Nitrogen mustard compounds

Medchemexpress LLC Swertisin | 6991-10-2 | 1 MG

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Swertisin is an oral adenosine A1 receptor antagonist and an SGLT2 inhibitor. It possesses anti-diabetic and antioxidant properties, inhibits HBV, and improves cognitive and memory impairments.

• Acts as an oral adenosine A1 receptor antagonist
• Functions as an SGLT2 inhibitor
• Possesses anti-diabetic properties
• Exhibits antioxidant properties
• Inhibits HBV
• Improves cognitive and memory impairments

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Medchemexpress LLC Swertisin | 6991-10-2 | 5 MG

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Swertisin is an oral adenosine A1 receptor antagonist and an SGLT2 inhibitor. It exhibits anti-diabetic and antioxidant properties, inhibits HBV, and improves cognitive and memory impairments in mice.

• Acts as an oral adenosine A1 receptor antagonist and SGLT2 inhibitor
• Exhibits anti-diabetic and antioxidant properties
• Inhibits HBV
• Improves cognitive and memory impairments
• Inhibits glucose uptake in HEK293 cells
• Suppresses HBsAg, HBeAg, and HBV DNA levels
• Reduces SGLT2 expression and lowers blood sugar in vivo

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Medchemexpress LLC β-catenin-IN-2 | 1458664-10-2 | 99.6% | C15H14FN3 | 10MG

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β-catenin-IN-2 (Compound H1B1) is a small-molecule inhibitor of β-catenin intended for preclinical research, particularly studies of colorectal cancer and Wnt/β-catenin signaling. The compound is characterized by CAS 1458664-10-2, molecular formula C15H14FN3, molecular weight 255.29, and is supplied with analytical documentation for research use.

• Potent β-catenin inhibitor suitable for cellular and biochemical assays.
• Reported applicability in colorectal cancer research.
• High purity (99.6%) for reliable experimental results.
• Characterized with COA, HNMR, and LCMS data available.
• Small-molecule properties: molecular weight 255.29, formula C15H14FN3.

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Medchemexpress LLC Beta-catenin-IN-2 | 1458664-10-2 | 99.55% | 255.29 | 100 MG

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Beta-catenin-IN-2 (Compound H1B1) is a potent β-catenin inhibitor used for the study of colorectal cancer. It suppresses the transcriptional activity of β-catenin/Tcf-4 in HCT116 cells in a dose-dependent manner at concentrations of 10-40 μM. The product is a solid, pink to red in color. It is soluble in DMSO at 83.33 mg/mL (326.41 mM).

• Potent β-catenin inhibitor
• Suppresses transcriptional activity of β-catenin/Tcf-4
• Used for the study of colorectal cancer
• Solid, pink to red in color
• Soluble in DMSO

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Medchemexpress LLC β-catenin-IN-2 | 1458664-10-2 | 99.6% | 255.29 | 50 MG

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β-catenin-IN-2 is a potent β-catenin inhibitor, also known as Compound H1B1. It is utilized in the study of colorectal cancer, where it suppresses the transcriptional activity of β-catenin/Tcf-4 in HCT116 cells in a dose-dependent manner at concentrations of 10-40 μM.

• Solid appearance with pink to red color
• High purity of 99.6%
• Molecular weight of 255.29
• Formula: C15H14FN3
• Inhibits β-catenin/Tcf-4 transcriptional activity
• Used in colorectal cancer research

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Medchemexpress LLC 2'-O-Methylisoliquiritigenin | 51828-10-5 | 270.28 | 5 MG

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2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA, and GABA pathways, though its effect on the NE pathway is not significant. This compound has shown sedative-hypnotic and anxiolytic effects in mice studies and acts on 5-HT, Dopamine, and GABA Receptors, engaging GPCR/G Protein and Neuronal Signaling pathways. It is intended for research use only.

• Isolated from Arachis species.
• Up-regulates 5-HT, NE, DA, and GABA pathways.
• Acts on 5-HT Receptor, Dopamine Receptor, and GABA Receptor.
• Engages GPCR/G Protein and Neuronal Signaling pathways.
• Has sedative-hypnotic and anxiolytic effects.
• Appears as a solid with a light yellow to yellow color.

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eMolecules​ AstaTech / 2-([11-BIPHENYL]-2-YL)ACETONITRILE / 1g / 493153604 / 34109 / 98.000 / 19853-10-2 / MFCD00060294 / 193.249 / C14H11N

AstaTech / 2-([11-BIPHENYL]-2-YL)ACETONITRILE / 1g / 493153604 / 34109 / 98.000 / 19853-10-2 / MFCD00060294 / 193.249 / C14H11N

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Medchemexpress LLC 2-chloroethyl (2-chloroethyl)phosphonate | 17378-30-2 | MFCD24393365 | >95.0% | 206.99 | C4H9Cl2O3P | 10 MG

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2-Chloroethyl (2-chloroethyl)phosphonate is an organophosphorus compound used as an intermediate in organic synthesis. The compound is identified by CAS 17378-30-2 and is characterized by the molecular formula C4H9Cl2O3P and a molecular weight of 206.99 g/mol (manufacturer datasheet).

• Used as a building block or intermediate in organic synthesis.
• Organophosphorus chemical class with a phosphoryl functionality.
• CAS number 17378-30-2 for unambiguous identification.
• Molecular formula C4H9Cl2O3P, molecular weight 206.99 g/mol.
• Reported purity >95% (HPLC) from analytical standards vendors.
• Available in small laboratory quantities suitable for research use.

