Enamines
Medchemexpress LLC (R)-Nimodipine | 77940-92-2 | 99.9% | 25 MG
(R)-Nimodipine is an orally active, blood-brain barrier-permeable L-type calcium channel blocker with an IC50 of 5 nM. It inhibits corticosterone release by blocking calcium channels on the hypothalamic-pituitary-adrenal axis, reversing immobilization stress-induced memory impairment and behavioral abnormalities. This compound is widely used in studies related to aneurysmal subarachnoid hemorrhage, cerebral ischemia, epilepsy, age-related degenerative neurological diseases, and alcohol intoxication.
- Orally active and blood-brain barrier-permeable
- L-type calcium channel blocker
- Inhibits corticosterone release
- Reverses immobilization stress-induced memory impairment
- Used in research for neurological and cerebrovascular diseases
- Inhibits slow inactivating Ca2+ currents in vitro
- Soluble in DMSO for experimental use
- Provided with in vivo protocols for various formulations
Medchemexpress LLC (S)-Nimodipine | 77940-93-3 | 99.9% | 418.44 | 100 MG
(S)-Nimodipine is an enantiomer of Nimodipine, an orally active, well-tolerated, and light-sensitive dihydropyridine calcium antagonist. It is used in the research of cerebrovascular disorders, targeting the Calcium Channel and involving Membrane Transporter/Ion Channel; Neuronal Signaling pathways.
- Enantiomer of Nimodipine
- Orally active dihydropyridine calcium antagonist
- Used in research of cerebrovascular disorders
- Targets Calcium Channel
- Involves Membrane Transporter/Ion Channel; Neuronal Signaling pathway
Medchemexpress LLC Mirogabalin besylate | 1138245-21-2 | MFCD31631215 | 99.6% | 367.46 g·mol⁻¹ | C18H25NO5S | 1 ML
Mirogabalin besylate is the besylate salt of mirogabalin, a selective ligand for the α2δ subunit of voltage-gated calcium channels used in preclinical research. Supplied as a ready-to-use solution in DMSO, it is intended for in vitro and related laboratory applications. Refer to the safety data sheet for handling and storage instructions.
- 10 mM solution in DMSO, 1 mL vial.
- High purity (99.6%) as supplied.
- Molecular weight 367.46 g·mol⁻¹.
- Molecular formula C18H25NO5S.
- Recommended storage: in solvent -80°C (up to 6 months) or -20°C (up to 1 month); solid 4°C (sealed).
- Intended for research use only.
Medchemexpress LLC PF-562271 besylate | 939791-38-5 | MFCD14105612 | 99.2% | 665.7 g/mol | C27H26F3N7O6S2 | 1 MG
PF-562271 besylate is an ATP-competitive, reversible inhibitor of focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (Pyk2) used as a research tool in cell-signaling and oncology studies. It exhibits potent biochemical activity (FAK IC50 ≈ 1.5 nM; Pyk2 IC50 ≈ 13-14 nM), is supplied as the besylate salt, and is available at high purity for in vitro and in vivo research.
- Potent ATP-competitive, reversible inhibitor of FAK and Pyk2.
- Low nanomolar biochemical potency for target kinases.
- Provided as a besylate salt for improved stability and handling.
- High reported purity suitable for research applications.
- Used in cellular and animal model studies of tumor signaling pathways.
Medchemexpress LLC (R)-Amlodipine | 103129-81-3 | MFCD06809924 | 99.5% | 408.88 g/mol | C20H25ClN2O5 | 10 MG
(R)-Amlodipine is the R-enantiomer of amlodipine, a dihydropyridine L-type calcium channel inhibitor supplied as an off-white to light yellow solid for research use. It is commonly used in pharmacological and formulation studies that require the isolated enantiomer.
- High purity (99.45%).
- Molecular weight 408.88 g/mol.
- Chemical formula C20H25ClN2O5.
- Soluble in DMSO at 100 mg/mL; ultrasonic recommended.
- In vivo formulation protocols yield ≥2.5 mg/mL solubility in listed vehicles.
- Available in small research sizes (e.g., 10 mg).
- Storage: powder -20°C for up to 3 years; in solvent -80°C for 6 months or -20°C for 1 month.
eMolecules 391624-46-7 | (9H-Fluoren-9-yl)Methyl (2-Aminoethyl)Carbamate Hydrochloride | AA Blocks LLC | MFCD00830741 | 318.800 | C17H19ClN2O2 | 0.000 | Cl.NCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 100g | 816441728
(9H-Fluoren-9-yl)Methyl (2-Aminoethyl)Carbamate Hydrochloride | AA Blocks LLC | 391624-46-7 | MFCD00830741 | 318.800 | C17H19ClN2O2 | 0.000 | Cl.NCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 100g | 816441728
Medchemexpress LLC (S)-Nimodipine | 77940-93-3 | 99.9% | 418.44 | 50 MG
(S)-Nimodipine is an enantiomer of Nimodipine. Nimodipine is an orally active, well-tolerated, and light-sensitive dihydropyridine calcium antagonist. It can be used for the research of cerebrovascular disorders.
- Target: Calcium channel
- Pathway: Membrane transporter/ion channel; neuronal signaling
- Application: Research of cerebrovascular disorders
Selleck Chemical LLC PF-562271 Besylate S2672-1g
PF-562271 Besylate is the benzenesulfonate salt of PF-562271 which is a potent ATP-competitive reversible inhibitor of FAK with IC50 of 1 5 nM 10-fold less potent for Pyk2 than FAK and 100-fold selectivity against other protein kinases except for some CDKs Phase 1
Medchemexpress LLC Nimodipine (BAY-e 9736) | 66085-59-4 | 99.9% | 1 G
Nimodipine (BAY-e 9736) is an orally active, well-tolerated, and light-sensitive dihydropyridine calcium antagonist. It can be used for the research of cerebrovascular disorders.
- Orally active
- Well-tolerated
- Light-sensitive
- Dihydropyridine calcium antagonist
- Used for the research of cerebrovascular disorders
Medchemexpress LLC Amlodipine maleate | 88150-47-4 | 99.9% | 5 G
Amlodipine maleate is a dihydropyridine calcium channel blocker that acts as an orally active antianginal agent. It blocks voltage-dependent L-type calcium channels, inhibiting the initial influx of calcium. This compound is used in research for high blood pressure and cancer studies.
- Blocks voltage-dependent L-type calcium channels
- Inhibits initial influx of calcium
- Attenuates uridine 5′-triphosphate (UTP)-induced increases of intracellular calcium
- Inhibits store-operated calcium influx
Med Vet International AmLodipine Besylate Tablets (Norvsac), 10mg, 1000ct
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Amlodipine Besylate Tablets (norvsac), 10mg, 1000ct