Coumarins and derivatives
Apexbio Technology LLC Coumarin-3-carboxylic Acid 531-81-7 200mg
Coumarin-3-carboxylic Acid is a coumarin-derived small molecule commonly applied as an investigative tool in biomedical research focusing on signal pathway regulation It is utilized to modulate enzymatic activities and cellular signaling pathways Coumarin-3-carboxylic Acid s biological activity has been studied in the context of its lanthanide complexes for inhibitory effects on cell growth in K-562 cell lines In cell-based studies it demonstrates antiproliferative activity in K-562 cells Based on these pharmacological properties Coumarin-3-carboxylic Acid holds research potential in elucidating biological mechanisms underlying hematologic malignancies and related diseases
Medchemexpress LLC Coumarin-3-carboxylic acid | 531-81-7 | MFCD00006852 | 99.9% | 190.15 g/mol | C10H6O4 | 100 G
Coumarin-3-carboxylic acid is a coumarin derivative provided for research use as a white to off-white solid. It is used as a fluorescent probe for hydroxyl radicals and as a synthetic intermediate in coumarin chemistry. The material is offered in multiple package sizes to support analytical and preparative work.
- High purity suitable for research applications.
- Fluorescent probe for hydroxyl radical detection.
- Available in multiple package sizes including 100 g for scale-up.
- Solid white to off-white appearance, easy to weigh and store.
- Well-characterized chemical identifiers: CAS 531-81-7, C10H6O4.
Medchemexpress LLC 2-oxo-2H-1-benzopyran-3-carboxylic acid | 531-81-7 | MFCD00006852 | 99.9% | 190.15 g/mol | C10H6O4 | 50 G
Coumarin-3-carboxylic acid is a small-molecule research reagent (2-oxochromene-3-carboxylic acid) used as a fluorescent probe for hydroxyl radicals and as a synthetic building block. Supplied as a high-purity solid, it is suitable for in vitro studies and can be formulated for in vivo dosing when required.
Medchemexpress LLC 7-Methoxycoumarin-3-carboxylic acid | 20300-59-8 | MFCD00452770 | 97.0% | 220.18 g/mol | C11H8O5 | 10 G
7-Methoxycoumarin-3-carboxylic acid is a small-molecule fluorescent dye that absorbs in the near-UV (≈345 nm) and emits blue fluorescence (≈450 nm). Supplied as a white to off-white solid, it is used for labeling peptides, HPLC derivatization, and developing FRET-based probes in biochemical assays. It is soluble in DMSO (~8 mg/mL) and typically supplied at 97% purity.
Medchemexpress LLC (2,5-dioxopyrrolidin-1-yl) 7-hydroxy-2-oxochromene-3-carboxylate | 134471-24-2 | MFCD00037568 | >96.0% | 303.22 g/mol | C14H9NO7 | 10 MG
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is an N-hydroxysuccinimide (NHS)-activated fluorescent labeling reagent that introduces a 7-hydroxycoumarin fluorophore onto primary amines. Provided as a solid for research use, it is intended for bioconjugation and fluorescence-based assays.
- Reacts with primary amines via NHS ester chemistry for covalent labeling.
- Provides a blue/UV-excitable coumarin fluorophore suitable for protein, peptide, and nucleic acid labeling.
- Available in small-scale quantities convenient for analytical and preparative labeling.
- High chemical purity suitable for coupling reactions (suppliers report >96%).
- Stable when stored as directed; consult the product datasheet or certificate of analysis for storage and handling details.
Medchemexpress LLC Coumarin 314 | 55804-66-5 | MFCD00051334 | 98.0% | 313.3 g/mol | C18H19NO4 | 500 MG
Coumarin 314 is a fluorescent dye that exhibits intense absorption in the visible region and pronounced solvent-dependent spectral behavior. It is used as a visible-absorbing fluorophore for photophysical studies, fluorescence labeling, and materials research, and is supplied with analytical documentation for research use.
- Intense absorption in the visible region.
- Pronounced solvent-dependent spectral behavior.
- High stated purity of 98.0%.
- Available in small research quantities (100 mg, 250 mg, 500 mg; larger sizes by request).
- Manufacturer provides SDS, COA, and a data sheet for each batch.
- Suitable for fluorescence labeling and photophysical studies.
Medchemexpress LLC 3-aminocoumarin (3-aminochromen-2-one) | 1635-31-0 | MFCD00016965 | 161.16 g/mol | C9H7NO2 | 1 G
3-Aminocoumarin (3-aminochromen-2-one) is an organic intermediate commonly used in coordination chemistry and organic synthesis as a precursor to ligands and metal complexes. Supplied for research use, it is intended for preparative and exploratory synthesis workflows where a well-characterized coumarin derivative is required.
