Carboximidamides
Medchemexpress LLC Auda | 479413-70-2 | 98.0% | 392.58 | 1 ML
AUDA (compound 43) is a potent soluble epoxide hydrolase (sEH) inhibitor. It exhibits anti-inflammatory activity, making it suitable for various research applications.
- Potent soluble epoxide hydrolase (sEH) inhibitor
- Exhibits anti-inflammatory activity
- Suitable for research applications
Medchemexpress LLC Nortanshinone | 97399-70-7 | 5 MG
Nortanshinone is a pigment isolated from Dan-Shen, intended for research use only. It has a molecular weight of 280.27 and a chemical formula of C17H12O4. This compound typically appears as a solid, ranging from brown to reddish brown.
- High purity of 98.0%
- Soluble in DMSO at 1.25 mg/mL (4.46 mM)
- Isolated from plants such as Leguminosae and Labiatae
- Classified as a quinone and naphthalene quinone
Medchemexpress LLC AUDA | 479413-70-2 | 98.0% | 392.58 | 100 MG
AUDA is a potent soluble epoxide hydrolase (sEH) inhibitor that exhibits anti-inflammatory activity. It is effective against both mouse and human sEH, with IC50 values of 18 nM and 69 nM respectively.
- Potent soluble epoxide hydrolase (sEH) inhibitor
- Exhibits anti-inflammatory activity
- Suppresses the proliferation of rat VSMCs
- Upregulates COX-2 expression
- Augments the migratory ability of HCAECs
- Increases the adhesion ability of HCAECs
- Reduces TNF-α, MMP-9, and IL-1β expression levels
eMolecules 1016837-70-9 | Ambeed | 2-(2-Bromophenoxy)-NN-dimethylacetamide | 250mg | 728125864 | A1061323 | MFCD09944437 | 258.115 | C10H12BrNO2
Ambeed | 4-Fluoro-3-((trifluoromethyl)sulfonyl)benzene-1-sulfonyl chloride | 250mg | 570568310 | A187776 | 1027345-07-8 | MFCD16883063 | 326.660 | C7H3ClF4O4S2
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Medchemexpress LLC Ask1-in-2 | 2541792-70-3 | MFCD11217007 | 99.6% | C19H17FN6O | 10MG
ASK1-IN-2 is a small-molecule, orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with a reported biochemical IC50 of 32.8 nM. Supplied as a high-purity research chemical (CAS 2541792-70-3; formula C19H17FN6O), it is available as a solid powder and as a 10 mM solution in DMSO for use in in vitro and in vivo preclinical studies, including research into inflammatory conditions such as ulcerative colitis.
- Potent ASK1 inhibition (IC50 32.8 nM).
- Orally active small molecule suitable for in vivo studies.
- High purity (99.6%).
- Available as solid powder and as 10 mM solution in DMSO.
- Suitable for research into inflammatory diseases such as ulcerative colitis.
- Provided with safety data sheet and product documentation.
Medchemexpress LLC 6-methyl-2-((3-phenoxypropylamino)methyl)quinolin-4(1H)-one | 1434515-70-4 | 99.5% | 322.40 | C20H22N2O2 | 50MG
UCSF924 is a potent and selective dopamine D4 receptor (DRD4) partial agonist used as a chemical probe in receptor pharmacology and neuropsychiatric research. It exhibits low-nanomolar activity (EC50 4.2 nM) and is supplied as a high-purity solid with recommended low-temperature storage for long-term stability.
- Potent DRD4 partial agonist (EC50 4.2 nM).
- High selectivity against other G protein-coupled receptors.
- Reported purity 99.53%.
- Molecular formula C20H22N2O2; molecular weight 322.40.
- Available in multiple pack sizes including 50 mg.
- Appearance: white to off-white solid; powder storage recommended at -20°C for long-term stability.
Medchemexpress LLC AN0128 | 872044-70-7 | 98.95% | 400.06 | 50 MG
AN0128 is a boron-containing antibacterial and anti-inflammatory agent. It is effective against various bacteria including *S. aureus*, *S. epidermidis*, *P. acnes*, and *B. subtilis*. This compound can be utilized in the research of periodontal disease and cutaneous diseases, demonstrating strong inhibition of pro-inflammatory cytokines *in vitro* and reduction of inflammatory infiltrate and bone loss *in vivo*.
- Boron-containing antibacterial and anti-inflammatory agent
- Effective against *S. aureus*, *S. epidermidis*, *P. acnes*, and *B. subtilis*
- Utilized for research on periodontal disease and cutaneous diseases
- Inhibits release of pro-inflammatory cytokines (TNF-α, IL-1β) in PBMCs
- Reduces inflammatory infiltrate and bone loss *in vivo*
- Increases bone area and bone volume in experimental periodontitis rat model
- Decreases bone loss and inflammation in experimental periodontitis rat model
STA Pharmaceutical ANA 2'-F U amidite | 1 g | CAS 1190089-70-3 | MDL MFCD15145421
ANA 2'-F U amidite is a Amidite reagent (Subcategory: ANA Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 1190089-70-3
- MDL: MFCD15145421
- InChIKey: HQHQPAYRJJMYQX-CPBIVIIKSA-N
- Molecular Weight: 748.789165161
- Molecular Formula: C39H46FN4O8P
- Purity: ≥98%
- Container Type: 30 mL Glass (28-400)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 50.1 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(NC(C=C5)=O)=O)F)OCCC#N)C(C)C)C
Apexbio Technology LLC Guanidine HCl 50-01-1 10g
Guanidine hydrochloride (Guanidine HCl CAS 50-01-1) is a highly alkaline crystalline compound derived from the oxidative metabolism of guanine Functioning primarily as a strong chaotropic agent it disrupts hydrogen bonding and secondary structure in proteins leading to efficient protein denaturation and solubilization Widely utilized in molecular biology and biochemistry Guanidine HCl facilitates protein unfolding for downstream applications such as protein purification refolding studies and RNA extraction protocols where it also serves to inactivate nucleases and other enzymes
TARGETMOL CHEMICALS INC CP 461 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. CP 461 (UNII-68OJX9I7DT) a specific PDE2A inhibitor is a novel pro-apoptotic compound that inhibits cyclic GMP phosphodiesterase but not cyclooxygenase-1 or -2. CP 461 inhibits the growth of a variety of human tumor cell lines in vitro and selectively induces apoptosis in cancer cell lines but not in normal cells. purity: 99%
Medchemexpress LLC Smap-2 (DT-1154) | 1809068-70-9 | 99.5% | 10 MG
SMAP-2 (DT-1154) is an orally active small-molecule activator of protein phosphatase 2A (PP2A) that exhibits anti-cancer activity in cell and animal models, reducing viability of pancreatic ductal adenocarcinoma cell lines and demonstrating in vivo efficacy.
- Orally active PP2A activator with demonstrated anti-cancer activity.
- High purity (99.5%).
- Molecular weight 532.57 g/mol; formula C27H27F3N2O4S.
- High solubility in DMSO (300 mg/mL) and formulatable for in vivo dosing using recommended protocols.
- Stable as a powder when stored at -20°C and 4°C for indicated durations.
- For research use only; not for human use.