Carboximidamides
Medchemexpress LLC Fluorizoline 50mg | 1362243-70-6 | 362.20 g/mol | C15H8Cl2F3NS | 50 MG
Fluorizoline is a small-molecule antitumor agent that selectively binds prohibitin 1 (PHB1) and prohibitin 2 (PHB2) to induce apoptosis. It reduces chronic lymphocytic leukemia (CLL) cell viability through upregulation of NOXA and BIM and demonstrates activity independent of p53. The compound is supplied as a solid powder for preclinical research.
- High purity (99.77%) suitable for research assays.
- Molecular weight 362.20 g/mol and formula C15H8Cl2F3NS.
- Soluble in DMSO (50 mg/mL); may require ultrasonic treatment.
- Powder stable at -20°C for long-term storage.
- Direct binder of prohibitin proteins; useful for apoptosis and mechanism-of-action studies.
![eMolecules 1260850-70-1 | Ambeed | 3-Bromoimidazo[12-b]pyridazin-6-ylamine | 250mg | 490506710 | A134690 | MFCD11520885 | 213.038 | C6H5BrN4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502448762.PNG-250.jpg)
eMolecules 1260850-70-1 | Ambeed | 3-Bromoimidazo[12-b]pyridazin-6-ylamine | 250mg | 490506710 | A134690 | MFCD11520885 | 213.038 | C6H5BrN4
Ambeed | 3-Cyano-3-phenylpropanoic acid | 250mg | 600839234 | A390691 | 14387-18-9 | MFCD03032627 | 175.187 | C10H9NO2
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eMolecules 64513-70-8 | 2-(CYCLOPROPANECARBOXAMIDO)ACETIC ACID | AstaTech | MFCD01724840 | 143.142 | C6H9NO3 | 95.000 | OC(=O)CNC(=O)C1CC1 | 0.25g | 384830441
2-(CYCLOPROPANECARBOXAMIDO)ACETIC ACID | AstaTech | 64513-70-8 | MFCD01724840 | 143.142 | C6H9NO3 | 95.000 | OC(=O)CNC(=O)C1CC1 | 0.25g | 384830441
Alkali Scientific Guanidine Hydrochloride, 500 G
Guanidine Hydrochloride, available in a 500g format, is a powerful chaotropic agent used extensively in molecular biology for protein denaturation and nucleic acid isolation. It disrupts protein structures by breaking hydrogen bonds and other stabilizing interactions, making it ideal for extracting nucleic acids or for use in protein unfolding studies. This reagent is commonly used in protocols for RNA, DNA, and protein purification, especially in the preparation of samples for further biochemical analysis. Its versatility extends to use in protein-protein interaction studies and structural analysis of biomolecules in research labs.
Medchemexpress LLC Creatine Kinase (CPK/CK), Bovine Heart | 9001-15-4 | 1 KU
Creatine Kinase (CPK/CK), Bovine Heart is a biological material or organic compound that can be used in life science research. It is for research use only and not sold to patients.
- Biological material
- Organic compound
- Used in life science research
Apexbio Technology LLC Guanidine HCl 50-01-1 50g
Guanidine hydrochloride (Guanidine HCl CAS 50-01-1) is a highly alkaline crystalline compound derived from the oxidative metabolism of guanine Functioning primarily as a strong chaotropic agent it disrupts hydrogen bonding and secondary structure in proteins leading to efficient protein denaturation and solubilization Widely utilized in molecular biology and biochemistry Guanidine HCl facilitates protein unfolding for downstream applications such as protein purification refolding studies and RNA extraction protocols where it also serves to inactivate nucleases and other enzymes
Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | 99.8% | 327.89 | C21H26ClN | 100 MG
Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | 99.8% | 327.89 | C21H26ClN | 100 MG
Medchemexpress LLC Creatine kinase MB (rCK-MB), recombinant human (CK-MB) | 9001-15-4 | 100 UG
Creatine Kinase MB (rCK-MB), Recombinant Human (CK-MB) is a biological material or organic compound that can be used in life science research. This product is intended for research use only.
- Appearance: liquid, colorless to light yellow.
- Enzyme activity: > 400 U/mL.
- Unit definition: one unit is defined as the amount of enzyme that catalyzes the transphosphorylation of one micromole of phosphate from creatine phosphate to ADP per minute at 37°C.
- Shipping with dry ice.
- Store under recommended conditions in the certificate of analysis.
