Coumarins and derivatives
Cayman Chemical 7-AmIno-4-methylcoumarIn 500mg
A fluorescent probe for peptide labeling commonly used in the study of proteases; conjugation via its amino group to a peptide substrate results in quenching of the fluorescent signal; upon enzymatic cleavage of the peptide by proteases, AMC is released and its fluorescence can be used to quantify enzyme activity; ex/em = 345/445 nm, respectively
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | 25 G
4-Hydroxycoumarin is an orally active coumarin derivative, and a versatile heterocyclic scaffold often used in the synthesis of various organic compounds. It possesses both electrophilic and nucleophilic properties, acting as an HIV protease inhibitor and a tyrosine kinase inhibitor. This compound also demonstrates anti-inflammatory, antibacterial, and anti-tumor effects.
- Versatile heterocyclic scaffold for organic synthesis.
- Exhibits electrophilic and nucleophilic properties.
- Acts as an HIV protease inhibitor.
- Functions as a tyrosine kinase inhibitor.
- Possesses anti-inflammatory effects.
- Demonstrates antibacterial activity.
- Shows anti-tumor effects.
- Relevant in infection research.
- Relevant in cancer research.
- High purity (99.26% by HPLC).
Medchemexpress LLC HY-D0055 10mg Medchemexpress, 3-Cyano-7-ethoxycoumarin CAS:117620-77-6 Purity:>98%
Medchemexpress, HY-D0055 10mg 3-Cyano-7-ethoxycoumarin CAS:117620-77-6 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC HX 531 188844-34-0 5mg
HX 531 (CAS 188844-34-0) is a small-molecule antagonist targeting the retinoid X receptor (RXR) It modulates RXR-associated signaling pathways thereby influencing both tumorigenic and metabolic biological processes HX 531 exerts its biological activity by antagonizing RXR which results in cell cycle arrest at the G0/G1 phase and modulation of leptin-dependent pathways and the p53-p21Cip1 signaling axis In rodent models HX 531 demonstrates an inhibitory activity with an IC50 value of approximately 18 nM Based on these pharmacological properties HX 531 holds research potential in the study of metabolic disorders obesity diabetes and cancer biology
Medchemexpress LLC 7-Methoxycoumarin-3-carboxylic acid | 20300-59-8 | MFCD00452770 | 97.0% | 220.18 g/mol | C11H8O5 | 10 G
7-Methoxycoumarin-3-carboxylic acid is a small-molecule fluorescent dye that absorbs in the near-UV (≈345 nm) and emits blue fluorescence (≈450 nm). Supplied as a white to off-white solid, it is used for labeling peptides, HPLC derivatization, and developing FRET-based probes in biochemical assays. It is soluble in DMSO (~8 mg/mL) and typically supplied at 97% purity.
Chem-Impex International, Inc. Esculin hydrate | 531-75-9 | MFCD00149492 | 25G
Esculin hydrate, 531-75-9, MFCD00149492, 25G
AdipoGen Coumarin 102
Chemical. CAS 41267-76-9. Formula C16H17NO2. Molecular Weight 255.31. Coumarin 102 also known as coumarin 480, is a laser dye and is widely used as a dynamic fluorescent probe of both small molecules and host cavities, micelles, polymers and solids. Coumarin 102 belongs to 7-aminocoumarins with a structurally rigidized amino group. Spectral data lambdaex 390nm, lambdaem 466nm in ethanol, lambdalaser 480nm 461-513nm range.
Cayman Chemical 3-HydroxycoumarIn 5g
A coumarin with diverse biological activities; inhibits 15-LO-1 (IC50 = 9.5 µM); scavenges DPPH radicals in a cell-free assay (IC50 = 0.61 mM); inhibits lipid peroxidation in vitro (IC50 = 69.07 mM); protective against UVB-induced embryotoxicity in sea urchins
Medchemexpress LLC Coumarin 480 | 41267-76-9 | MFCD00041844 | 100.0% | 255.31 g/mol | C16H17NO2 | 25 MG
Coumarin 480 (Coumarin 102) is a high-purity fluorescent laser dye used in fluorescence spectroscopy, laser applications, and optical research. It shows strong emission near 480 nm and is supplied as a research-grade reagent for imaging, sensor development, and photophysical studies. Users should follow the product SDS for safe handling and storage.
- High purity (99.95%).
- Strong fluorescence emission near 480 nm.
- Suitable for fluorescence spectroscopy and laser dye applications.
- Useful for sensor development and imaging studies.
- Provided as a research reagent in small vials.
Medchemexpress LLC 3-Hydroxycoumarin | 939-19-5 | 99.3% | 50 MG
3-Hydroxycoumarin is an inhibitor of tyrosinase and lipoxygenase (LOX), with an IC50 for recombinant human tyrosinase (rHT) of 26 μM and an IC50 for LOX of 9.5 μM. It exhibits DPPH free radical scavenging activity and has photoprotective effects on sea urchin zygotes and embryos. The compound has also demonstrated anticancer activity against human SK-MEL-28 cells and SK-MEL3 cells in vitro.
- Inhibits tyrosinase and lipoxygenase
- Exhibits DPPH free radical scavenging activity
- Provides photoprotective effects on sea urchin zygotes and embryos
- Shows anticancer activity against human SK-MEL-28 and SK-MEL3 cells
- Can be formulated into a vesicle delivery system for topical administration