Tetrapyrroles and derivatives
Abcam SB431542, ALK inhibitor, 1MG
MW 384.4 Da, Purity >99%. Potent and selective inhibitor of Activin Like Kinase. Inhibits ALK 4, 5 (IC₅₀ = 94 nM), and 7.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Rebo x etine mesylate, Noradrenaline reuptake inhibitor, 50MG
MW 409.5 Da, Purity >99%. Potent, selective noradrenaline reuptake inhibitor, with high selectivity over dopamine and 5-HT transporters. Antidepressant in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam x estospongin C, IP3 receptor antagonist, 10UG
MW 446.72 g/mol, Purity >90%. Potent, selective, reversible IP₃ receptor antagonist (IC₅₀ = 350 nM). Inhibits IP₃-mediated Ca²+ release from ER and SR. 30-Fold selectivity over ryanodine receptor. Inhibits voltage-dependent Ca²+ and K+ channels at higher concentrations. Cell-permeable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Nocodazole, Microtubule inhibitor, 50MG
MW 301.32 Da, Purity >98%. Microtubule inhibitor. Rapidly depolymerises microtubules in vivo and inhibits tubulin polymerisation in vitro. Inhibits mitosis. Also reduces stem cell pluripotency factors Oct 4 and Nanog.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences 5,10,15,20-Tetraphenyl-21H,23H-porphine 97% | 917-23-7 | MFCD00011680 | 25G
5,10,15,20-Tetraphenyl-21H,23H-porphine 97% | Purity: 97% | Mol Wt: 614.74 | 917-23-7 | MFCD00011680 | 25G
Abcam 5-Aza-2'-deo x ycytidine (Decitabine), DNMT1 inhibitor, 25MG
MW 228.21 Da, Purity >99%. Potent DNA methyltransferase 1 (DNMT1) inhibitor (IC₅₀ = 0.2 μM). Incorporated into DNA, inhibits DNMT1 activity to induce DNA hypomethylation. Interferes with protein synthesis. Shows antimetabolic and anticancer activities in vitro. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam UDP-glucose, Highly P2Y14 agonist, 100MG
MW 610.27 Da. Highly potent, endogenous P2Y14 agonist (EC50 = 82 nM). Involved in modulation of gastric function. UDP also available (ab120383).
The product is subject to the following: Abcam Restricted Use Statement
Abcam WAY-100635 maleate, 5-HT1A receptor antagonist, 10MG
MW 538.6 Da, Purity >98%. Potent, selective, silent 5-HT1A receptor antagonist (IC50 = 1.35 nM). Displays >100-fold selectivity for 5-HT1Arelative to a range of other CNS receptors including other 5-HT subtypes, adrenoceptors, dopamine, GABA, histamine and ion channels. Binds selectively to rodent brain 5-HT1A receptors *in vivo* (iv admin). Unlike WAY100135, WAY100635 displays no partial agonist activity in the ventral hippocampus of rats.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Amylin (human), Endogenous peptide, 500UG
MW 3903.3 Da, Purity >95%. Amylin (human), Endogenous peptide. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam (R)-CPP (mM/ml), NMDA antagonist, 10MM_ML
MW 252.2 Da. Highly potent, competitive NMDA antagonist; more active enantiomer of (RS)-CPP (ab120160). (Ki values are 0.04, 0.3, 0.6 and 2.0 μM at NR1/NR2A, NR1/NR2B, NR1/NR2C and NR1/NR2D, respectively).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Prodigiosin, apoptotic agent, 250UG
MW 323.4 Da, Purity >95%. Potent apoptotic agent. Antibiotic agent. Induces caspase-dependent apoptosis. Inhibits mTORC1 and mTORC2. Reactivates p53. Inhibits iNOS expression. Shows anti-ischemic and antimalarial effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam (R)-CPP, NMDA antagonist, 50MG
MW 252.2 Da. Highly potent, competitive NMDA antagonist; more active enantiomer of (RS)-CPP (ab120160). (Ki values are 0.04, 0.3, 0.6 and 2.0 μM at NR1/NR2A, NR1/NR2B, NR1/NR2C and NR1/NR2D, respectively).
The product is subject to the following: Abcam Restricted Use Statement
Abcam UDP-glucose, Highly P2Y14 agonist, 500MG
MW 610.27 Da. Highly potent, endogenous P2Y14 agonist (EC50 = 82 nM). Involved in modulation of gastric function. UDP also available (ab120383).
The product is subject to the following: Abcam Restricted Use Statement
Abcam JC-1, Mitochondrial membrane potential dye, 5MG
MW 652.2 Da, Purity >95%. Mitochondrial membrane-potential dye. Exhibits potential-dependent accumulation in mitochondria. Fluorescence emission shift from green (~529 nm) to red (~590 nm). Depolarization is indicated by a decrease in the red/green fluorescence intensity ratio.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences meso-Tetraphenylporphyrin BioReagent, suitable for fluorescence, >=99.0% (HPLC) | 917-23-7 | MFCD00011680 | 250MG
meso-Tetraphenylporphyrin BioReagent, suitable for fluorescence, >=99.0% (HPLC) | Purity: >=99.0% (HPLC) | Mol Wt: 614.74 | 917-23-7 | MFCD00011680 | 250MG