Medchemexpress LLC Nardosinone | 23720-80-1 | 250.33 | 5 MG
Nardosinone, isolated from Nardostachys chinensis, is identified as the first enhancer of the neuritogenic action of dbcAMP and staurosporine. It may serve as a pharmacological tool for studying the mechanism of action of nerve growth factor (NGF) and other neuritogenic substances.
- Purity of 99.81%
- Appearance as a white to off-white solid
- Store at 4°C, protected from light; in solvent, store at -80°C for 6 months or -20°C for 1 month
- Soluble in DMSO at 100 mg/mL
- Initial source from plants, Valerianaceae, Nardostachys jatamansi (D. Don) DC.
- Classified as a terpenoid, sesquiterpene
- Exhibits antiinflammatory activity in RAW264.7 cells with an IC50 of 11.1 μM
STA Pharmaceutical ANA 2'-F U amidite | 5 g | CAS 1190089-70-3 | MDL MFCD15145421
ANA 2'-F U amidite is a Amidite reagent (Subcategory: ANA Series) sold by WuXi TIDES. Offered in 5 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 1190089-70-3
- MDL: MFCD15145421
- InChIKey: HQHQPAYRJJMYQX-CPBIVIIKSA-N
- Molecular Weight: 748.789165161
- Molecular Formula: C39H46FN4O8P
- Purity: ≥98%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(NC(C=C5)=O)=O)F)OCCC#N)C(C)C)C
Medchemexpress LLC Dryocrassin ABBA | 12777-70-7 | 820.83 | 5 MG
Dryocrassin ABBA (Dryocrassin) is an orally active phloroglucinol derivative extracted from *Phyllopteris officinalis*. It demonstrates antitumor and antiviral activity, and induces apoptosis of human hepatocellular carcinoma cells via a mitochondrial pathway mediated by Caspase.
- Possesses antitumor activity
- Exhibits antiviral activity
- Induces apoptosis in human hepatocellular carcinoma cells via a mitochondrial pathway
- Inhibits S. aureus SrtA (sortase A) activity
eMolecules 3804-70-4 | Medchem Express | ()-Columbianetin | 5mg | 624169641 | HY-N0363 | MFCD02259437 | 246.262 | C14H14O4
Ambeed | 45-Dichloro-2-methoxybenzaldehyde | 1g | 600838744 | A368868 | 883532-73-8 | MFCD06246853 | 205.030 | C8H6Cl2O2
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Medchemexpress LLC Creatine kinase M-type/CKM protein, mouse (His) | >90.0% | 50UG
Recombinant mouse creatine kinase M-type (CKM) is supplied as a lyophilized, His-tagged protein expressed in E. coli for research use. CKM catalyzes reversible phosphate transfer between ATP and creatine phosphate and supports energy buffering in high-demand tissues. The material is provided with high purity and low endotoxin and is intended for biochemical assays, enzymology, and antibody validation. Store frozen and follow supplier reconstitution recommendations.
- High purity (>90%) as determined by reducing SDS-PAGE.
- Lyophilized formulation for long-term storage and convenient reconstitution.
- Expressed in E. coli with an N-terminal 6xHis tag to facilitate purification.
- Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
- Molecular weight approximately 49.0 kDa, consistent with the CKM isoform.
- Recommended storage at -20°C; stable short term at 4°C after reconstitution.
eMolecules 2490400-70-7 | 3-((Difluoromethyl)sulfonyl)propan-1-amine hydrochloride | ChemScene209.640 | C4H10ClF2NO2S | 98.000 | Cl.NCCCS(=O)(=O)C(F)F | 100mg | 718356374
3-((Difluoromethyl)sulfonyl)propan-1-amine hydrochloride | ChemScene | 2490400-70-7209.640 | C4H10ClF2NO2S | 98.000 | Cl.NCCCS(=O)(=O)C(F)F | 100mg | 718356374
Medchemexpress LLC GDC-0276 50mg | 1494581-70-2 | 50 MG
Selective, orally active NaV1.7 inhibitor research compound intended for preclinical and clinical pharmacology studies. Demonstrates sub-nanomolar potency and favorable pharmacokinetics; supplied as a high-purity small-molecule solid for laboratory use.
- High purity (99.7%).
- Molecular weight 462.58.
- Chemical formula C24H31FN2O4S.
- Reported potency IC50 = 0.4 nM (NaV1.7).
- Supplied quantity 50 MG.