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Tetrahydroisoquinolines

Organic heterocyclic compounds that consist of an isoquinoline ring with no double bonds; contains a benzene ring fused to a six-membered ring with one nitrogen atom and five carbon atoms.
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Keyword Search:
106 – 120 of 295 results
106

Medchemexpress LLC 1(2H)-isoquinolinone, 5-hydroxy | 5154-02-9 | MFCD00006900 | 99.1% | 161.16 g/mol | C9H7NO2 | 10 MG
SDP

1,5-Isoquinolinediol is a small-molecule PARP inhibitor used in research to modulate DNA repair and oxidative-stress pathways. It exhibits potent PARP inhibition and has been reported to reduce diabetes-induced NADPH oxidase-derived oxidative stress in retinal models. The compound is provided as a solid with high purity and is typically prepared in DMSO for in vitro and in vivo studies.

  • Potent PARP inhibition (IC50 0.18-0.37 μM).
  • Attenuates NADPH oxidase-derived oxidative stress in retinal models.
  • High purity suitable for biochemical and cell-based assays.
  • Soluble in DMSO (≈37 mg/mL) for convenient stock preparation.
  • Stable as a powder when stored cold for extended periods.
  • Applicable for studies of DNA repair, oxidative stress, and cell death pathways.

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107

eMolecules​ 35556-81-1 | 6-Methoxy-1,2,3,9-tetrahydro-carbazol-4-one | J & W PharmLab LLC | MFCD11168368 | 215.252 | C13H13NO2 | 96.000 | COc1ccc2[nH]c3CCCC(=O)c3c2c1 | 5g | 289352484

6-Methoxy-1,2,3,9-tetrahydro-carbazol-4-one | J & W PharmLab LLC | 35556-81-1 | MFCD11168368 | 215.252 | C13H13NO2 | 96.000 | COc1ccc2[nH]c3CCCC(=O)c3c2c1 | 5g | 289352484

ENCOMPASS_PREFERRED
108

eMolecules​ 20315-68-8 | 6-METHOXY-2,3,4,9-TETRAHYDRO-1H-PYRIDO[3,4-B]INDOLE | MFCD00012071 | 5g

Ambeed | N-(234-Trifluorophenyl)acetamide | 250mg | 682932097 | A844755 | 365-29-7 | MFCD01935687 | 189.137 | C8H6F3NO

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109

Medchemexpress LLC HY-19741 10mg Medchemexpress, A-1331852 CAS:1430844-80-6 Purity:>98%
SDP

Medchemexpress, HY-19741 10mg A-1331852 CAS:1430844-80-6 A-1331852 is an orally available BCL-XL selective inhibitor with a Ki of less than 10 pM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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110

eMolecules​ 497251-60-2 | 5,6,7,8-Tetrahydroisoquinolin-8-amine | Combi-Blocks | MFCD08235025 | 148.209 | C9H12N2 | 95.000 | NC1CCCc2ccncc12 | 1g | 267186083

5,6,7,8-Tetrahydroisoquinolin-8-amine | Combi-Blocks | 497251-60-2 | MFCD08235025 | 148.209 | C9H12N2 | 95.000 | NC1CCCc2ccncc12 | 1g | 267186083

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111

eMolecules​ 1229224-93-4 | (R)-N-[1-(5,6,7,8-Tetrahydronaphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-propylamine | Synthonix - Stock | MFCD28167920 | 361.452 | C22H26F3N | 95.000 | C[C@@H](NCCCc1cccc(c1)C(F)(F)F)c1cccc2CCCCc12 | 1g | 495882236

(R)-N-[1-(5,6,7,8-Tetrahydronaphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-propylamine | Synthonix - Stock | 1229224-93-4 | MFCD28167920 | 361.452 | C22H26F3N | 95.000 | C[C@@H](NCCCc1cccc(c1)C(F)(F)F)c1cccc2CCCCc12 | 1g | 495882236

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112

eMolecules​ 40493-18-3 | 4-Chloro-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d] -pyrimidine | Oakwood Chemical | MFCD00463624 | 224.710 | C10H9ClN2S | 0.000 | Clc1ncnc2sc3CCCCc3c12 | 25g | 537679271

