Coumarins and derivatives
Indofine Chemical QUERCETIN anhydrous, Flavonoid & Coumarins, 117-39-5, 1 gm
QUERCETIN anhydrous, Flavonoid & Coumarins, 117-39-5, 1 gm
Medchemexpress LLC 3-Hydroxycoumarin | 939-19-5 | 99.3% | 50 MG
3-Hydroxycoumarin is an inhibitor of tyrosinase and lipoxygenase (LOX), with an IC50 for recombinant human tyrosinase (rHT) of 26 μM and an IC50 for LOX of 9.5 μM. It exhibits DPPH free radical scavenging activity and has photoprotective effects on sea urchin zygotes and embryos. The compound has also demonstrated anticancer activity against human SK-MEL-28 cells and SK-MEL3 cells in vitro.
- Inhibits tyrosinase and lipoxygenase
- Exhibits DPPH free radical scavenging activity
- Provides photoprotective effects on sea urchin zygotes and embryos
- Shows anticancer activity against human SK-MEL-28 and SK-MEL3 cells
- Can be formulated into a vesicle delivery system for topical administration
Medchemexpress LLC 7-Hydroxycoumarin-4-acetic acid | 6950-82-9 | 250 MG
7-Hydroxycoumarin-4-acetic acid is a pH-indicator dye that is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λmax=326 nm). This product is intended for research use only.
- pH-indicator dye
- Covalently bound to bovine serum albumin (BSA)
- White to off-white solid
- Molecular weight 220.18
- Chemical formula C11H8O5
- Emission (Em): 450
- Excitation (Ex): 415
- Store at 4°C, protect from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protect from light
Medchemexpress LLC 4-Hydroxycoumarin (standard) | 1076-38-6 | 50 MG
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin, intended for research and analytical applications. It is an orally active coumarin derivative and a versatile heterocyclic scaffold, frequently used in the synthesis of diverse organic compounds. The product exhibits both electrophilic and nucleophilic properties.
- Analytical standard.
- Intended for research and analytical applications.
- Orally active coumarin derivative.
- Versatile heterocyclic scaffold.
- Used in the synthesis of various organic compounds.
- Possesses both electrophilic and nucleophilic properties.
- Functions as an HIV protease inhibitor.
- Functions as a tyrosine kinase inhibitor.
- Displays anti-inflammatory effects.
- Displays antibacterial effects.
- Displays anti-tumor effects.
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | 25 G
4-Hydroxycoumarin is an orally active coumarin derivative, and a versatile heterocyclic scaffold often used in the synthesis of various organic compounds. It possesses both electrophilic and nucleophilic properties, acting as an HIV protease inhibitor and a tyrosine kinase inhibitor. This compound also demonstrates anti-inflammatory, antibacterial, and anti-tumor effects.
- Versatile heterocyclic scaffold for organic synthesis.
- Exhibits electrophilic and nucleophilic properties.
- Acts as an HIV protease inhibitor.
- Functions as a tyrosine kinase inhibitor.
- Possesses anti-inflammatory effects.
- Demonstrates antibacterial activity.
- Shows anti-tumor effects.
- Relevant in infection research.
- Relevant in cancer research.
- High purity (99.26% by HPLC).
Medchemexpress LLC 7-hydroxycoumarin-3-carboxylic acid N-succinimidyl ester | 134471-24-2 | 100 MG
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. It functions as a blue fluorescent dye for labeling proteins and nucleic acids.
- Amine-reactive succinimidyl ester
- Blue fluorescent dye
- Used for labeling proteins
- Used for labeling nucleic acids
Indofine Chemical 7-Hydroxycoumarin, 99%, 5 Gm
7-HYDROXYCOUMARIN 5 GM, Coumarin, Umbelliferone, C9H6O3, MW: 162.14, 99+%, 93-35-6, MFCD00006878
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | 50 G
4-Hydroxycoumarin is an orally active coumarin derivative, a versatile heterocyclic scaffold used in synthesizing various organic compounds. It possesses both electrophilic and nucleophilic properties. It acts as an HIV protease inhibitor and tyrosine kinase inhibitor, and exhibits anti-inflammatory, antibacterial, and anti-tumor effects.
