Coumarins and derivatives
Cayman Chemical 7-EthoxycoumarIn 500mg
A CYP450 substrate; undergoes O-deethylation by various CYP isoforms; has been used in the functional characterization of CYPs in cats, rats, and isolated human cornea
Medchemexpress LLC My-1076 | 3008262-76-5 | MFCD35444266 | 99.1% | 539.57 g·mol-1 | C29H33NO9 | 10 MG
MY-1076 is a small-molecule inhibitor of Yes-associated protein (YAP) used for laboratory research. It induces YAP degradation and apoptosis and shows potent antiproliferative activity against several cancer cell lines with low-nanomolar IC50s. Reported properties include CAS 3008262-76-5, formula C29H33NO9, molecular weight 539.57 g·mol-1, and high reported purity.
- Induces YAP degradation and apoptosis in vitro
- Potent antiproliferative activity with low-nanomolar IC50s
- High purity suitable for analytical and biological studies
- Available in multiple small-scale quantities for research use
- Intended for research use only; not for human or clinical use
AdipoGen Coumarin 314
Chemical. CAS 55804-66-5. Formula C18H19NO4. Molecular Weight 313.35. Coumarin 314 is a rigidized aminocoumarin derivative used as a laser dye with an absorption maximum of 436nm. It can be used as starting material for the synthesis of fluorescent probes. Spectral data lambdamax 436nm in ethanol, epsilon extinction coefficient >39000 at 389-401 nm in ethanol, lambdalaser 504nm.
Sigma Aldrich Fine Chemicals Biosciences Scopoletin >=99% | 92-61-5 | MFCD00006872 | 50MG
Scopoletin >=99% | Purity: >=99% | Mol Wt: 192.17 | 92-61-5 | MFCD00006872 | 50MG
Research Products International Corp Esculin, 500 G
- CAS Number: 531-75-9
- Molecular Formula: C15H16O9 • xH2O
- Molecualr Weight: 340.28 g/mol
eMolecules 7-Methoxy-2-oxochromene-3-carboxylic acid | Combi-Blocks | 20300-59-8 | MFCD00452770 | 220.180 | C11H8O5 | 98.000 | COc1ccc2cc(C(O)=O)c(=O)oc2c1 | 1g | 267167713
7-Methoxy-2-oxochromene-3-carboxylic acid | Combi-Blocks | 20300-59-8 | MFCD00452770 | 220.180 | C11H8O5 | 98.000 | COc1ccc2cc(C(O)=O)c(=O)oc2c1 | 1g | 267167713
Sigma Aldrich Fine Chemicals Biosciences Esculin hydrate >=98.0% (HPLC) | 531-75-9 (anhydrous) | MFCD00149492 | 50G
Esculin hydrate >=98.0% (HPLC) | Purity: >=98.0% (HPLC) | 531-75-9 (anhydrous) | MFCD00149492 | 50G
Medchemexpress LLC 6-Hydroxycoumarin | 6093-68-1 | MFCD00630040 | 500 MG
6-Hydroxycoumarin is a coumarin that exhibits a range of biological activities. It is intended for research use only.
- Anti-inflammatory properties
- Anti-pyretic properties
- Anti-oxidant properties
- Vasodilator properties
- Anti-amoebic properties
- Anti-bacterial properties
- Anti-fungal properties
- Bacteriostatic properties
- Antitumor properties
AdipoGen Coumarin 334
Chemical. CAS 55804-67-6. Formula C17H17NO3. Molecular Weight 283.32. Coumarin 334 is a laser dye with an absorption maximum of 452nm. It is used as starting material for the synthesis of cysteine-selective or pH indicator fluorescent probes. Spectral data lambdamax 452nm, epsilon extinction coefficient >45000 at 449-455 nm in ethanol, lambdalaser 532nm.
Medchemexpress LLC 7-Methylcoumarin | 2445-83-2 | MFCD00006880 | 5 G
7-Methylcoumarin is a coumarin derivative known for its potent hepatoprotective and antioxidant properties. It functions as a mechanism-based inhibitor for CYP2A6, a key enzyme involved in drug metabolism. Studies have shown that it can significantly reduce markers of liver damage, such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB), in models of CCl4-induced liver injury. Additionally, it helps to restore total protein (TP) and albumin (TA) levels and prevent oxidative stress. It also exhibits an ability to decrease the mitotic activity of *A. sativum* promeristem.
- Possesses potent hepatoprotective properties
- Acts as a mechanism-based inhibitor for CYP2A6
- Reduces markers of liver damage
- Restores protein and albumin levels in serum
- Prevents oxidative stress
- Decreases mitotic activity