Coumarins and derivatives
Sigma Aldrich Fine Chemicals Biosciences Scopoletin >=99% | 92-61-5 | MFCD00006872 | 500MG
Scopoletin >=99% | Purity: >=99% | Mol Wt: 192.17 | 92-61-5 | MFCD00006872 | 500MG
Sigma Aldrich Fine Chemicals Biosciences Scopoletin >=99% | 92-61-5 | MFCD00006872 | 50MG
Scopoletin >=99% | Purity: >=99% | Mol Wt: 192.17 | 92-61-5 | MFCD00006872 | 50MG
Sigma Aldrich Fine Chemicals Biosciences Esculin hydrate >=98.0% (HPLC) | 531-75-9 (anhydrous) | MFCD00149492 | 10G
Esculin hydrate >=98.0% (HPLC) | Purity: >=98.0% (HPLC) | 531-75-9 (anhydrous) | MFCD00149492 | 10G
Medchemexpress LLC (2,5-dioxopyrrolidin-1-yl) 7-hydroxy-2-oxochromene-3-carboxylate | 134471-24-2 | MFCD00037568 | >96.0% | 303.22 g/mol | C14H9NO7 | 10 MG
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is an N-hydroxysuccinimide (NHS)-activated fluorescent labeling reagent that introduces a 7-hydroxycoumarin fluorophore onto primary amines. Provided as a solid for research use, it is intended for bioconjugation and fluorescence-based assays.
- Reacts with primary amines via NHS ester chemistry for covalent labeling.
- Provides a blue/UV-excitable coumarin fluorophore suitable for protein, peptide, and nucleic acid labeling.
- Available in small-scale quantities convenient for analytical and preparative labeling.
- High chemical purity suitable for coupling reactions (suppliers report >96%).
- Stable when stored as directed; consult the product datasheet or certificate of analysis for storage and handling details.
Chem-Impex International, Inc. 7-Hydroxy-4-methylcoumarin | 90-33-5 | MFCD00006866 | 25G
7-Hydroxy-4-methylcoumarin, 90-33-5, MFCD00006866, 25G
Medchemexpress LLC 3-aminocoumarin (3-aminochromen-2-one) | 1635-31-0 | MFCD00016965 | 161.16 g/mol | C9H7NO2 | 1 G
3-Aminocoumarin (3-aminochromen-2-one) is an organic intermediate commonly used in coordination chemistry and organic synthesis as a precursor to ligands and metal complexes. Supplied for research use, it is intended for preparative and exploratory synthesis workflows where a well-characterized coumarin derivative is required.
- Serves as an intermediate for synthesis of metal complexes and ligands.
- Suitable for coordination chemistry and related organic synthesis applications.
- Characterized small molecule: formula C9H7NO2, molecular weight 161.16 g/mol.
- Recommended storage: 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month).
- Intended for research use only.
Cayman Chemical 7-ethoxy-4-MethylcoumarIn 1g
A fluorophore used to monitor functional activity of CYP1A1, CYP2B4, and CYP2B6; excitation/emission maxima equals 318 and 377 nm, respectively in methanol and 360 and 449 nm, respectively in dealkylase
Medchemexpress LLC 7-Methylcoumarin | 2445-83-2 | MFCD00006880 | 5 G
7-Methylcoumarin is a coumarin derivative known for its potent hepatoprotective and antioxidant properties. It functions as a mechanism-based inhibitor for CYP2A6, a key enzyme involved in drug metabolism. Studies have shown that it can significantly reduce markers of liver damage, such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB), in models of CCl4-induced liver injury. Additionally, it helps to restore total protein (TP) and albumin (TA) levels and prevent oxidative stress. It also exhibits an ability to decrease the mitotic activity of *A. sativum* promeristem.
