Tetrapyrroles and derivatives
Abcam Rebo x etine mesylate, Noradrenaline reuptake inhibitor, 10MG
MW 409.5 Da, Purity >99%. Potent, selective noradrenaline reuptake inhibitor, with high selectivity over dopamine and 5-HT transporters. Antidepressant in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 5-Aza-2'-deo x ycytidine (Decitabine), DNMT1 inhibitor, 10MG
MW 228.21 Da, Purity >99%. Potent DNA methyltransferase 1 (DNMT1) inhibitor (IC₅₀ = 0.2 μM). Incorporated into DNA, inhibits DNMT1 activity to induce DNA hypomethylation. Interferes with protein synthesis. Shows antimetabolic and anticancer activities in vitro. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Cytochalasin D, actin polymerization inhibitor, 1MG
MW 507.6 Da, Purity >98%. Cytochalasin D, actin polymerization inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Necrostatin-1, necroptosis inhibitor, 10MG
MW 259.33 Da, Purity >99%. Potent, specific necroptosis inhibitor (EC₅₀ = 490 nM). Selective allosteric inhibitor of death domain receptor-associated adaptor kinase RIP1 in vitro (EC₅₀ = 182 nM). Caspase independent, programmed necrosis pathway.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 242084 hydrochloride, 5-HT2C antagonist, 50MG
MW 431.3 Da, Purity >98%. Potent, selective 5-HT2C antagonist (pKi values are 9 (5-HT2C), 7 (5-HT2B), 6.8 (5-HT2A), 6.4 (5-HT1A), 6.4 (5-HT1B), 6.4 (5-HT1D), 6 (5-HT1E), <6.1 (5-HT1F), <5.5 (5-HT4), 6 (5-HT6), 6.1 (5-HT7), 6.2 (D2), 6.2 (D3) and <5 (α1)). Blood-brain barrier permeable. Anxiolytic activity *in vivo*.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences Hemin BioXtra from Porcine5G
REAGENT Hemin BioXtra from Porcine5G
Sigma Aldrich Fine Chemicals Biosciences Bilirubin Oxidase from Myr
We are committed to bringing younbspGreenernbspAlternative Products which adhere to one or more of The 12 Principles ofnbspGreenernbspChemistry. This product has been enhanced for energy efficiency and waste prevention when used in biofuel cell research. for more information see the article in biofiles.Bilirubin oxidase (BOD) belongs to the sub class of multicopper oxidase family. It is usually found in fungi.
Abcam 3-Morpholinosydnonimine hydrochloride (SIN-1 hydrochloride), Vasodilator, 20MG
MW 206.63 Da, Purity >99%. Releases NO, superoxide and peroxynitrite under physiological conditions. Potent vasodilator and inhibitor of platelet aggregation. Active metabolite of molsidomine (ab142914). Protective in myocardial ischemia-reperfusion. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 206553 hydrochloride, 5-HT2B and 5-HT2C receptor antagonist, 50MG
MW 292.33 Da, Purity >99%. Potent and selective 5-HT2B and 5-HT2C serotonin receptor antagonist (pKi values are 7.92 (5-HT2C), 5.78 (5-HT2A), 7.65 (5-HT2B), 1A), 1D), 1E) and 1F). Centrally active following oral administration.
The product is subject to the following: Abcam Restricted Use Statement
Abcam EMD 386088 hydrochloride, 5-HT6 agonist, 50MG
MW 283.2 Da, Purity >98%. Potent 5-HT6 agonist (IC50 = 7.4 nM in 3H-LSD binding and EC50 = 1.0 nM in a functional cAMP assay). Selective over other 5-HT receptors (IC50 values are 110 (5-HT1D), 180 (5-HT1B), 240 (5-HT2A), 450 (5-HT2C), 620 (5-HT4), 660 (5-HT1A ) and 3000 nM (5-HT7)). Shows moderate affinity at 5-HT3 receptors (IC50 = 34 nM). Impairs memory *in vivo*.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB-3CT, MMP-2 and MMP-9 inhibitor, 5MG
MW 306.4 Da, Purity >98%. Potent, competitive and non-selective MMP-2 and MMP-9 inhibitor (Ki values are 13.9 and 600 nM for MMP-2 and MMP-9 respectively). Does not alter the activity of MMP-1, MMP-3 or MMP-7 (Ki values are 206 (MMP-1), 15 (MMP-3) and 96 (MMP-7) μM). Neuroprotective and blood-brain barrier permeable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 505124, ALK5 inhibitor, 1MG
MW 335.4 Da, Purity >98%. Potent, reversible, competitive ALK5 inhibitor (IC₅₀ values are 47 and 129 nM for ALK5 and ALK4 respectively). Inhibits ALK7 but not ALK1, 2, 3, or 6. Shows antifibrotic effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam P5091, USP-7 inhibitor, 5MG
MW 348.2 Da, Purity >98%. Potent, selective and cell-permeable USP-7 inhibitor (EC₅₀ = 4.2 μM). Induces apoptosis in cancer cells in vitro. Antiangiogenic and antitumor agent. Active in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 216641 hydrochloride, h5-HT1B antagonist, 50MG
MW 523.03 g/mol, Purity >98%. Selective h5-HT₁B receptor antagonist. 25-fold selectivity over h5-HT₁D. Little or no affinity for a range of other receptor subtypes.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Rhodadyn™ B10, Negative control for Rhodadyn™ C10, 5MG
MW 322.44 g/mol, Purity >98%. Negative control for Rhodadyn™ C10 (ab120795). Demonstrates no significant inhibition of dynamin I or dynamin II in vitro GTPase activity at concentrations up to 300 μM and has no effect on clathrin-mediated endocytosis of transferrin when applied for 30 minutes to U2OS cells in culture. Robertson J et al. The rhodadyn™ a new class of small molecule inhibitors of dynamin GTPase. ACS Med. Chem (2012).
The product is subject to the following: Abcam Restricted Use Statement