Carboximidamides
Medchemexpress LLC Guanidine, N-methyl-, hydrochloride (1:1) | 21770-81-0 | 109.56 | 500 MG
1-Methylguanidine monohydrochloride is provided as a white to off-white solid. It has been tested and complies with the given specifications. This product is intended for research use only and has not been fully validated for medical applications.
- White to off-white solid appearance
- Tested and complies with specifications
- Storage at 4°C, sealed, away from moisture
- In solvent, store at -80°C for 6 months or -20°C for 1 month, sealed and away from moisture
Medchemexpress LLC Creatine (Standard) | 57-00-1 | 99.98% | 131.13 | 50 MG
Creatine (Standard) is an analytical standard of Creatine, an endogenous amino acid derivative crucial for cellular energy in muscle and brain. It is designed for research and analytical applications, serving as a reference in various assays.
- Used in qualitative research experiments.
- Used in quantitative research experiments.
- Used in methodological research experiments.
- Applicable in HPLC.
- Applicable in GC.
- Applicable in MS.
Medchemexpress LLC Fluorizoline 50mg | 1362243-70-6 | 362.20 g/mol | C15H8Cl2F3NS | 50 MG
Fluorizoline is a small-molecule antitumor agent that selectively binds prohibitin 1 (PHB1) and prohibitin 2 (PHB2) to induce apoptosis. It reduces chronic lymphocytic leukemia (CLL) cell viability through upregulation of NOXA and BIM and demonstrates activity independent of p53. The compound is supplied as a solid powder for preclinical research.
- High purity (99.77%) suitable for research assays.
- Molecular weight 362.20 g/mol and formula C15H8Cl2F3NS.
- Soluble in DMSO (50 mg/mL); may require ultrasonic treatment.
- Powder stable at -20°C for long-term storage.
- Direct binder of prohibitin proteins; useful for apoptosis and mechanism-of-action studies.
Medchemexpress LLC 11R-VIVIT (cell permeable NFAT inhibitor) | 592517-80-1 | 99.6% | 3573.15 | 5 MG
11R-VIVIT is a cell-permeable nuclear factor of activated T cells (NFAT) inhibitor. It is suitable for the research of podocyte and diabetic nephropathy.
- Significantly reduces NFAT2 expression in high glucose-treated podocytes
- Attenuates high glucose-induced filtration barrier dysfunction of podocytes
- Abrogates increased urinary albumin excretion rates
- Attenuates glomerular basement membrane (GBM) thickening and podocyte foot process effacement
- Partially restores podocyte number
- Inhibits NFAT2 activation and uPAR expression in glomerular podocytes
Medchemexpress LLC Meloside A (Isovitexin 2''-O-glucoside) | 60767-80-8 | 5 MG
Meloside A, also known as Isovitexin 2''-O-glucoside, is a phenylpropanoid found in barley known for its antioxidant activity. This compound can inhibit cell apoptosis and reduce reactive oxygen species (ROS) production. It also demonstrates an ability to inhibit androgen receptor (AR) nuclear translocation and AR protein expression. Furthermore, Meloside A can decrease the levels of IL-6, TGF-β1, and DKK-1, making it a valuable tool for research in inflammation and endocrinology, including studies related to hair loss.
- Exhibits antioxidant activity
- Inhibits cell apoptosis and ROS production
- Inhibits androgen receptor (AR) nuclear translocation and expression
- Reduces IL-6, TGF-β1, and DKK-1 levels
- Useful for inflammation and endocrinology research
- Does not induce significant cytotoxicity in HDPCs (5-100 μg/mL, 24 h)
STA PHARMACEUTICAL US LLC ANA 2'-F U amidite | 5 g | CAS 1190089-70-3 | MDL MFCD15145421
ANA 2'-F U amidite is a Amidite reagent (Subcategory: ANA Series) sold by WuXi TIDES. Offered in 5 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 1190089-70-3
- MDL: MFCD15145421
- InChIKey: HQHQPAYRJJMYQX-CPBIVIIKSA-N
- Molecular Weight: 748.789165161
- Molecular Formula: C39H46FN4O8P
- Purity: ≥98%
- Container Type: 250 mL Glass (28-400)
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 174.7 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(NC(C=C5)=O)=O)F)OCCC#N)C(C)C)C
Medchemexpress LLC Creatine | 57-00-1 | 100.0% | 131.13 | 1 ML
Creatine is an endogenous amino acid derivative that plays a crucial role in cellular energy, particularly in muscle and brain function. It is involved in energy storage and transfer, supporting high-intensity, short-duration activities. This product is supplied as a 10 mM solution in 1 mL of water, prepared for reconstitution.
