Carboximidamides
Chem-Impex International, Inc. 2-tert-Butyl-1,3-diisopropylisourea | 71432-55-8 | MFCD06657672 | 25G
2-tert-Butyl-1,3-diisopropylisourea, 71432-55-8, MFCD06657672, 25G
Chem-Impex International, Inc. Chloro-dipyrrolidinocarbenium hexafluorophosphate | MFCD00191333 | 25G
Chloro-dipyrrolidinocarbenium hexafluorophosphate, MFCD00191333, 25G
Medchemexpress LLC Melagatran | 159776-70-2 | 99.3% | 429.51 g·mol⁻¹ | C22H31N5O4 | 5 MG
Melagatran is a reversible, selective, orally active small-molecule direct inhibitor of thrombin for preclinical research. It binds the thrombin active site (Ki ≈ 2 nM), blocking thrombin-mediated conversion of fibrinogen to fibrin and modulating NF-κB and AP-1 pathways. Typical research applications include thrombosis, atherosclerosis, and ischemic brain injury models.
- Direct and potent thrombin inhibition with low nanomolar Ki.
- Suitable for in vitro and in vivo cardiovascular research.
- High reported purity (~99.3%) for reliable results.
- Solid powder form facilitating storage and handling.
- Storage recommendations: powder at -20°C; solutions at -80°C for long-term storage.
Medchemexpress LLC Allantoin (5-Ureidohydantoin) | 97-59-6 | 98.9% | 158.12 | 100 MG
Allantoin is a skin conditioning agent that promotes healthy skin and stimulates new and healthy tissue growth. It possesses anti-oxidative and anti-inflammatory activities and can ameliorate chemically-induced pancreatic β-cell damage.
- Promotes healthy skin and stimulates new tissue growth
- Exhibits anti-oxidative and anti-inflammatory activities
- Attenuates apoptosis and cytotoxicity, increasing β-cell viability
- Activates imidazoline 3 (I3) receptors
- Increases neuronal cell proliferation in the hippocampal dentate gyrus region
- Lowers plasma glucose and increases plasma insulin levels
- Decreases blood pressure
Medchemexpress LLC 1H-1,2,3-triazole-4-carboxamide derivative (BIIB091) | 2247614-80-6 | 99.9% | C28H34N10O2 | 10MG
BIIB091 is a potent, selective, reversible Bruton's tyrosine kinase (BTK) inhibitor supplied as a high-purity small-molecule reagent for research and preclinical studies. It is used to probe BTK signaling and to evaluate therapeutic approaches in autoimmune and B-cell-mediated disease models. Not for human or clinical use.
- Potent, selective reversible BTK inhibitor (IC50 <0.5 nM).
- High purity (99.85% by HPLC).
- Molecular formula C28H34N10O2; molecular weight 542.64.
- Suitable for in vitro and preclinical assays.
- Orally active profile reported in preclinical studies.
- Supplied as a powder; soluble in DMSO.
Medchemexpress LLC Melagatran | 159776-70-2 | 99.3% | 1 MG
Melagatran is a reversible, selective, and orally active direct inhibitor of thrombin, with a Ki of 2 nM. It functions by binding directly to the active site of thrombin, inhibiting the conversion of fibrinogen to fibrin. This compound also reduces the DNA binding activity of NF-κB and AP-1, making it relevant for research in cardiovascular diseases and ischemic brain damage. It has been shown to alleviate ischemic brain damage and decrease the size of advanced atherosclerotic lesions.
- Targets thrombin with a Ki of 2 nM.
- Alleviates endotoxin-induced systemic hemodynamic disorders.
- Prevents or delays electrically induced occlusive thrombus formation.
- Demonstrates good oral bioavailability.
- Reduces ischemic brain injury in rats.
- Reduces advanced atherosclerotic lesion size and promotes plaque stability.
- Decreases DNA binding activity of NF-κB and AP-1.
Medchemexpress LLC H3B-6545 | 2052130-80-8 | 99.4% | 567.58 | 50 MG
H3B-6545 is an oral, selective estrogen receptor covalent antagonist (SERCA) for the research of metastatic ER-positive, HER2-negative breast cancer. It is for research use only and not sold to patients.
- Oral, selective estrogen receptor covalent antagonist (SERCA).
- Designed for research into metastatic ER-positive, HER2-negative breast cancer.
- Potently antagonizes wild-type and mutant ERα in biochemical and cell-based assays.
