Carboximidamides
![Medchemexpress LLC Pyrrolo[3,4-b]pyrrole-5(1H)-carboxamide, N-[4-[(3-ethynylphenyl)amino]-7-methoxy-6-quinazolinyl] | 1353644-70-8 | 99.7% | 442.51 g/mol | C25H26N6O2 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000243817.png-250.jpg)
Medchemexpress LLC Pyrrolo[3,4-b]pyrrole-5(1H)-carboxamide, N-[4-[(3-ethynylphenyl)amino]-7-methoxy-6-quinazolinyl] | 1353644-70-8 | 99.7% | 442.51 g/mol | C25H26N6O2 | 50 MG
Theliatinib is a potent, ATP-competitive, orally active, and highly selective epidermal growth factor receptor (EGFR) inhibitor provided for research use in preclinical biochemical and cell-based studies.
- Potent ATP-competitive EGFR inhibitor with low-nanomolar activity.
- High chemical purity (99.72%).
- Molecular weight 442.51 g/mol; formula C25H26N6O2.
- Soluble in DMSO (~1 mg/mL) with recommended warming and pH adjustment.
- Stable when stored under recommended powder and solution conditions.
- Suitable for studies of wild-type and mutant EGFR signaling.
Chem-Impex International, Inc. 1,1,3,3-Tetramethylguanidine | MFCD00008323 | 250ML
1,1,3,3-Tetramethylguanidine, MFCD00008323, 250ML
Selleck Chemical LLC Allantoin S3856-1g
Allantoin (Glyoxyldiureide 5-Ureidohydantoin) produced from uric acid is a major metabolic intermediate in most organisms including animals plants and bacteria
Medchemexpress LLC Allantoin | 97-59-6 | MFCD00005260 | 158.12 | 5 G
Allantoin is a widely recognized skin conditioning agent that supports healthy skin and stimulates new tissue growth. It exhibits anti-oxidative and anti-inflammatory properties, and has been observed to attenuate apoptosis and cytotoxicity, enhancing the viability of STZ-induced β-cells in a dose-dependent manner. Additionally, allantoin decreases caspase-3 levels, boosts phosphorylated B-cell lymphoma 2 (Bcl-2) expression, and activates imidazoline 3 (I3) receptors.
- Skin conditioning agent
- Promotes healthy skin and new tissue growth
- Exhibits anti-oxidative and anti-inflammatory activities
- Attenuates apoptosis and cytotoxicity
- Increases viability of STZ-induced β-cells
- Activates imidazoline 3 (I3) receptors
Selleck Chemical LLC Clonidine HCl S2458-1g
Clonidine HCl(Kapvay) is a direct-acting 2 adrenergic agonist with an ED50 of 0 02 0 01 mg/kg
Medchemexpress LLC Creatine Kinase (CPK/CK), Bovine Heart | 9001-15-4 | 1 KU
Creatine Kinase (CPK/CK), Bovine Heart is a biological material or organic compound that can be used in life science research. It is for research use only and not sold to patients.
- Biological material
- Organic compound
- Used in life science research
Alkali Scientific Creatine Phosphate Disodium Salt Tetrahydrate, 1 Kg
Creatine Phosphate Disodium Salt Tetrahydrate is a high-purity compound used in energy metabolism studies. The disodium salt tetrahydrate form is highly soluble and ideal for use in biochemical assays, particularly in laboratories studying muscle metabolism and energy production. Creatine phosphate plays a crucial role in regenerating ATP, the primary energy source for cellular functions, especially in muscle cells. It is widely used in clinical chemistry, sports science, and metabolic research. This compound is typically used in laboratory preparations, clinical research, and the development of energy metabolism studies to assess creatine levels in biological systems.
Selleck Chemical LLC Clonidine HCl S2458-50mg
Clonidine HCl(Kapvay) is a direct-acting 2 adrenergic agonist with an ED50 of 0 02 0 01 mg/kg
Medchemexpress LLC Creatine kinase MB (rCK-MB), recombinant human (CK-MB) | 9001-15-4 | 100 UG
Creatine Kinase MB (rCK-MB), Recombinant Human (CK-MB) is a biological material or organic compound that can be used in life science research. This product is intended for research use only.
- Appearance: liquid, colorless to light yellow.
- Enzyme activity: > 400 U/mL.
- Unit definition: one unit is defined as the amount of enzyme that catalyzes the transphosphorylation of one micromole of phosphate from creatine phosphate to ADP per minute at 37°C.
- Shipping with dry ice.
- Store under recommended conditions in the certificate of analysis.
Medchemexpress LLC Dryocrassin ABBA | 12777-70-7 | 820.83 | 5 MG
Dryocrassin ABBA (Dryocrassin) is an orally active phloroglucinol derivative extracted from *Phyllopteris officinalis*. It demonstrates antitumor and antiviral activity, and induces apoptosis of human hepatocellular carcinoma cells via a mitochondrial pathway mediated by Caspase.
- Possesses antitumor activity
- Exhibits antiviral activity
- Induces apoptosis in human hepatocellular carcinoma cells via a mitochondrial pathway
- Inhibits S. aureus SrtA (sortase A) activity
Medchemexpress LLC Ask1-in-2 | 2541792-70-3 | 99.6% | 364.38 g·mol⁻¹ | C19H17FN6O | 5 MG
ASK1-IN-2 is a small-molecule, orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 32.8 nM. It is supplied as a white to off-white solid and is available in multiple package sizes and as DMSO solutions for research use; preclinical studies report activity in dextran sulfate sodium (DSS)-induced ulcerative colitis models.
- Potent ASK1 inhibition (IC50 32.8 nM).
- Orally active compound demonstrated in preclinical models.
- Shown to improve DSS-induced ulcerative colitis in mice.
- Blocks ASK1-p38/JNK signaling and reduces inflammatory cytokines.
- High purity (99.6%) and solid, white to off-white physical form.
- Available as solid, solid + solvent, and solution formats for flexible use.
- Powder storage: -20°C for long-term stability; solvent storage guidelines provided.
Medchemexpress LLC Ccr4-351 | 2174938-70-4 | MFCD32701932 | 99.0% | 500.42 g/mol | C24H27Cl2N7O | 5 MG
CCR4-351 is a small-molecule, orally active CCR4 antagonist used for preclinical research. It shows potent and selective activity in cellular assays and has demonstrated antitumor efficacy in animal models. For research use only; consult the supplier datasheet and safety documents for handling, storage, and dosing guidance.
- Orally active and selective CCR4 antagonist.
- Demonstrated antitumor activity in vivo.
- Potent activity in cellular assays (low-nanomolar IC50 reported).
- High chemical purity suitable for research applications.
- Provided as a solid form for in vitro and in vivo studies.
- Refer to the product datasheet and safety documents for handling and dosing.