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Medchemexpress LLC Cdc25b-in-1 | 2374831-10-2 | 98.1% | 321.37 g/mol | C20H19NO3 | 10MG

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CDC25B-IN-1 is a small-molecule research inhibitor of the cell division cycle 25B (CDC25B) phosphatase, referred to in the literature as compound 4a. It is provided as a 10 mg research sample (CAS 2374831-10-2) for biochemical and cellular studies targeting CDC25B-mediated signaling.

• Potent CDC25B inhibition with reported Ki of 8.5 μM.
• High purity suitable for research (≈98.1%).
• Molecular weight 321.37 g/mol; formula C20H19NO3.
• Suitable for in vitro biochemical and cell-based assays.
• Storage under nitrogen recommended; refrigerated at 4°C; in solvent: -80°C (6 months) or -20°C (1 month).
• Supplied as a small quantity research sample for laboratory use.

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Medchemexpress LLC CDC25B-IN-1 | 2374831-10-2 | 98.1% | 321.37 g/mol | C20H19NO3 | 50MG

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CDC25B-IN-1 is a small-molecule research inhibitor of the cell division cycle 25B (CDC25B) phosphatase. It has a reported Ki of approximately 8.5 μM, reduces cell proliferation and colony formation, and increases the proportion of cells in the G2/M phase. The compound is supplied at high reported purity and is available in multiple pack sizes, including mg quantities and as a DMSO solution suitable for biochemical and cell-based assays.

• Potent inhibitor of CDC25B phosphatase with reported Ki ≈ 8.5 μM.
• Inhibits cell proliferation and colony formation in cellular assays.
• Causes accumulation of cells in the G2/M phase.
• Supplied with high reported purity for research use.
• Available in multiple pack sizes and as a DMSO solution for convenience.

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Medchemexpress LLC 2-phenylaminoadenosine | 53296-10-9 | MFCD00055119 | 98.0% | 358.35 g/mol | C16H18N6O4 | 5 MG

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CV1808 (2-phenylaminoadenosine) is a research-grade, non-selective A2 adenosine receptor agonist used in pharmacology and receptor-binding studies. It shows reported Ki values of 76 nM at the A2A receptor and 1,450 nM at the A3 receptor, has molecular formula C16H18N6O4 and molecular weight 358.35 g/mol, and is supplied as a solid with analytical purity around 98.0% for research use only.

• Non-selective A2 adenosine receptor agonist
• Reported Ki: A2A = 76 nM; A3 = 1,450 nM
• Molecular formula C16H18N6O4; molecular weight 358.35 g/mol
• Analytical purity approximately 98.0%
• Supplied as a solid for laboratory research applications

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eMolecules​ Ambeed / Borate(1-) trifluoro(2-fluoro-6-hydroxyphenyl)- potassium (11) / 1g / 660580557 / A1147041 / / 2252415-10-2 / [null] / 218.000 / C6H4BF4KO

Ambeed / Borate(1-) trifluoro(2-fluoro-6-hydroxyphenyl)- potassium (11) / 1g / 660580557 / A1147041 / / 2252415-10-2 / [null] / 218.000 / C6H4BF4KO

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STA PHARMACEUTICAL US LLC 3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid | 10 g | CAS 875211-10-2 | InChIKey RXRDRSUDCSEVRK-UHFFFAOYSA-N

3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid is a Amino Acid reagent (Subcategory: Alkane AA) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.

Specifications
- CAS: 875211-10-2
- MDL: No data
- InChIKey: RXRDRSUDCSEVRK-UHFFFAOYSA-N
- Molecular Weight: 417.505
- Molecular Formula: C26H27NO4
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)adamantane-1-carboxylic acid
- SMILES: OC(C12CC3CC(C2)CC(C1)(NC(OCC4C5=CC=CC=C5C6=CC=CC=C46)=O)C3)=O

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Medchemexpress LLC 4-(5-fluoro-1H-benzo[d]imidazol-2-yl)-N,N-dimethylaniline | 1458664-10-2 | MFCD20720876 | 99.6% | 255.29 | C15H14FN3 | 5 MG

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β-catenin-IN-2 (Compound H1B1) is a small-molecule β-catenin inhibitor for research use, reported as a pink to red solid with high purity. It is characterized by molecular formula C15H14FN3 and a molecular weight of 255.29 g/mol, and is used in studies of colorectal cancer and β-catenin pathway biology.

• Potent β-catenin inhibitor for colorectal cancer research.
• Molecular formula C15H14FN3.
• Molecular weight 255.29 g/mol.
• Appearance: pink to red solid.
• Purity around 99.6% by HPLC.
• Available in small milligram-scale packages for laboratory studies.
• Typically prepared and handled in solution (DMSO) for assays.

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Medchemexpress LLC Ethyl 3-[(3-methoxynaphthalen-1-yl)amino]benzoate | 2374831-10-2 | 98.1% | 321.37 | C20H19NO3 | 100MG

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CDC25B-IN-1 is a small-molecule inhibitor of the CDC25B phosphatase used for biochemical and cellular research. Reported as compound 4a, it inhibits CDC25B with a Ki of 8.5 μM, reduces cell proliferation and colony formation, and induces G2/M cell-cycle arrest. The material is typically supplied as a light brown oil or as a DMSO solution for assay use.

• Inhibits CDC25B with a reported Ki of 8.5 μM.
• Reduces cell proliferation and colony formation in cellular assays.
• Induces G2/M cell-cycle arrest.
• Molecular formula C20H19NO3; molecular weight 321.37.
• High purity (approximately 98.1%; may vary by batch).
• Available in multiple quantities and solution formats for assay convenience.
• Storage recommendations include refrigeration under inert atmosphere and low-temperature storage in solvent.

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