Carboximidamides
Apexbio Technology LLC Guanidine HCl 50-01-1 50g
Guanidine hydrochloride (Guanidine HCl CAS 50-01-1) is a highly alkaline crystalline compound derived from the oxidative metabolism of guanine Functioning primarily as a strong chaotropic agent it disrupts hydrogen bonding and secondary structure in proteins leading to efficient protein denaturation and solubilization Widely utilized in molecular biology and biochemistry Guanidine HCl facilitates protein unfolding for downstream applications such as protein purification refolding studies and RNA extraction protocols where it also serves to inactivate nucleases and other enzymes
Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | 99.8% | 327.89 | C21H26ClN | 100 MG
Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | 99.8% | 327.89 | C21H26ClN | 100 MG
Medchemexpress LLC Creatine kinase MB (rCK-MB), recombinant human (CK-MB) | 9001-15-4 | 100 UG
Creatine Kinase MB (rCK-MB), Recombinant Human (CK-MB) is a biological material or organic compound that can be used in life science research. This product is intended for research use only.
- Appearance: liquid, colorless to light yellow.
- Enzyme activity: > 400 U/mL.
- Unit definition: one unit is defined as the amount of enzyme that catalyzes the transphosphorylation of one micromole of phosphate from creatine phosphate to ADP per minute at 37°C.
- Shipping with dry ice.
- Store under recommended conditions in the certificate of analysis.
eMolecules 62119-70-4 | 2-(Benzofuran-2-yl)acetic acid | ChemScene | MFCD00052742 | 176.171 | C10H8O3 | 97.000 | OC(=O)Cc1cc2ccccc2o1 | 100mg | 632281354
2-(Benzofuran-2-yl)acetic acid | ChemScene | 62119-70-4 | MFCD00052742 | 176.171 | C10H8O3 | 97.000 | OC(=O)Cc1cc2ccccc2o1 | 100mg | 632281354
Medchemexpress LLC Triphenylphosphonium-derivatized anethole dithiolethione | 1429061-80-2 | 96.4% | 721.77 g/mol | C37H38BrO2PS3 | 10MG
AP39 is a mitochondria-targeted hydrogen sulfide (H2S) donor, a triphenylphosphonium-derivatized anethole dithiolethione used in preclinical research to raise mitochondrial H2S levels and protect against oxidative damage. It has demonstrated cytoprotective activity and preservation of mitochondrial DNA in cellular and animal models of ischemia and neurodegeneration.
- Mitochondria-targeted delivery via a lipophilic cationic moiety.
- Releases hydrogen sulfide (H2S) within mitochondria.
- Exhibits cytoprotective effects under oxidative stress.
- Preserves mitochondrial DNA integrity in preclinical studies.
- Recommended storage and handling per supplier documentation.
Medchemexpress LLC BIIB091 | 2247614-80-6 | 99.9% | 542.64 | 50 MG
BIIB091 is a potent, selective, orally active, and reversible BTK inhibitor, with an IC50 of <0.5 nM. It binds the BTK protein to sequester TYR-551 into an inactive conformation with excellent affinity. BIIB091 can be used for the research of multiple sclerosis.
- Potent and selective BTK inhibitor
- Orally active and reversible
- Excellent affinity
- Used for multiple sclerosis research
Medchemexpress LLC Nardosinone | 23720-80-1 | 250.33 | 5 MG
Nardosinone, isolated from Nardostachys chinensis, is identified as the first enhancer of the neuritogenic action of dbcAMP and staurosporine. It may serve as a pharmacological tool for studying the mechanism of action of nerve growth factor (NGF) and other neuritogenic substances.
- Purity of 99.81%
- Appearance as a white to off-white solid
- Store at 4°C, protected from light; in solvent, store at -80°C for 6 months or -20°C for 1 month
- Soluble in DMSO at 100 mg/mL
- Initial source from plants, Valerianaceae, Nardostachys jatamansi (D. Don) DC.