- Possesses potent hepatoprotective properties
- Acts as a mechanism-based inhibitor for CYP2A6
- Reduces markers of liver damage
- Restores protein and albumin levels in serum
- Prevents oxidative stress
- Decreases mitotic activity
Selleck Chemical LLC Dicoumarol-50mg
Dicoumarol is a competitive NADPH quinone oxidoreductase (NQO1) inhibitor,and used as an anticoagulant by interfering with the metabolism of vitamin K.
Cayman Chemical 4-HydroxycoumarIn 100g
A coumarin; inhibits vitamin K1 epoxidation and prothrombin synthesis by 18 and 67%, respectively, in cell-free assays at 6.2 mM; has been used in the synthesis of anticoagulants, as well as antithrombotic, anti-inflammatory, antibacterial, and antifungal agents
Indofine Chemical KAEMPFEROL-7-O-NEOHESPERIDOSIDE, Flavonoid & Coumarins, 17353-03-6, >95% by HPLC, 10 mg
KAEMPFEROL-7-O-NEOHESPERIDOSIDE, Flavonoid & Coumarins, 17353-03-6, >95% by HPLC, 10 mg
Medchemexpress LLC 6-Hydroxycoumarin | 6093-68-1 | 10 G
6-Hydroxycoumarin is a coumarin exhibiting diverse biological activities. It is noted for its anti-inflammatory, anti-pyretic, anti-oxidant, and vasodilator properties. This compound also demonstrates anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic, and antitumor activities.
- Demonstrates anti-inflammatory, anti-pyretic, and anti-oxidant activities
- Acts as a vasodilator, anti-amoebic, anti-bacterial, and anti-fungal agent
- Exhibits bacteriostatic and antitumor properties
- Appearance: light yellow to light brown solid
- Molecular formula: C9H6O3
- Molecular weight: 162.14
- Purity: 99.32%
- Melting point: 249-253 °C
- Boiling point: 248.82 °C at 760 mmHg
Medchemexpress LLC 3-Hydroxycoumarin | 939-19-5 | 99.3% | 50 MG
3-Hydroxycoumarin is an inhibitor of tyrosinase and lipoxygenase (LOX), with an IC50 for recombinant human tyrosinase (rHT) of 26 μM and an IC50 for LOX of 9.5 μM. It exhibits DPPH free radical scavenging activity and has photoprotective effects on sea urchin zygotes and embryos. The compound has also demonstrated anticancer activity against human SK-MEL-28 cells and SK-MEL3 cells in vitro.
- Inhibits tyrosinase and lipoxygenase
- Exhibits DPPH free radical scavenging activity
- Provides photoprotective effects on sea urchin zygotes and embryos
- Shows anticancer activity against human SK-MEL-28 and SK-MEL3 cells
- Can be formulated into a vesicle delivery system for topical administration
Medchemexpress LLC 7-Hydroxycoumarin-4-acetic acid | 6950-82-9 | 250 MG
7-Hydroxycoumarin-4-acetic acid is a pH-indicator dye that is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λmax=326 nm). This product is intended for research use only.
- pH-indicator dye
- Covalently bound to bovine serum albumin (BSA)
- White to off-white solid
- Molecular weight 220.18
- Chemical formula C11H8O5
- Emission (Em): 450
- Excitation (Ex): 415
- Store at 4°C, protect from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protect from light
Medchemexpress LLC 4-Hydroxycoumarin (standard) | 1076-38-6 | 50 MG
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin, intended for research and analytical applications. It is an orally active coumarin derivative and a versatile heterocyclic scaffold, frequently used in the synthesis of diverse organic compounds. The product exhibits both electrophilic and nucleophilic properties.
- Analytical standard.
- Intended for research and analytical applications.
- Orally active coumarin derivative.
- Versatile heterocyclic scaffold.
- Used in the synthesis of various organic compounds.
- Possesses both electrophilic and nucleophilic properties.
- Functions as an HIV protease inhibitor.
- Functions as a tyrosine kinase inhibitor.
- Displays anti-inflammatory effects.
- Displays antibacterial effects.
- Displays anti-tumor effects.