Nitrogen mustard compounds
Medchemexpress LLC Tas4464 | 1848959-10-3 | 99.2% | 10 MG
TAS4464 is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE) with an IC50 of 0.955 nM. This compound inhibits cullin neddylation, leading to the accumulation of CRL substrates such as CDT1, p27, and phosphorylates IκBα in various human cancer cell lines.
- Highly potent and selective inhibitor of NEDD8 activating enzyme (NAE)
- Inhibits cullin neddylation
- Induces accumulation of CRL substrates such as CDT1, p27, and phosphorylates IκBα in 47 human cancer cell lines
eMolecules 1801-10-1 | 3-(Trifluoromethyl)benzamide | Ambeed | MFCD00014802 | 189.137 | C8H6F3NO | 98.000 | NC(=O)c1cccc(c1)C(F)(F)F | 1mg | 761204476
3-(Trifluoromethyl)benzamide | Ambeed | 1801-10-1 | MFCD00014802 | 189.137 | C8H6F3NO | 98.000 | NC(=O)c1cccc(c1)C(F)(F)F | 1mg | 761204476
Medchemexpress LLC Senkyunolide A | 63038-10-8 | MFCD16660665 | 99.3% | 192.26 g/mol | C12H16O2 | 10 MG
Senkyunolide A is a phthalide-class natural product supplied as a research-grade analytical standard, reported to have anticancer and neuroprotective activities and commonly used in biochemical and cellular studies.
- High purity (~99.3%), suitable for analytical and biological research.
- Molecular formula C12H16O2, molecular weight 192.26 g/mol.
- Available in small research quantities (e.g., 10 MG) for lab-scale experiments.
- Appearance: colorless to light yellow liquid; density ~1.1 g/cm3.
- Storage: store at -80°C, protect from light, under inert gas when required.
eMolecules 3302-10-1 | 3,5,5-Trimethylhexanoicacid | Ambeed | MFCD00020507 | 158.241 | C9H18O2 | 98.000 | CC(CC(O)=O)CC(C)(C)C | 100g | 624121817
3,5,5-Trimethylhexanoicacid | Ambeed | 3302-10-1 | MFCD00020507 | 158.241 | C9H18O2 | 98.000 | CC(CC(O)=O)CC(C)(C)C | 100g | 624121817
Medchemexpress LLC β-catenin-IN-2 | 1458664-10-2 | 99.6% | 255.29 | 50 MG
β-catenin-IN-2 is a potent β-catenin inhibitor, also known as Compound H1B1. It is utilized in the study of colorectal cancer, where it suppresses the transcriptional activity of β-catenin/Tcf-4 in HCT116 cells in a dose-dependent manner at concentrations of 10-40 μM.
- Solid appearance with pink to red color
- High purity of 99.6%
- Molecular weight of 255.29
- Formula: C15H14FN3
- Inhibits β-catenin/Tcf-4 transcriptional activity
- Used in colorectal cancer research
Medchemexpress LLC Metarrestin | 1443414-10-5 | 99.9% | 50 MG
Metarrestin is a small-molecule perinucleolar compartment inhibitor provided as a high-purity research compound for in vitro and in vivo studies investigating nucleolar structure and metastasis.
- Provides high purity (99.9%).
- Molecular formula C31H30N4O and molecular weight 474.60 g/mol.
- Available in solid and solution formats for flexibility in experiments.
- Suitable for use in biochemical, cell-based, and pharmacokinetic studies.
- Recommended storage: powder at -20°C; in solvent at -80°C.
Medchemexpress LLC 1-(2-chloroethyl)-3-((1R,4R)-4-hydroxycyclohexyl)-1-nitrosourea-d4 | 00-00-0 | 99.0% | 253.72 | C9H12D4ClN3O3 | 5 MG
Deuterium-labeled trans-4'-Hydroxy CCNU Lomustine-d4 is a research-grade labeled analogue of trans-4'-Hydroxy lomustine intended for use as a tracer and internal standard in quantitative analytical methods. The product is supplied as a high-purity solid in a 5 MG vial and requires cold storage to maintain stability.
- Deuterium-labeled internal standard for NMR, GC-MS, and LC-MS.
- High purity (99.0%).
- Solid, white to off-white appearance.
- Suitable as a tracer for pharmacokinetic and metabolic studies.
- Powder storage: -20°C for long-term stability; in solvent: -80°C for short-term stability.
- Supplied as a 5 MG vial for laboratory use.
eMolecules 407-24-9 | Bistrifluoroacetamide | Combi-Blocks, Inc. | MFCD00013564 | 209.047 | C4HF6NO2 | 98.000 | FC(F)(F)C(=O)NC(=O)C(F)(F)F | 25g | 586077145
Bistrifluoroacetamide | Combi-Blocks, Inc. | 407-24-9 | MFCD00013564 | 209.047 | C4HF6NO2 | 98.000 | FC(F)(F)C(=O)NC(=O)C(F)(F)F | 25g | 586077145
Medchemexpress LLC N-Methylmoranoline | 69567-10-8 | 177.20 | 10 MG
N-Methylmoranoline is an alpha-glucosidase inhibitor. It appears as a white to off-white solid.
- Functions as an alpha-glucosidase inhibitor
- Suitable as a reference compound
- Powder stable for 3 years at -20°C
- In solvent stable for 6 months at -80°C, or 1 month at -20°C
eMolecules 1122-69-6 | 2-ETHYL-6-METHYLPYRIDINE | AstaTech | MFCD00023531 | 121.183 | C8H11N | 97.000 | CCc1cccc(C)n1 | 0.25g | 721956956
2-ETHYL-6-METHYLPYRIDINE | AstaTech | 1122-69-6 | MFCD00023531 | 121.183 | C8H11N | 97.000 | CCc1cccc(C)n1 | 0.25g | 721956956
Chem-Impex International, Inc. N,N-Bis(2-chloroethyl)-p-toluenesulfonamide | MFCD00018944 | 25G
N,N-Bis(2-chloroethyl)-p-toluenesulfonamide, MFCD00018944, 25G
Medchemexpress LLC ZL0580 | 2377151-10-3 | 99.4% | 532.53 | 100 MG
ZL0580, a structurally close analog of ZL0590, induces epigenetic suppression of HIV via selectively binding to BD1 domain of BRD4. It induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter.
- Induces epigenetic suppression of HIV
- Selectively binds to BD1 domain of BRD4
- Inhibits Tat transactivation and transcription elongation
- Induces repressive chromatin structure at the HIV promoter
- Suppresses HIV in primary CD4+ T cells
- Exhibits low toxicity in cell viability assays
Medchemexpress LLC Flesinoxan | 98206-10-1 | 99.9% | 100 MG
Flesinoxan is a selective 5-hydroxytryptamine 1A (5-HT1A) receptor agonist provided as a high-purity research standard. It is intended for receptor pharmacology, in vitro assays, and analytical applications; molecular formula C22H26FN3O4, molecular weight 415.46.
- Selective 5-HT1A receptor agonist for pharmacology studies.
- High reported purity (99.9%) suitable for analytical applications.
- Available in research-scale pack sizes for laboratory use.
- Provided as a DMSO solution option for assay preparation.
- Suitable as an analytical standard for in vitro assays.