Carboximidamides
Medchemexpress LLC Clonidine hydrochloride | 4205-91-8 | 99.9% | 1 ML
Clonidine hydrochloride is an agonist of α2-adrenoceptor and a potent antihypertensive agent, primarily intended for research use. This specific product is a 10 mM solution in DMSO.
- Agonist of α2-adrenoceptor
- Potent antihypertensive agent
- For research use only
- High purity: 99.9%
- Induces CGRP mRNA expression in endothelial cells
- Increases NO level in endothelial cells
- Suppresses dopamine efflux in the prefrontal cortex
- Solution stable at -20°C for 1 month or -80°C for 6 months
eMolecules 2978-11-2 | 4-Nitrobenzyl N,N'-diisopropylcarbamimidate | MFCD00042046 | 1g
Medchem Express | BGC-20-1531 (free base) | 5mg | 649421726 | HY-19849 | 736183-35-0 | 492.550 | C26H24N2O6S
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Medchemexpress LLC Isosinensetin | 17290-70-9 | MFCD21333406 | 99.9% | 372.37 | C20H20O7 | 10 MG
Isosinensetin is a naturally occurring flavonoid research compound used as an inhibitor of HIV-1 protease and protein tyrosine phosphatase 1B (PTP1B), with reported activity against P-glycoprotein. It is provided as a high-purity reagent for biochemical and cell-based studies.
- High purity (99.9%) suitable for research applications.
- Molecular formula C20H20O7; molecular weight 372.37.
- Reported biological activities include PTP1B and HIV-1 protease inhibition and P-gp modulation.
- Recommended storage: 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month).
- Supplied as a 10 mg vial for small-scale laboratory research.
Medchemexpress LLC Pentagamavunon-1 | 27060-70-4 | MFCD07958657 | 99.0% | C23H24O3 | 10MG
Pentagamavunon-1 (PGV-1) is a synthetic curcumin analog used in preclinical research as a cyclooxygenase (COX) inhibitor and apoptosis-inducing agent. It is employed in cellular and in vivo studies to investigate tumor suppression, reactive oxygen species (ROS) metabolism, and cell-cycle effects, and is provided as a stable solid with guidance for solvent preparation and storage.
- Curcumin analog with reported oral activity.
- Inhibits COX and modulates ROS metabolic enzymes.
- Induces apoptosis and M-phase (prometaphase) cell-cycle arrest.
- High purity suitable for research use (~99%).
- Soluble in DMSO for in vitro stock preparation.
- Stable with recommended low-temperature storage for long-term preservation.
Medchemexpress LLC Glycyrrhisoflavone | 116709-70-7 | 99.4% | 354.35 g·mol⁻¹ | C20H18O6 | 10 MG
Glycyrrhisoflavone is an active prenylflavonoid that inhibits α-glucosidase, provided as an analytical standard for research and analytical applications. It is supplied with defined purity and molecular characterization useful for assay development and analytical workflows.
- High purity of 99.43%.
- Provided as a 10 mg analytical standard.
- Useful as an α-glucosidase inhibitor in biochemical assays.
- Well-characterized molecular properties: C20H18O6, molecular weight 354.35 g·mol⁻¹.
- CAS number 116709-70-7 for unambiguous identification.
- For research use only; not for human or clinical use.
Selleck Chemical LLC Methylguanidine HCl
Methylguanidine is a guanidine compound deriving from protein catabolism
Chem-Impex International, Inc. N,N'-Dicyclohexyl-4-morpholinecarboxamidine | MFCD00063252 | 5G
N,N'-Dicyclohexyl-4-morpholinecarboxamidine, MFCD00063252, 5G
eMolecules 82504-70-9 | Ambeed | N2N4N6-tri-m-tolyl-135-Triazine-246-triamine | 250mg | 586454501 | A310637 | MFCD19440763 | 396.498 | C24H24N6
Ambeed | N2N4N6-tri-m-tolyl-135-Triazine-246-triamine | 250mg | 586454501 | A310637 | 82504-70-9 | MFCD19440763 | 396.498 | C24H24N6
Selleck Chemical LLC Clonidine HCl S2458-50mg
Clonidine HCl(Kapvay) is a direct-acting 2 adrenergic agonist with an ED50 of 0 02 0 01 mg/kg
Medchemexpress LLC Benzamidine hydrochloride | 1670-14-0 | 156.61 g/mol |
Benzamidine hydrochloride | 1670-14-0 | 156.61 g/mol |
eMolecules 1187927-61-2 | N-(4-Chloro-phenyl)-guanidine oxalate | J & W PharmLab LLC | MFCD11506084 | 259.650 | C9H10ClN3O4 | 96.000 | OC(=O)C(O)=O.NC(=N)Nc1ccc(Cl)cc1 | 500mg | 553408292
N-(4-Chloro-phenyl)-guanidine oxalate | J & W PharmLab LLC | 1187927-61-2 | MFCD11506084 | 259.650 | C9H10ClN3O4 | 96.000 | OC(=O)C(O)=O.NC(=N)Nc1ccc(Cl)cc1 | 500mg | 553408292
eMolecules 50-01-1 | Guanidine hydrochloride | Chem-Impex | MFCD00013026 | 95.530 | CH6ClN3 | 99.000 | Cl.NC(N)=N | 10kg | 342450114
Guanidine hydrochloride | Chem-Impex | 50-01-1 | MFCD00013026 | 95.530 | CH6ClN3 | 99.000 | Cl.NC(N)=N | 10kg | 342450114
Medchemexpress LLC BX430 | 688309-70-8 | 99.2% | 413.11 | 1 ML
BX430 is a potent and selective noncompetitive allosteric human P2X4 receptor channels antagonist with an IC50 of 0.54 μM. It exhibits species specificity and is used for chronic pain and cardiovascular disease.
- Has virtually no functional impact on all other P2X subtypes (P2X1-P2X3, P2X5, and P2X7).
- Potent antagonist of zebrafish P2X4.
- Reduces intracellular calcium rise evoked by ATP in human P2X4-expressing cells.
- Markedly reduces the amplitude of ATP-evoked intracellular calcium responses in THP-1 cells.
Medchemexpress LLC Guanidine-d5 hydrochloride | 108694-93-5 | MFCClD6N3 | 98% | 25 MG
Guanidine-d5 (hydrochloride) is the deuterium labeled Guanidine hydrochloride. Guanidine hydrochloride (Guanidinium chloride) is a strong chaotrope and also a strong denaturant of proteins.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules largely as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Yuanhuacine (Gnidilatidin) | 60195-70-2 | 1 MG
Yuanhuacine (Gnidilatidin), a diterpene from *Daphne genkwa*, is an effective and highly selective inhibitor of the basal-like 2 (BL2) subtype of TNBC. It can induce G2/M cell cycle arrest and exhibits broad anti-tumor activity. Yuanhuacine is an orally active DNA damaging agent.
- Highly selective inhibitor for the BL2 subtype of TNBC.
- Induces G2/M cell cycle arrest.
- Exhibits broad anti-tumor activity.
- Acts as an orally active DNA damaging agent.
- Inhibits proliferation in various cancer cell lines including H1993, H358, H460, Calu-1, H1299, A549, UMUC3, and HCT116.
- Downregulates mTOR activation.
- Inhibits migration of H1993 cells.
- Upregulates p21 transcription and protein expression by regulating Sp1 protein stability.