- Classified as a terpenoid, sesquiterpene
- Exhibits antiinflammatory activity in RAW264.7 cells with an IC50 of 11.1 μM
eMolecules 400748-70-1 | AstaTech | 3-(3-METHOXYPHENYL)ANILINE | 1g | 411873561 | AC1793 | 97 | MFCD03424667 | 199.253 | C13H13NO
ChemScene | 2-Chloro-4-methoxynicotinaldehyde | 100mg | 572184891 | CS-0082154 | 905563-79-3 | MFCD15474989 | 171.580 | C7H6ClNO2
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Medchemexpress LLC PIN1 inhibitor API-1 50mg | 680622-70-2 | 366.30 | C15H13F3N6O2 | 50 MG
PIN1 inhibitor API-1 is a selective peptidyl-prolyl cis-trans isomerase Pin1 inhibitor (IC50 = 72.3 nM) that binds the Pin1 PPIase domain and has been reported to up-regulate anticancer microRNA biogenesis and suppress hepatocellular carcinoma in preclinical models.
- Selective Pin1 inhibitor (IC50 72.3 nM).
- Molecular formula C15H13F3N6O2; molecular weight 366.30.
- Purity 99.63%.
- Appearance solid; color white to yellow.
- Soluble in DMSO (250 mg/mL); in vivo formulations ≥ 2.17 mg/mL in mixed solvents.
- Available in multiple package sizes including 50 MG.
Medchemexpress LLC PXS-5120A | 2125955-70-4 | 98.1% | 100 MG
PXS-5120A is a potent, irreversible fluoroallylamine inhibitor of Lysyl Oxidase-like 2/3 (LOXL2/3) with anti-fibrotic activity. It exhibits high selectivity for LOXL2 over LOXL and effectively inhibits various forms of LOXL2 and LOXL3. In vivo studies demonstrate its rapid absorption and hydrolysis to the active free base, maintaining therapeutic plasma concentrations for extended periods.
- Potent, irreversible fluoroallylamine inhibitor of LOXL2/3
- Exhibits anti-fibrotic activity
- Over 300-fold selective for LOXL2 over LOXL
- Effectively inhibits recombinant human LOXL2, human fibroblast LOXL2, recombinant mouse LOXL2, recombinant rat LOXL2, and collagen oxidation assay
- Inhibits recombinant human LOXL3 and recombinant human LOXL4
- Readily absorbed orally and rapidly hydrolyzed to the active free base
- Maintains plasma concentrations above LOXL2 IC50 for prolonged periods in mice
STA PHARMACEUTICAL US LLC ANA 2'-F U amidite | 1 g | CAS 1190089-70-3 | MDL MFCD15145421
ANA 2'-F U amidite is a Amidite reagent (Subcategory: ANA Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 1190089-70-3
- MDL: MFCD15145421
- InChIKey: HQHQPAYRJJMYQX-CPBIVIIKSA-N
- Molecular Weight: 748.789165161
- Molecular Formula: C39H46FN4O8P
- Purity: ≥98%
- Container Type: 15 mL HDPE
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 7.8 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(NC(C=C5)=O)=O)F)OCCC#N)C(C)C)C
STA PHARMACEUTICAL US LLC ANA 2'-F U amidite | 5 g | CAS 1190089-70-3 | MDL MFCD15145421
ANA 2'-F U amidite is a Amidite reagent (Subcategory: ANA Series) sold by WuXi TIDES. Offered in 5 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 1190089-70-3
- MDL: MFCD15145421
- InChIKey: HQHQPAYRJJMYQX-CPBIVIIKSA-N
- Molecular Weight: 748.789165161
- Molecular Formula: C39H46FN4O8P
- Purity: ≥98%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(NC(C=C5)=O)=O)F)OCCC#N)C(C)C)C
Medchemexpress LLC Dryocrassin ABBA | 12777-70-7 | 820.83 | 5 MG
Dryocrassin ABBA (Dryocrassin) is an orally active phloroglucinol derivative extracted from *Phyllopteris officinalis*. It demonstrates antitumor and antiviral activity, and induces apoptosis of human hepatocellular carcinoma cells via a mitochondrial pathway mediated by Caspase.
- Possesses antitumor activity
- Exhibits antiviral activity
- Induces apoptosis in human hepatocellular carcinoma cells via a mitochondrial pathway
- Inhibits S. aureus SrtA (sortase A) activity