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Guanidine is a compound with a carbon atom bonded to two nitrogen atoms via singles bonds, and one nitrogen atom via double bond in the following formula: HNC(NH2)2. Guanidine can be considered the nitrogen analogue of carbonic acid.
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Metformin impurity 1 is a chemical product from MedChemExpress, identified by CAS number 1674-62-0 and molecular weight 151.60. It is intended for research use in laboratory settings.
White to off-white solid appearance.
Purity of at least 97.0%.
Stable under recommended storage conditions.
Melting point range of 148-151 °C.
Recommended storage at 4°C, sealed, away from moisture and light.
Harmful if swallowed.
For research use only.
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PSB 1115 is a selective antagonist targeting the human A2B adenosine receptor It is designed to inhibit receptor-mediated signaling pathways associated with adenosine receptors thereby regulating processes related to inflammation and immune response PSB 1115 exerts its biological activity primarily through antagonism of the A2B adenosine receptor In experimental studies PSB 1115 demonstrates inhibition of acetylcholine-induced contractions triggered by 2 4 6-trinitrobenzene sulfonic acid (TNBS) a commonly used method in gastrointestinal inflammation research Based on these pharmacological properties PSB 1115 holds research potential in investigating inflammatory response immune regulation and mechanisms underlying inflammation-related disorders
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Metformin hydrochloride (Metformin HCl CAS 1115-70-4) is a widely studied small molecule employed in biomedical research primarily for investigating glucose metabolism and type 2 diabetes mechanisms It acts through selective inhibition of hepatic gluconeogenesis without directly increasing insulin secretion The molecular targets include activation of AMP-activated protein kinase (AMPK) subsequently suppressing acetyl-CoA carboxylase (ACC) activity attenuating lipid biosynthesis and promoting fatty acid oxidation Additionally metformin inhibits mitochondrial glycerophosphate dehydrogenase (mGPD) changing cellular redox status and reducing lactate-driven gluconeogenesis pathways Key research applications of Metformin HCl include studies on glucose homeostasis metabolic disorders and AMPK signaling cascades
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Biguanide is an orally active antihyperglycemic research reagent used to investigate mitochondrial metabolism and insulin signaling. It inhibits mitochondrial ATP production and activates the LKB1-AMPK pathway, altering cellular energy homeostasis.
Used to study mitochondrial metabolism and AMPK signaling.
Inhibits mitochondrial ATP production.
Enhances insulin-receptor activation and downstream signaling.
Typical purity 98.1% for research use.
Provided as a solid suitable for in vitro and in vivo model studies.
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Biguanide is a small-molecule antihyperglycemic research reagent (CAS 56-03-1) that inhibits mitochondrial ATP production, activates the LKB1-AMPK signaling pathway, and enhances insulin-receptor signaling. It is intended for research use only.
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PSB-1115 is a selective A2B adenosine receptor antagonist supplied for research use to investigate A2B-mediated signaling and physiological responses. It has documented activity in TNBS-induced contraction models and is provided in solid and solution formats for experimental applications.
Selective A2B adenosine receptor antagonist.
Research-use compound for A2B receptor studies.
Purity 99.0%.
Molecular formula C14H14N4O5S; molecular weight 350.35.
CAS number 152529-79-8.
Available in solid 5 mg and solution 10 mM 1 mL in DMSO.
Store at -20°C; protect from light. In solvent: -80°C for 6 months, -20°C for 1 month.
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Metformin impurity 1 (Standard) is the analytical standard of Metformin impurity 1. This product is intended for research and analytical applications. The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Intended for research and analytical applications.
Analytical standard, suitable for reference standard supplied assay.
Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
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