- Inactivates wild-type and mutant ERα by targeting C530.
- Inhibits ERαWT activity and suppresses proliferation of ERαWT-positive breast cancer cell lines.
- Demonstrates superior efficacy to fulvestrant and tamoxifen in xenograft and patient-derived xenograft models.
- Well tolerated across a broad dose range in rats and monkeys.
(F)(F)(F)F.FC(N1CCCC1)=[N+]1CCCC1 | 5g | 536854647](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC2038846.JPG-250.jpg)
eMolecules 1-(Fluoro(pyrrolidin-1-yl)methylene)pyrrolidin-1-ium hexafluorophosphate(V)(BTFFH) | ChemScene | 164298-25-3 | MFCD02683430 | 316.204 | C9H16F7N2P | 98.000 | F[P-](F)(F)(F)(F)F.FC(N1CCCC1)=[N+]1CCCC1 | 5g | 536854647
1-(Fluoro(pyrrolidin-1-yl)methylene)pyrrolidin-1-ium hexafluorophosphate(V)(BTFFH) | ChemScene | 164298-25-3 | MFCD02683430 | 316.204 | C9H16F7N2P | 98.000 | F[P-](F)(F)(F)(F)F.FC(N1CCCC1)=[N+]1CCCC1 | 5g | 536854647
Chem-Impex International, Inc. 2-tert-Butyl-1,3-diisopropylisourea | 71432-55-8 | MFCD06657672 | 5G
2-tert-Butyl-1,3-diisopropylisourea, 71432-55-8, MFCD06657672, 5G
STA PHARMACEUTICAL US LLC ANA 2'-F U amidite | 1 g | CAS 1190089-70-3 | MDL MFCD15145421
ANA 2'-F U amidite is a Amidite reagent (Subcategory: ANA Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 1190089-70-3
- MDL: MFCD15145421
- InChIKey: HQHQPAYRJJMYQX-CPBIVIIKSA-N
- Molecular Weight: 748.789165161
- Molecular Formula: C39H46FN4O8P
- Purity: ≥98%
- Container Type: 30 mL Glass (28-400)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 50.1 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(NC(C=C5)=O)=O)F)OCCC#N)C(C)C)C
![eMolecules Ambeed / 55-(14-Phenylene)dipicolinaldehyde / 100mg / 603089926 / A1226399 / / 1399191-70-8 / [null] / 288.306 / C18H12N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502461975.JPG-250.jpg)
eMolecules Ambeed / 55-(14-Phenylene)dipicolinaldehyde / 100mg / 603089926 / A1226399 / / 1399191-70-8 / [null] / 288.306 / C18H12N2O2
Ambeed / 55-(14-Phenylene)dipicolinaldehyde / 100mg / 603089926 / A1226399 / / 1399191-70-8 / [null] / 288.306 / C18H12N2O2
Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | 99.8% | 327.89 | C21H26ClN | 10 MG
Melitracen hydrochloride is a tricyclic antidepressant research compound supplied as the hydrochloride salt and used as a chemically characterized reference for laboratory studies. It inhibits norepinephrine and serotonin uptake and is provided in small, labeled packs for analytical and formulation work.
- High chemical purity (reported ~99.8%) for analytical applications.
- Hydrochloride salt form for consistent physicochemical properties.
- Molecular weight 327.89 and molecular formula C21H26ClN.
- Available in multiple small pack sizes suitable for research and testing.
- Supplied with product documentation and batch information.
Medchemexpress LLC VAS 3947 | 869853-70-3 | 99.59% | 310.33 | 5 G
VAS 3947 | 869853-70-3 | 99.59% | 310.33 | 5 G
Medchemexpress LLC Creatine kinase M-type (CKM) protein, human (N-His tag) | 9001-15-4 | >95.0% | 10 UG
Recombinant human creatine kinase M-type (CKM) protein with an N-terminal His tag, expressed in E. coli and supplied as a purified, biologically active enzyme for research use. The protein is approximately 45 kDa, available in microgram quantities, and characterized for activity and purity (>95% by reducing SDS-PAGE). Intended for biochemical assays, enzyme activity studies, and antibody validation; not for clinical or diagnostic use.
- Recombinant human CKM with N-terminal His tag.
- Expressed in E. coli for high-yield production.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Biologically active and suitable for enzymatic assays.
- Supplied in microgram quantities for small-scale experiments.
- Datasheet and COA provided for lot-specific quality information.