- Endogenous metabolite
- Involved in cellular energy production
- Supports muscle and brain function
- Supplied as a ready-for-reconstitution solution
Medchemexpress LLC Isosinensetin | 17290-70-9 | 372.37 | 20 MG
Isosinensetin is a flavonoid compound and an inhibitor of HIV-1 protease and PTP1B (IC50: 2.61 μM; Ki: 0.92 μM). It inhibits P-glycoprotein (P-gp) in MDR1-MDCKII cells. Isosinensetin possesses anti-tumor, anti-viral, anti-inflammatory, and antioxidant effects. It is used in research for various diseases including cancer, inflammation, osteoporosis, and diabetes.
- Inhibits HIV-1 protease and PTP1B
- Inhibits P-glycoprotein
- Possesses anti-tumor, anti-viral, anti-inflammatory, and antioxidant effects
- Used in research for cancer, inflammation, osteoporosis, and diabetes
- Inhibits osteoclast formation and bone resorption
- Alleviates estrogen deficiency-induced osteoporosis
- Increases intracellular calcium ion concentration
- Stimulates GLP-1 secretion
- Inhibits erythrocyte hemolysis
Medchemexpress LLC 1-Methylguanidine monohydrochloride | 21770-81-0 | 109.56 | 1 G
1-Methylguanidine monohydrochloride is an endogenous metabolite. It is for research use only and not sold to patients.
- Endogenous metabolite
- White to off-white solid appearance
- High purity of 98.0%
- Molecular weight: 109.56
- Solid storage: 4°C, sealed, away from moisture
- In solvent storage: -80°C for 6 months; -20°C for 1 month (sealed, away from moisture)
Medchemexpress LLC Steviol analytical standard | 471-80-7 | MFCD00210558 | >98.0% | 318.45 | C20H30O3 | 10 MG
Steviol is an analytical reference standard of the diterpene steviol, the primary metabolite of steviol glycosides, supplied for research and analytical applications. It is reported to inhibit AQP2 and CFTR and is provided in small laboratory pack sizes suitable for analytical work.
- Intended as an analytical reference standard for research and analysis.
- Primary metabolite of steviol glycosides.
- Reported inhibitor of AQP2 and CFTR (per supplier literature).
- Available in small laboratory pack sizes, including 10 mg.
- CAS number 471-80-7 and molecular formula C20H30O3.
- Supplied for use in analytical assays and method development.
eMolecules 321-70-0 | 6-(TRIFLUOROMETHYL)QUINOLIN-8-OL | AstaTech | MFCD18417211 | 213.159 | C10H6F3NO | 95.000 | Oc1cc(cc2cccnc12)C(F)(F)F | 0.1g | 798867065
6-(TRIFLUOROMETHYL)QUINOLIN-8-OL | AstaTech | 321-70-0 | MFCD18417211 | 213.159 | C10H6F3NO | 95.000 | Oc1cc(cc2cccnc12)C(F)(F)F | 0.1g | 798867065
![eMolecules 1260850-70-1 | Ambeed | 3-Bromoimidazo[12-b]pyridazin-6-ylamine | 250mg | 490506710 | A134690 | MFCD11520885 | 213.038 | C6H5BrN4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502448762.PNG-250.jpg)
eMolecules 1260850-70-1 | Ambeed | 3-Bromoimidazo[12-b]pyridazin-6-ylamine | 250mg | 490506710 | A134690 | MFCD11520885 | 213.038 | C6H5BrN4
Ambeed | 3-Cyano-3-phenylpropanoic acid | 250mg | 600839234 | A390691 | 14387-18-9 | MFCD03032627 | 175.187 | C10H9NO2
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eMolecules 64513-70-8 | 2-(CYCLOPROPANECARBOXAMIDO)ACETIC ACID | AstaTech | MFCD01724840 | 143.142 | C6H9NO3 | 95.000 | OC(=O)CNC(=O)C1CC1 | 0.25g | 384830441
2-(CYCLOPROPANECARBOXAMIDO)ACETIC ACID | AstaTech | 64513-70-8 | MFCD01724840 | 143.142 | C6H9NO3 | 95.000 | OC(=O)CNC(=O)C1CC1 | 0.25g | 384830441
Alkali Scientific Guanidine Hydrochloride, 500 G
Guanidine Hydrochloride, available in a 500g format, is a powerful chaotropic agent used extensively in molecular biology for protein denaturation and nucleic acid isolation. It disrupts protein structures by breaking hydrogen bonds and other stabilizing interactions, making it ideal for extracting nucleic acids or for use in protein unfolding studies. This reagent is commonly used in protocols for RNA, DNA, and protein purification, especially in the preparation of samples for further biochemical analysis. Its versatility extends to use in protein-protein interaction studies and structural analysis of biomolecules in research labs.
Medchemexpress LLC Creatine Kinase (CPK/CK), Bovine Heart | 9001-15-4 | 1 KU
Creatine Kinase (CPK/CK), Bovine Heart is a biological material or organic compound that can be used in life science research. It is for research use only and not sold to patients.
- Biological material
- Organic compound
- Used in life science research