Carboximidamides
Medchemexpress LLC Ask1-in-2 | 2541792-70-3 | 99.6% | 364.38 g·mol⁻¹ | C19H17FN6O | 5 MG
ASK1-IN-2 is a small-molecule, orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 32.8 nM. It is supplied as a white to off-white solid and is available in multiple package sizes and as DMSO solutions for research use; preclinical studies report activity in dextran sulfate sodium (DSS)-induced ulcerative colitis models.
- Potent ASK1 inhibition (IC50 32.8 nM).
- Orally active compound demonstrated in preclinical models.
- Shown to improve DSS-induced ulcerative colitis in mice.
- Blocks ASK1-p38/JNK signaling and reduces inflammatory cytokines.
- High purity (99.6%) and solid, white to off-white physical form.
- Available as solid, solid + solvent, and solution formats for flexible use.
- Powder storage: -20°C for long-term stability; solvent storage guidelines provided.
eMolecules 50-01-1 | Guanidine hydrochloride | Chem-Impex | MFCD00013026 | 95.530 | CH6ClN3 | 99.000 | Cl.NC(N)=N | 100g | 322126114
Guanidine hydrochloride | Chem-Impex | 50-01-1 | MFCD00013026 | 95.530 | CH6ClN3 | 99.000 | Cl.NC(N)=N | 100g | 322126114
Medchemexpress LLC Steviol | 471-80-7 | 318.45 | 5 MG
Steviol is the main metabolite of steviol glycosides and an inhibitor of AQP2/CFTR. It slows down renal cyst growth by inhibiting CFTR activity, reducing AQP2 expression, and promoting AQP2 and CFTR degradation. It can be used in polycystic kidney disease research.
- Main metabolite of steviol glycosides
- Inhibitor of AQP2/CFTR
- Slows down the growth of renal cysts
- Inhibits CFTR activity
- Reduces AQP2 expression
- Promotes degradation of AQP2 and CFTR
- Can be used in polycystic kidney disease research
- Exerts diuretic, natriuretic, kaliuretic effects
- Inhibits renal tubular reabsorption of glucose
eMolecules 1362243-70-6 | Medchem Express | Fluorizoline | 5mg | 572596564 | HY-114989 | 362.19 | C15H8Cl2F3NS
Ambeed | 56-Difluoroindole | 100mg | 521390953 | A100948 | 169674-01-5 | MFCD01075212 | 153.132 | C8H5F2N
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Medchemexpress LLC BX430 | 688309-70-8 | 99.2% | 413.11 | 1 ML
BX430 is a potent and selective noncompetitive allosteric human P2X4 receptor channels antagonist with an IC50 of 0.54 μM. It exhibits species specificity and is used for chronic pain and cardiovascular disease.
- Has virtually no functional impact on all other P2X subtypes (P2X1-P2X3, P2X5, and P2X7).
- Potent antagonist of zebrafish P2X4.
- Reduces intracellular calcium rise evoked by ATP in human P2X4-expressing cells.
- Markedly reduces the amplitude of ATP-evoked intracellular calcium responses in THP-1 cells.
Apexbio Technology LLC Allantoin 97-59-6 100mg
Allantoin (CAS 97-59-6) is a naturally occurring diureide of glyoxylic acid commonly isolated from the dried tubers of Dioscorea opposite Thunb This small molecule is known for its role in facilitating cell proliferation and promoting tissue repair attributed to its ability to modulate cellular response to injury and oxidative stress Allantoin is widely utilized in biomedical research for investigating mechanisms of wound healing anti-inflammatory responses and skin barrier restoration Proper storage in a sealed cool and dry environment is recommended to maintain compound stability
Medchemexpress LLC ((bis(3-chloro-4-methylphenyl)boraneyl)oxy)(3-hydroxypyridin-2-yl)methanone | 872044-70-7 | MFCD18251581 | 99.0% | 400.06 g/mol | C20H16BCl2NO3 | 5 MG
AN0128 is a boron-containing antibacterial and anti-inflammatory research compound with demonstrated in vitro activity against several Gram-positive bacteria. It is intended for use in preclinical research on periodontal and cutaneous diseases and is supplied as a solid with high purity; handle protected from light.
Medchemexpress LLC Parishin C | 174972-80-6 | MFCD29059903 | 99.8% | 728.65 g·mol^-1 | C32H40O19 | 10 MG
Parishin C is a parishin derivative isolated from Gastrodia elata and supplied as a high-purity analytical standard for research and analytical applications. It may exhibit antioxidant properties.
- High purity of 99.8%.
- Molecular formula C32H40O19 and molecular weight 728.65 g·mol^-1.
- Supplied as a 10 MG vial for analytical use.
- Intended for research and analytical assays, including biochemical characterization and reference standard use.
- Isolated from Gastrodia elata and reported to have antioxidant activity.
eMolecules 50-01-1 | Guanidine hydrochloride | Chem-Impex | MFCD00013026 | 95.530 | CH6ClN3 | 99.000 | Cl.NC(N)=N | 1kg | 342450116
Guanidine hydrochloride | Chem-Impex | 50-01-1 | MFCD00013026 | 95.530 | CH6ClN3 | 99.000 | Cl.NC(N)=N | 1kg | 342450116
eMolecules 50-01-1 | Guanidine hydrochloride | Chem-Impex | MFCD00013026 | 95.530 | CH6ClN3 | 99.000 | Cl.NC(N)=N | 100g | 322126116
Guanidine hydrochloride | Chem-Impex | 50-01-1 | MFCD00013026 | 95.530 | CH6ClN3 | 99.000 | Cl.NC(N)=N | 100g | 322126116
Matrix Scientific 1-METHYLGUANIDINE HYDROCHLOR-5
1-methylguanidine Hydrochloride Mf C2h8cln3 Mw 109.56 Cas 21770-81-0 Mdl MFCD00012576