Sulfoxides
Medchemexpress LLC NR2F6 modulator-1 | 904449-84-9 | 99.46% | 419.45 | 1 ML
NR2F6 modulator-1 is a potent nuclear receptor subfamily 2, group F, member 6 (NR2F6) modulator. It is utilized for research concerning immune modulation and the modulation of cancer stem cell activity.
- Potent nuclear receptor subfamily 2, group F, member 6 (NR2F6) modulator
- Utilized for researching immune modulation
- Utilized for modulation of cancer stem cell activity
- Appears as a solid
- Color ranges from off-white to light yellow
- Soluble in DMSO at 125 mg/mL
Medchemexpress LLC Ritonavir metabolite (Desthiazolylmethyloxycarbonyl Ritonavir) | 176655-55-3 | 99.6% | 579.80 | 5 MG
Ritonavir metabolite is a metabolite of Ritonavir, which is an HIV protease inhibitor. The product appears as a white to off-white solid.
- Purity of 99.6%
- Molecular weight of 579.80
- CAS number 176655-55-3
- Storage at -20°C for powder, -80°C for 6 months in solvent
- Shipping at room temperature in continental US
Medchemexpress LLC GLP-1R modulator C16 | 875005-43-9 | 99.6% | 408.89 g·mol⁻1 | C21H26ClFN2O3 | 5 MG
GLP-1R modulator C16 is a small-molecule allosteric modulator that enhances GLP-1 binding to the GLP-1 receptor via a transmembrane site (CAS 875005-43-9). It is characterized in vitro with an EC50 of 8.43 ± 3.82 μM, a molecular weight of 408.89 g·mol⁻1, and high chemical purity suitable for research applications.
- Allosteric modulator of GLP-1 receptor activity.
- Characterized potency (EC50 8.43 ± 3.82 μM) for in vitro studies.
- High chemical purity (99.6%) for reproducible results.
- Compact quantities suitable for early-stage pharmacology.
- Useful for studying GLP-1R pharmacology and GPCR signaling.
Cayman Chemical Sulforaphane Inhibitors
An isothiocyanate that potently induces chemopreventative enzymes via Keap1-Nrf2 signaling and ARE-driven gene expression; at 15 μM, inhibits class I and II HDAC activity and suppresses tumor growth selectively in cancerous prostate epithelial cells without affecting normal cells
Medchemexpress LLC Sodium decane-1-sulfonate | 13419-61-9 | 244.33 | 100 MG
Sodium decane-1-sulfonate, also known as 1-Decanesulfonic acid sodium, is an anionic surfactant primarily utilized in analytical chemistry. Its main application lies in the analysis of organic small molecule compounds through High-Performance Liquid Chromatography (HPLC) and ion-pair liquid chromatography. This biochemical assay reagent is a solid with a molecular weight of 244.33 and the chemical formula C10H21NaO3S. It is intended for research use only.
- Anionic surfactant
- Used for analysis of organic small molecule compounds
- Applications in HPLC and ion-pair liquid chromatography
- Solid form
- Molecular weight: 244.33
- Formula: C10H21NaO3S
- CAS No.: 13419-61-9
- Recommended storage at 4°C, sealed, away from moisture; in solvent: -80°C for 6 months or -20°C for 1 month
- For research use only
Medchemexpress LLC CB2R/FAAH modulator-3 | 2876918-67-9 | C22H31NO2 | 1 ML
CB2R/FAAH modulator-3 is a dual-targeting modulator that functions as a Cannabinoid receptor 2 (CB2R) agonist and a Fatty Acid Amide Hydrolase (FAAH) inhibitor. This modulator demonstrates a high affinity for CB2R with a Ki value of 20.1 nM, and a lower affinity for CB1R with a Ki value of 67.6 nM. It inhibits FAAH with an IC50 value of 3.4 μM. In in vitro studies, at a concentration of 10 μM, it has been shown to reduce the production of pro-inflammatory cytokines, including TNFα, IFN-γ, IL-1β, and IL6, in unstimulated monocytes and macrophages.
- Suitable for use in research related to various conditions, such as cancer.
- Suitable for use in research related to inflammatory cascades associated with neurodegenerative diseases.
- Suitable for use in research related to COVID-19 infection.
Cayman Chemical SulIndac sulfon 25mg
An oxidized metabolite of sulindac that is produced in many mammals but minimally in mice and rats; generally considered to be inactive against COX enzymes, although it can reduce azoxymethane-induced colon cancer in rats; inhibits aldose reductase (IC50 = 367 nM) in vitro
Medchemexpress LLC (+)-LRH-1 modulator-1 | 2244781-29-9 | 99.38% | 464.66 | 50 MG
(+)-LRH-1 modulator-1 is a stereoisomer of LRH-1 modulator-1, a potent LRH-1 (liver receptor homolog-1) modulator/agonist. It exhibits anti-inflammatory effects in intestinal organoids by inducing the anti-inflammatory cytokine IL-10 and reducing the inflammatory cytokines IL-1b and TNFa.
- Potent LRH-1 modulator/agonist
- Exhibits anti-inflammatory effects in intestinal organoids
- Induces anti-inflammatory cytokine IL-10
- Reduces inflammatory cytokines IL-1b and TNFa
- Pure form storage: -20°C for 3 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Shipping conditions: Room temperature if less than 2 weeks
Alkali Scientific Novobiocin Sodium Salt, 100 Grams
Novobiocin Sodium Salt is an antibiotic used to inhibit bacterial growth, especially for the isolation of Gram-positive bacteria. This 100g powder formulation is a valuable tool for laboratory research, where it is primarily used to study bacterial resistance mechanisms and to control bacterial contamination in culture media. Novobiocin inhibits DNA gyrase, an essential enzyme in bacterial replication, making it effective for selective bacterial inhibition. Laboratories use this antibiotic for a variety of microbial assays, including testing bacterial susceptibility and studying the biochemical properties of different bacterial strains.
eMolecules Medchem Express / (R)-Sulforaphane / 5mg / 599150753 / HY-13755A / / 142825-10-3 / MFCD09039283 / 177.280 / C6H11NOS2
Medchem Express / (R)-Sulforaphane / 5mg / 599150753 / HY-13755A / / 142825-10-3 / MFCD09039283 / 177.280 / C6H11NOS2