• Potent, orally active, selective cytochrome P450db inhibitor.
• K+ channel blocker with an IC50 of 19.9 μM.
• Can induce apoptosis.
• Used for malaria research.

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Medchemexpress LLC Quinine hydrochloride | 130-89-2 | 99.8% | 360.88 | 10 MG

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Quinine hydrochloride is an alkaloid derived from the bark of the cinchona tree, acting as an anti-malaria agent and potassium channel inhibitor. It inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV.

• Acts as an anti-malaria agent.
• Functions as a potassium channel inhibitor.
• Inhibits WT mouse Slo3 (KCa5.1) channel currents.

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Medchemexpress LLC Quinoline-6-carboxylic acid | 10349-57-2 | 173.17 | 10 G

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Quinoline-6-carboxylic acid is a biochemical reagent. It can be used as a biological material or organic compound for life science related research.

• Used as a biological material or organic compound
• Suitable for life science related research
• Reagent for biochemical assays
• Solid appearance
• Off-white to light brown in color

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