Guanidines
FUJIFILM BIOSCIENCES INC Metformin hydrochloride
Metformin Hydrochloride is is one of the biguanides It suppresses glyconeogenesis in the liver facilitates peripheral use of glucose and inhibits glucose absorption from the intestinal tract via activation of AMPK AMP-activated protein kinase resulting in hypoglycemic effects It has been widely used as a drug to treat type 2 diabetes mellitus in clinical practices as showing hypoglycemic effects independent of insulin secretion in the pancreatic b-cell
Medchemexpress LLC Metformin impurity 1 (Standard) | 1674-62-0 | 151.60 | 5 G
Metformin impurity 1 (Standard) is the analytical standard of Metformin impurity 1. This product is intended for research and analytical applications. It is an analytical standard, a reference standard supplied assay, commonly used in qualitative, quantitative, and methodological research experiments.
- Analytical standard for research and analytical applications
- Used in HPLC, GC, and MS experiments
- Reference standard for assay
Medchemexpress LLC 4-(2,6-dioxo-1-propyl-1,2,3,6-tetrahydropurin-8-yl)benzene-1-sulfonic acid | 152529-79-8 | 99.0% | 350.35 g/mol | C14H14N4O5S | 10 MG
PSB-1115 is a selective A2B adenosine receptor antagonist for pharmacological research. It inhibits TNBS-induced acetylcholine contraction in vitro and antagonizes NECA-induced inhibition of mucociliary clearance in vivo.
- Selective A2B adenosine receptor antagonist
- Purity 99.0%
- Molecular weight 350.35 g/mol
- Chemical formula C14H14N4O5S
- CAS number 152529-79-8
- Solubility: DMSO 100 mg/mL; H2O 10 mg/mL
- Storage: -20°C; in solvent -80°C (6 months)
- Intended for research use only
Medchemexpress LLC Metformin (hydrochloride) (Standard) | 1115-70-4 | 100.0% | 165.62 | 50 MG
Metformin (hydrochloride) (Standard) | 1115-70-4 | 100.0% | 165.62 | 50 MG
Medchemexpress LLC 4-(2,6-dioxo-1-propyl-1,2,3,6-tetrahydropurin-8-yl)benzene-1-sulfonic acid | 152529-79-8 | 99.0% | 350.35 | C14H14N4O5S | 50 MG
PSB-1115 is a selective A2B adenosine receptor antagonist supplied as a high-purity solid for research use. It is used in pharmacological and biochemical studies to investigate A2B receptor-mediated effects.
- Selective A2B adenosine receptor antagonist
- High purity (99.0%)
- Solid form; available in multiple sizes including 50 MG
- Molecular weight 350.35; formula C14H14N4O5S
- CAS 152529-79-8
Apexbio Technology LLC PSB 1115 152529-79-8 5mg
PSB 1115 is a selective antagonist targeting the human A2B adenosine receptor It is designed to inhibit receptor-mediated signaling pathways associated with adenosine receptors thereby regulating processes related to inflammation and immune response PSB 1115 exerts its biological activity primarily through antagonism of the A2B adenosine receptor In experimental studies PSB 1115 demonstrates inhibition of acetylcholine-induced contractions triggered by 2 4 6-trinitrobenzene sulfonic acid (TNBS) a commonly used method in gastrointestinal inflammation research Based on these pharmacological properties PSB 1115 holds research potential in investigating inflammatory response immune regulation and mechanisms underlying inflammation-related disorders
Accela Chembio Inc 1 | 1-dimethylbiguanide Hydrochloride | 100g | 1115-70-4 | MFCD00012582 | 96% | Shelf Life: 2340 Days | Light Sensitive/moisture Sensitive
1 | 1-dimethylbiguanide Hydrochloride | 100g | 1115-70-4 | MFCD00012582 | 96% | Shelf Life: 2340 Days | Light Sensitive/moisture Sensitive
Sigma Aldrich Fine Chemicals Biosciences Metformin Related Compound30mg
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Apexbio Technology LLC Metformin 657-24-9 25mg
Metformin (CAS 657-24-9) is a biguanide compound widely employed as an antihyperglycemic agent in type II diabetes research Its primary mechanism involves enhancing insulin sensitivity in peripheral tissues and reducing hepatic gluconeogenesis leading to lower circulating glucose levels without directly inducing hypoglycemia Metformin is also associated with decreased fasting plasma insulin concentrations and modest weight reduction These properties make it a valuable small molecule for investigating metabolic regulation insulin resistance and therapeutic strategies for obesity-associated metabolic disorders in preclinical and clinical studies
Medchemexpress LLC BioE-1115 | 1268863-35-9 | >98.2% | 1 ML
BioE-1115 is a highly selective and potent PAS kinase (PASK) inhibitor with an IC50 of ~4 nM. It also acts as a potent casein kinase 2α inhibitor with an IC50 of ~10 μM. This compound is intended for research use only.
- Highly selective and potent PAS kinase inhibitor
- Potent casein kinase 2α inhibitor
- Reduces SREBP activity without affecting cell morphology or growth rate
- Decreases insulin resistance, hepatic and serum TAG, and serum glucose in animal models
- Suppresses expression of SREBP-1c target genes
Medchemexpress LLC Phenylbiguanide hydrochloride | 55-57-2 | MFCD00035040 | 99.8% | 213.67 g/mol | C8H12ClN5 | 10 G
Phenylbiguanide hydrochloride is the hydrochloride salt of phenylbiguanide, a selective 5-HT3 receptor agonist supplied as a high-purity research chemical for in vitro pharmacology and neuroscience studies. The material is characterized with standard identifiers, purity specification, and storage guidance for laboratory use.
- Selective 5-HT3 receptor agonist with an EC50 of 3.0 ± 0.1 μM.
- Chemical identifiers: CAS 55-57-2; formula C8H12ClN5; molecular weight 213.67 g/mol.
- High purity solid (≈99.8%) suitable for analytical and pharmacological assays.
- Available in multiple lab-scale pack sizes (10 G-100 G) for research workflows.
- Storage: store at room temperature up to 3 years; in solvent, -80 °C (2 years) or -20 °C (1 year).
- For research use only; not for human or veterinary use.
Med Vet International Metformin Hcl 500mg, 100 Tablets
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Metformin HCL 500mg, 100 Tablets
Medchemexpress LLC Phenylbiguanide | 55-57-2 | MFCD00035040 | 100.0% | 213.67 g/mol | C8H12ClN5 | 100 G
Phenylbiguanide hydrochloride is a research-grade small molecule used as a selective agonist of the 5-HT3 receptor in pharmacology and neuronal signaling studies. It exhibits an EC50 of approximately 3.0 μM and has documented solubility and stability data suitable for laboratory use.
- Selective 5-HT3 receptor agonist (EC50 ≈ 3.0 μM).
- Chemical identity: CAS 55-57-2; formula C8H12ClN5; molecular weight 213.67 g/mol.
- High purity for research applications (COA reports 99.96%).
- Soluble in DMSO (≈40 mg/mL); formulations reported for in vivo dosing.
- Stable as solid at room temperature; defined solvent storage conditions available.
- Suitable for GPCR and neuronal signaling assays and related pharmacology studies.
Med Vet International Metformin, Er, 500mg, 500 Tablets
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Metformin, ER, 500Mg, 500 Tablets