Alcohols and polyols
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- (1)
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- (1)
- (462)
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- (1)
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- (145)
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- (1)
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- (2)
- (2)
- (2)
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- (1)
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- (7)
- (3)
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- (1)
- (36)
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- (2)
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- (33)
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- (7)
- (2)
- (1)
- (26)
- (1)
- (1)
- (1)
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- (1)
- (3)
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- (3)
- (1)
- (15)
- (12)
- (1)
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- (12)
- (1)
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- (24)
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- (1)
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- (1)
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- (1)
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- (1)
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- (1)
- (1)
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- (81)
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- (378)
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Filtered Search Results
Medchemexpress LLC Nimustine hydrochloride | 55661-38-6 | MFCD01676942 | 98.2% | C9H14Cl2N6O2 | 10MG
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Nimustine hydrochloride is the hydrochloride salt of nimustine, an alkylating antitumor agent used in research to induce DNA damage and study DNA-damage response pathways. It produces DNA double-strand breaks and inter-strand crosslinks and activates signaling cascades involved in the DNA damage response.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Ly 303511 hydrochloride | 2070014-90-1 | 98.9% | 342.82 g·mol⁻¹ | C19H19ClN2O2 | 10 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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LY 303511 hydrochloride is a research-grade small molecule (CAS 2070014-90-1) that acts as a structural analogue of LY294002; it enhances TRAIL sensitivity in SHEP-1 neuroblastoma cells and reversibly blocks potassium currents in MIN6 insulinoma cells. Supplied as a 10 mg solid with high purity for in vitro studies. Store sealed and protected from moisture.
- High purity (98.9%) suitable for screening and biochemical assays.
- Compact 10 mg pack for dose-response and early-stage experiments.
- Solid form stable under recommended storage temperatures when sealed.
- Documented activity on TRAIL sensitivity and potassium current modulation.
- CAS number provided for precise chemical identification.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Tenapanor hydrochloride | 1234365-97-9 | MFCD31631378 | 99.6% | 1217.97 | C50H68Cl6N8O10S2 | 10 MG
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Tenapanor hydrochloride is a potent, orally active sodium/hydrogen exchanger 3 (NHE3) inhibitor supplied for research use. It is provided as a white to off-white solid and is available in solid and solution formats for in vitro and in vivo studies.
- Potent NHE3 inhibitor for pharmacology and preclinical research.
- Provided as a white to off-white solid and as solution formulations.
- Reported purity 99.6% with analytical data (COA, HPLC, LCMS) available.
- Soluble in DMSO and water; formulation protocols give clear solutions ≥ 5 mg/mL.
- Recommended storage: 4°C sealed, away from moisture and light; in solvent store at -80°C for long-term.
- For research use only; not for human use or sale to patients.
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Medchemexpress LLC Agn 192403 hydrochloride | 1021868-90-5 | 99.0% | 189.73 g/mol | C10H20ClN | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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AGN 192403 hydrochloride is the hydrochloride salt of a selective I1-imidazoline receptor antagonist used in cardiovascular and neurological research. It is supplied in small research quantities with high reported purity, and includes solubility and formulation guidance for in vitro and in vivo studies.
- Selective I1-imidazoline receptor antagonist for receptor pharmacology studies.
- Hydrochloride salt form improves solubility in polar solvents.
- High purity suitable for biochemical and cellular assays.
- Available in small milligram quantities for preclinical research.
- Soluble in DMSO; in vivo formulation recipes and concentrations are reported.
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Medchemexpress LLC Nordoxepin hydrochloride | 2887-91-4 | 99.9% | 301.81 g/mol | C18H20ClNO | 10 MG
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Nordoxepin hydrochloride is the primary metabolite of the tricyclic antidepressant doxepin and is provided as a solid research reagent for analytical, pharmacological, and metabolic studies. It is supplied with characterized purity and storage recommendations and is intended for research use only (not for human or veterinary use).
- Chemical identity: CAS 2887-91-4; formula C18H20ClNO; MW 301.81 g/mol.
- High purity (99.94%).
- Appearance: solid; store sealed and away from moisture.
- Storage in solvent: -80°C up to 6 months; -20°C up to 1 month.
- Intended applications: analytical and pharmacokinetic research.
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Medchemexpress LLC Bevantolol hydrochloride | 42864-78-8 | 10 MG
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Bevantolol hydrochloride is a beta-1 and alpha-1 adrenergic receptor antagonist supplied as an analytical standard for laboratory research in adrenergic pharmacology.
- Selective β1 and α1 adrenergic receptor antagonist.
- Supplied as an analytical standard for research use.
- CAS number 42864-78-8.
- Molecular formula C20H28ClNO4; molecular weight 381.89 g/mol.
- Available in small milligram pack sizes, including 10 MG for analytical applications.
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Medchemexpress LLC Clemizole hydrochloride | 1163-36-6 | 99.99% | 362.30 | 100 MG
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Clemizole hydrochloride is an H1 histamine receptor antagonist that substantially inhibits HCV replication and is an inhibitor of the TRPC5 channel. It has an IC50 of 24 nM for RNA binding by NS4B and an EC50 of 8 μM for viral replication. For research use only.
- H1 histamine receptor antagonist.
- Substantially inhibits HCV replication.
- Inhibitor of TRPC5 channel.
- EC50 of 8 μM for viral replication.
- IC50 of 24 nM for RNA binding by NS4B.
- Inhibits HCV RNA replication in cell culture mediated by suppression of NS4B's RNA binding with little toxicity for the host cell.
- Efficiently blocks TRPC5 currents and Ca2+ entry in the low micromolar range (IC50=1.0-1.3 μM).
