Carboximidamides
![Medchemexpress LLC 7-ethyl-4-[3-(4-ethylsulfonyl-2-methoxyphenyl)-4-fluorophenyl]imidazo[4,5-c]pyridazine | 1614245-70-3 | 99.3% | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000230822.png-250.jpg)
Medchemexpress LLC 7-ethyl-4-[3-(4-ethylsulfonyl-2-methoxyphenyl)-4-fluorophenyl]imidazo[4,5-c]pyridazine | 1614245-70-3 | 99.3% | 100 MG
Darigabat is an orally active, subtype-selective GABAA positive allosteric modulator (PAM) used in preclinical and research studies to investigate GABAA receptor pharmacology, anxiolytic effects, and anticonvulsant potential.
- Subtype-selective GABAA PAM targeting α2/α3/α5 subunits.
- High purity (99.3%) suitable for research applications.
- Blood-brain barrier penetrant with demonstrated anxiolytic activity in models.
- Available as solid or DMSO solution; multiple package sizes offered.
- Useful for pharmacology, pain, anxiety, and epilepsy research.
Medchemexpress LLC Creatine kinase M-type/CKM protein, mouse (His) | >90.0% | 50UG
Recombinant mouse creatine kinase M-type (CKM) is supplied as a lyophilized, His-tagged protein expressed in E. coli for research use. CKM catalyzes reversible phosphate transfer between ATP and creatine phosphate and supports energy buffering in high-demand tissues. The material is provided with high purity and low endotoxin and is intended for biochemical assays, enzymology, and antibody validation. Store frozen and follow supplier reconstitution recommendations.
- High purity (>90%) as determined by reducing SDS-PAGE.
- Lyophilized formulation for long-term storage and convenient reconstitution.
- Expressed in E. coli with an N-terminal 6xHis tag to facilitate purification.
- Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
- Molecular weight approximately 49.0 kDa, consistent with the CKM isoform.
- Recommended storage at -20°C; stable short term at 4°C after reconstitution.
Medchemexpress LLC PIN1 inhibitor API-1 50mg | 680622-70-2 | 366.30 | C15H13F3N6O2 | 50 MG
PIN1 inhibitor API-1 is a selective peptidyl-prolyl cis-trans isomerase Pin1 inhibitor (IC50 = 72.3 nM) that binds the Pin1 PPIase domain and has been reported to up-regulate anticancer microRNA biogenesis and suppress hepatocellular carcinoma in preclinical models.
- Selective Pin1 inhibitor (IC50 72.3 nM).
- Molecular formula C15H13F3N6O2; molecular weight 366.30.
- Purity 99.63%.
- Appearance solid; color white to yellow.
- Soluble in DMSO (250 mg/mL); in vivo formulations ≥ 2.17 mg/mL in mixed solvents.
- Available in multiple package sizes including 50 MG.
![eMolecules ChemScene / 3-((Difluoromethyl)sulfonyl)propan-1-amine hydrochloride / 100mg / 718356374 / CS-0531488 / 0.000 / 2490400-70-7 / [null] / 209.640 / C4H10ClF2NO2S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502479541.JPG-250.jpg)
eMolecules ChemScene / 3-((Difluoromethyl)sulfonyl)propan-1-amine hydrochloride / 100mg / 718356374 / CS-0531488 / 0.000 / 2490400-70-7 / [null] / 209.640 / C4H10ClF2NO2S
ChemScene / 3-((Difluoromethyl)sulfonyl)propan-1-amine hydrochloride / 100mg / 718356374 / CS-0531488 / 0.000 / 2490400-70-7 / [null] / 209.640 / C4H10ClF2NO2S
Selleck Chemical LLC Clonidine HCl S2458-50mg
Clonidine HCl(Kapvay) is a direct-acting 2 adrenergic agonist with an ED50 of 0 02 0 01 mg/kg
eMolecules AstaTech / 6-(TRIFLUOROMETHYL)QUINOLIN-8-OL / 0.1g / 798867065 / 76328 / 95.000 / 321-70-0 / MFCD18417211 / 213.159 / C10H6F3NO
AstaTech / 6-(TRIFLUOROMETHYL)QUINOLIN-8-OL / 0.1g / 798867065 / 76328 / 95.000 / 321-70-0 / MFCD18417211 / 213.159 / C10H6F3NO