- Orally active coumarin derivative
- Versatile heterocyclic scaffold for organic compound synthesis
- Possesses both electrophilic and nucleophilic properties
- Acts as an HIV protease inhibitor
- Acts as a tyrosine kinase inhibitor
- Exhibits anti-inflammatory effects
- Exhibits antibacterial effects
- Exhibits anti-tumor effects
Medchemexpress LLC Esculetin | 305-01-1 | 99.79% | 178.14 | 1 ML
Esculetin is an active ingredient extracted mainly from the bark of *Fraxinus rhynchophylla*. It primarily functions by inhibiting the PI3K/Akt pathway, which affects platelet-derived growth factor (PDGF)-induced airway smooth muscle cells (ASMCs) phenotype switching. Additionally, Esculetin demonstrates antioxidant, anti-inflammatory, and antitumor properties, making it a subject of various research applications. It is intended for research use only and not for medical or patient use.
- Inhibits platelet-derived growth factor (PDGF)-induced airway smooth muscle cell (ASMC) proliferation and migration.
- Demonstrates antioxidant activity.
- Exhibits anti-inflammatory effects.
- Possesses antitumor activities.
- Targets PI3K pathway.
- Induces apoptosis in certain cancer cell types.
- Ameliorates skin lesions in psoriatic mice models.
Medchemexpress LLC Palomid 529 | 914913-88-5 | 99.4% | C24H22O6 | 1 ML
The product is a potent inhibitor of both mTORC1 and mTORC2 complexes, affecting the PI3K/AKT/mTOR pathway. It demonstrates the ability to reduce endothelial cell proliferation and induce apoptosis in vitro, as well as exhibit antitumor activity in various cancer cell lines and mouse models. This compound interferes with the pathway through the dissociation of mTOR complex 1 and mTOR complex 2, leading to decreased phosphorylation of substrates, cell growth inhibition, and cell death.
- Potent inhibitor of mTORC1 and mTORC2 complexes.
- Inhibits VEGF-driven and bFGF-driven endothelial cell proliferation.
- Induces endothelial cell apoptosis.
- Reduces Akt activity in various cancer cell lines.
- Demonstrates antitumor activity in glioblastoma, prostate, and breast cancer models.
- Causes cell growth inhibition and death in cancer cells.
Indofine Chemical Linarin With Hplc, 5 Mg
LINARIN with HPLC, Flavonoid & Coumarins, 480-36-4, 98.5% by HPLC, 5 mg
Medchemexpress LLC 3-(1H-benzimidazol-2-yl)-7-(diethylamino)chromen-2-one | 27425-55-4 | MFCD00051348 | 99.8% | 333.38 g/mol | C20H19N3O2 | 100MG
Coumarin 7 (CAS 27425-55-4) is a coumarin-class laser dye and fluorescent research reagent used in spectroscopy and laser applications. It has molecular formula C20H19N3O2, a molecular weight of 333.38 g/mol, and is supplied with a reported purity of 99.80% for laboratory use.
- High reported purity: 99.8%.
- Suitable for spectroscopy, fluorescence, and laser dye studies.
- Molecular formula C20H19N3O2 and molecular weight 333.38 g/mol.
- Available in small research quantities, including 50 mg and 100 mg.
- Intended for research use in laboratory applications.
Apexbio Technology LLC Coumarin 6 38215-36-0 10mg
Coumarin 6 (CAS 38215-36-0) is a fluorescent dye utilized primarily as a tracer in biomedical research for particulate drug delivery systems Coumarin 6 facilitates the visualization and analysis of particle distribution trafficking and cellular uptake processes in vitro and in vivo It is applied to study biological mechanisms related to transport and localization of therapeutic molecules and their interactions with cellular compartments Based on these properties Coumarin 6 holds research potential in evaluating drug delivery dynamics cellular internalization pathways pharmacokinetic behavior and disease-related investigations