4-Chloro-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d] -pyrimidine | Oakwood Chemical | 40493-18-3 | MFCD00463624 | 224.710 | C10H9ClN2S | 0.000 | Clc1ncnc2sc3CCCCc3c12 | 25g | 537679271

ENCOMPASS_PREFERRED
113

eMolecules​ 522-97-4 | Medchem Express | Tetrahydroberberine | 5mg | 446275549 | HY-N0925 | MFCD00067284 | 339.391 | C20H21NO4

Medchem Express | Tetrahydroberberine | 5mg | 446275549 | HY-N0925 | 522-97-4 | MFCD00067284 | 339.391 | C20H21NO4

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114

eMolecules​ 518-34-3 | Tetrandrine | Chem-Impex622.762 | C38H42N2O6 | 98.000 | COc1ccc2CC3N(C)CCc4cc(OC)c(OC)c(Oc5cc6C(Cc7ccc(Oc1c2)cc7)N(C)CCc6cc5OC)c34 | 5g | 510432107

Tetrandrine | Chem-Impex | 518-34-3622.762 | C38H42N2O6 | 98.000 | COc1ccc2CC3N(C)CCc4cc(OC)c(OC)c(Oc5cc6C(Cc7ccc(Oc1c2)cc7)N(C)CCc6cc5OC)c34 | 5g | 510432107

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115

Medchemexpress LLC TCS-OX2-29 | 372523-75-6 | 99.6% | 397.51 g/mol | C23H31N3O3 | 25 MG
SDP

TCS-OX2-29 is a potent, selective orexin-2 receptor (OX2R) antagonist used in neuropharmacology research to probe orexin signaling and sleep-wake regulation. Reported activity includes an IC50 of 40 nM and a pKi of 7.5, with approximately 250-fold selectivity for OX2 over OX1. The compound is supplied as a high-purity solid and is available in DMSO solution formats for easy reconstitution.

  • Potent OX2R antagonist with IC50 ≈ 40 nM.
  • High selectivity for OX2 over OX1 (~250-fold).
  • High purity suitable for research applications (≈99.6%).
  • Available as a solid and as 10 mM DMSO solution for reconstitution.
  • Molecular weight 397.51 g/mol; molecular formula C23H31N3O3.

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116

Ambeed AMBEED

5000892499 15-ISOQUINOLINEDIOL 50MG

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117

Medchemexpress LLC HY-15477A 10mg Medchemexpress, YS-49 (monohydrate) CAS: Purity:>98%
SDP

Medchemexpress, HY-15477A 10mg YS-49 (monohydrate) CAS: YS-49 (monohydrate) is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. YS-49 inhibits angiotensin II (Ang II) -stimulated proliferation of VSMCs via induction of heme oxygenase (HO)-1. YS-49 is also an isoquinoline compound alkaloid, has a strong positive inotropic action through activation of cardiac β-adrenoceptors [1] [2] [3] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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118

Selleck Chemical LLC Tetrabenazine (Xenazine) S1789-10mg
SDP

Tetrabenazine(Xenazine Ro 1-9569) acts primarily as a reversible high-affinity inhibitor of mono-amine uptake into granular vesicles of presynaptic neurons by binding selectively to VMAT-2 Also blocks dopamine D2 receptors but this affinity is 1 000-fold lower than its affinity for VMAT-2

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119

Selleck Chemical LLC Solifenacin (YM905) S5238-25mg
SDP

Solifenacin (YM905) is a competitive muscarinic receptor antagonist The binding of acetylcholine to these receptors particularly the M3 receptor subtype plays a critical role in the contraction of smooth muscle

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120

eMolecules​ 1199782-93-8 | ChemScene | 7-Bromo-1234-tetrahydronaphthalen-1-amine hydrochloride | 100mg | 569145785 | CS-0101640 | MFCD08544186 | 262.58 | C10H13BrClN

Ambeed | 2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone | 250mg | 624119886 | A100260 | 126581-65-5 | MFCD03094564 | 233.036 | C8H6BrFO2

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