eMolecules Chem-Impex Guanidine hydrochloride 10kg 342450118 29914 0 000 50-01-1 MFCD00013026 95 530 CH6ClN3
Chem-Impex Guanidine hydrochloride 10kg 342450118 29914 0 000 50-01-1 MFCD00013026 95 530 CH6ClN3
eMolecules ChemScene / 2-(Benzofuran-2-yl)acetic acid / 100mg / 632281354 / CS-0138270 / 0.000 / 62119-70-4 / MFCD00052742 / 176.171 / C10H8O3
ChemScene / 2-(Benzofuran-2-yl)acetic acid / 100mg / 632281354 / CS-0138270 / 0.000 / 62119-70-4 / MFCD00052742 / 176.171 / C10H8O3
Medchemexpress LLC ((bis(3-chloro-4-methylphenyl)boraneyl)oxy)(3-hydroxypyridin-2-yl)methanone | 872044-70-7 | MFCD18251581 | 99.0% | 400.06 g/mol | C20H16BCl2NO3 | 5 MG
AN0128 is a boron-containing antibacterial and anti-inflammatory research compound with demonstrated in vitro activity against several Gram-positive bacteria. It is intended for use in preclinical research on periodontal and cutaneous diseases and is supplied as a solid with high purity; handle protected from light.
Medchemexpress LLC GDC-0276 50mg | 1494581-70-2 | 50 MG
Selective, orally active NaV1.7 inhibitor research compound intended for preclinical and clinical pharmacology studies. Demonstrates sub-nanomolar potency and favorable pharmacokinetics; supplied as a high-purity small-molecule solid for laboratory use.
- High purity (99.7%).
- Molecular weight 462.58.
- Chemical formula C24H31FN2O4S.
- Reported potency IC50 = 0.4 nM (NaV1.7).
- Supplied quantity 50 MG.
![eMolecules 131106-70-2 | Ambeed | 6-(Trifluoromethyl)benzo[d]thiazole | 100mg | 518525230 | A365025 | MFCD06659653 | 203.18 | C8H4F3NS](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502455386.PNG-250.jpg)
eMolecules 131106-70-2 | Ambeed | 6-(Trifluoromethyl)benzo[d]thiazole | 100mg | 518525230 | A365025 | MFCD06659653 | 203.18 | C8H4F3NS
Medchem Express | Berberrubine (chloride) | 5mg | 533802409 | HY-125850 | 15401-69-1 | MFCD01658905 | 357.790 | C19H16ClNO4
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eMolecules Pharmablock / (2E)-3-cyclobutylprop-2-enoic acid / 25mg / 551154888 / PBTQ8178 / 0.000 / 1355450-70-2 / MFCD06227778 / 126.155 / C7H10O2
Pharmablock / (2E)-3-cyclobutylprop-2-enoic acid / 25mg / 551154888 / PBTQ8178 / 0.000 / 1355450-70-2 / MFCD06227778 / 126.155 / C7H10O2
Medchemexpress LLC Creatine kinase, bovine heart | 9001-15-4 | 5 KU
Creatine Kinase (CPK/CK), Bovine Heart is a biological material or organic compound intended for use in life science research. It is available in various quantities, including 1 KU, 5 KU, and 10 KU.
- Suitable for life science research applications.
- Available in multiple unit sizes for flexibility.
- Product ships at room temperature within the continental US.
- Comprehensive documentation including data sheet, sds, coa, and handling instructions is available.
Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | 99.8% | 327.89 g/mol | C21H26ClN | 50 MG
Melitracen hydrochloride is the hydrochloride salt of melitracen, supplied as a high-purity research standard for analytical, pharmacological, and formulation studies. It is a white to off-white solid (CAS 10563-70-9) with defined solubility and storage recommendations to support reproducible results.
- High purity suitable for analytical and pharmacological research.
- White to off-white solid with consistent physical properties.
- Soluble in water and DMSO; may require sonication.
- Store solid at 4°C, sealed and protected from moisture; solutions at -80°C (long term) or -20°C (short term).
- Supplied in small pack sizes convenient for assay and preclinical work.