- Exhibits six-fold selectivity for TRPC5 over TRPC4β (IC50=6.4 μM) and almost 10-fold selectivity over TRPC3 (IC50=9.1 μM) and TRPC6 (IC50=11.3 μM).
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Medchemexpress LLC Midodrine (hydrochloride) | 43218-56-0 | 99.9% | 1 ML
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Midodrine hydrochloride is a selective and orally active adrenergic α1-receptor agonist that strengthens vascular contraction. It is used for research on cardiovascular diseases, including orthostatic hypotension.
- Selective and orally active adrenergic α1-receptor agonist
- Strengthens vascular contraction
- Used for research on cardiovascular diseases and orthostatic hypotension
- Increases p-AMPK and PPARδ expression in C2C12, HL1, and HepG2 cells
- Increases Ca2+ and ATP content in C2C12, HL1, and HepG2 cells
- Reduces cellular lipid content in 3T3-L1 cells
- Reduces platelet-activating factor (Paf)-induced death in mice
- Demonstrates anti-hypotensive effects in orthostatic hypotension rat models
- Relieves hypertension in spontaneously hypertensive rat models
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Medchemexpress LLC VU0453379 hydrochloride | 99.0% | 471.03 | 1 ML
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VU0453379 hydrochloride is a highly selective and central nervous system (CNS) penetrant positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R). It exhibits an EC50 of 1.3 μM.
- Highly selective positive allosteric modulator.
- Central nervous system (CNS) penetrant.
- Modulates glucagon-like peptide-1R (GLP-1R).
- Demonstrates an EC50 of 1.3 μM.
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Medchemexpress LLC Alosetron hydrochloride | 122852-69-1 | MFCD03453647 | 99.6% | 10 MG
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Alosetron hydrochloride is a potent, selective 5-HT3 receptor antagonist provided for research use in studies of irritable bowel syndrome and visceral nociception. It is supplied as a high-purity solid and is also available as ready-to-use 10 mM solutions for laboratory assays.
- Potent and selective 5-HT3 receptor antagonist.
- Used in research on diarrhea-predominant irritable bowel syndrome and visceral nociception.
- High purity suitable for analytical and in vitro applications.
- Available as a solid and as pre-made 10 mM solutions for convenience.
- Characterization includes CAS 122852-69-1 and molecular weight 330.81 g/mol.
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Medchemexpress LLC Benzoic acid, 2-[4-[2-(1-piperidinyl)ethoxy]benzoyl]-, methyl ester, hydrochloride (1:1) | 1248-42-6 | 99.9% | 403.90 | 25 MG
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Pitofenone hydrochloride is a spasmolytic compound that inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and electric eel with Kis of 36 and 45 μM, respectively. It also exhibits anticonvulsant activity when combined with diclofenac and fenpivirine.
- Spasmolytic compound
- Inhibits acetylcholinesterase (AChE) activity
- Anticonvulsant activity in combination with diclofenac and fenpivirine
- Appearance: Solid
- Color: White to off-white
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Medchemexpress LLC Drofenine hydrochloride | 548-66-3 | 98.1% | 1 ML
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Drofenine hydrochloride is a potent competitive cholinesterase inhibitor. It acts as a BChE inhibitor with a Ki value of 3 μM and is intended for research use only.
- Potent competitive cholinesterase inhibitor
- BChE inhibitor
- Ki value of 3 μM
- Suitable for research use
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Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 | C24H34ClN5O4S | 5MG
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Yonkenafil hydrochloride is the hydrochloride salt of a selective phosphodiesterase 5 (PDE5) inhibitor supplied for research use. It is provided as a high-purity solid suitable for in vitro and preclinical studies involving PDE5-related pathways, neuroscience, and pharmacology. Typical solvent compatibility includes DMSO; follow the SDS and laboratory safety procedures.
- High purity suitable for research.
- Solid form for accurate weighing and formulation.
- Soluble in DMSO for assay preparation.
- Appropriate for in vitro and preclinical pharmacology studies.
- Available in small-scale vials for dose-ranging experiments.
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Medchemexpress LLC Nimustine hydrochloride (ACNU) | 55661-38-6 | 98.2% | 309.15 | 1 ML
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Nimustine hydrochloride (ACNU) is the hydrochloride salt form of Nimustine. It functions as an alkylating agent by inducing DNA double-strand breaks (DSBs) and inter-strand crosslinks (ICLs), which activates the DNA damage response (DDR) signaling pathway. It also activates the p38 MAPK/JNK signaling pathway and demonstrates antitumor activity.
- Induces DNA double-strand breaks and inter-strand crosslinks.
- Activates DNA damage response signaling.
- Activates p38 MAPK/JNK signaling.
- Demonstrates antitumor activity.
- Exhibits cytotoxicity against human U87MG cells.
- Induces apoptosis in LN-229 cells.
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Medchemexpress LLC SRI-37330 hydrochloride | 2322245-49-6 | 99.7% | C16H20ClF3N4O2S | 25 MG
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SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. It inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis. This compound can be used for type 2 diabetes research.
- Inhibits activity of human TXNIP promoter in INS-1 cells.
- Decreases mRNA and protein levels of TXNIP in INS-1 cells.
- Inhibits polymerase II (Pol II) binding to the E-box motif region of the TXNIP promoter.
- Lowers glucagon secretion in TC1-6 cells.
- Inhibits glucagon-induced glucose output from primary hepatocytes.
- Decreases glucagon secretion and action in mice.
- Blocks hepatic glucose output in mice.
- Reverses obesity- and streptozotocin-induced diabetes and hepatic steatosis in mice.
- Well tolerated in male C57BL/6J mice.
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