- Serves as an intermediate for synthesis of metal complexes and ligands.
- Suitable for coordination chemistry and related organic synthesis applications.
- Characterized small molecule: formula C9H7NO2, molecular weight 161.16 g/mol.
- Recommended storage: 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month).
- Intended for research use only.
Medchemexpress LLC 3-aminocoumarin (3-aminochromen-2-one) | 1635-31-0 | MFCD00016965 | 99.2% | 161.16 | C9H7NO2 | 250 MG
3-Aminocoumarin (3-aminochromen-2-one) is a coumarin-derived organic intermediate used in research and chemical synthesis. It functions as a building block for the preparation of metal complexes and other functionalized coumarin derivatives, and is supplied as a laboratory research reagent with recommended storage instructions to preserve stability.
- Coumarin-derived intermediate for organic synthesis.
- Suitable for synthesis of metal complexes and functionalized derivatives.
- Molecular formula C9H7NO2; molecular weight 161.16 g/mol.
- Recommended storage: solid at 4°C, protect from light; solutions -80°C (6 months) or -20°C (1 month).
- Provided as a research reagent; follow appropriate safety and handling procedures.
Medchemexpress LLC 7-methoxycoumarin-3-carboxylic acid | 20300-59-8 | 97.0% | 220.18 g/mol | C11H8O5 | 25 G
7-Methoxycoumarin-3-carboxylic acid is a coumarin-based fluorescent dye used for labeling peptides and synthesizing fluorescent probes. It provides ultraviolet excitation and blue emission suitable for fluorescence assays, probe development, and HPLC derivatization. The material is supplied at research-grade purity for laboratory use.
- High purity (97.0%).
- Excitation 345 nm, emission 450 nm.
- Molecular weight 220.18 g/mol.
- Chemical formula C11H8O5.
- Available in multiple pack sizes including 25 g.
Medchemexpress LLC Coumarin boronic aci 5mg
Coumarin boronic acid is a fluorescent probe The excitation and emission wavelengths of coumarin boronic acid are set to 360 nm and 430 nm respectively Coumarin boronic acid can be used to monitor the formation of amino acid and protein hydroxyl peroxides in real time which is beneficial for understanding the mechanisms of oxidative stress and protein post-translational modification[1]
Medchemexpress LLC 4-methoxycoumarin | 20280-81-3 | MFCD00017349 | >99.0% | 176.17 g/mol | C10H8O3 | 25 MG
4-methoxycoumarin is a coumarin derivative reported to show antibacterial activity against R. solanacearum and is supplied for research use in small quantities for analytical and biological testing.
- Shows reported antibacterial activity against R. solanacearum.
- Molecular formula: C10H8O3.
- Molecular weight: 176.17 g/mol.
- CAS number: 20280-81-3.
- Typical pack size: 25 mg; intended for research use.
- Reported purity (supplier): >99%.
Medchemexpress LLC 4-Methoxycoumarin | 20280-81-3 | 176.17 g/mol | C10H8O3 | 1 G
4-Methoxycoumarin is a coumarin derivative used in research with reported antibacterial activity against Ralstonia solanacearum. It is supplied as a powder with chemical formula C10H8O3 (molecular weight 176.17 g/mol) and CAS number 20280-81-3. The compound is soluble in DMSO (100 mg/mL; ultrasonic assistance recommended), and storage guidance and solution stability are provided for laboratory handling.
- Antibacterial activity against Ralstonia solanacearum
- Chemical formula C10H8O3 and molecular weight 176.17 g/mol
- CAS number 20280-81-3 for unambiguous identification
- High DMSO solubility: 100 mg/mL (requires ultrasonic)
- Storage stability: powder -20°C (up to 3 years), 4°C (up to 2 years); in solvent -80°C (6 months), -20°C (1 month)
- Solution preparation guidance from 1 g: 1 mM = 5.6763 mL, 5 mM = 1.1353 mL, 10 mM = 0.5676 mL
Medchemexpress LLC Coumarin 480 | 41267-76-9 | MFCD00041844 | 100.0% | 255.31 g/mol | C16H17NO2 | 25 MG
Coumarin 480 (Coumarin 102) is a high-purity fluorescent laser dye used in fluorescence spectroscopy, laser applications, and optical research. It shows strong emission near 480 nm and is supplied as a research-grade reagent for imaging, sensor development, and photophysical studies. Users should follow the product SDS for safe handling and storage.
- High purity (99.95%).
- Strong fluorescence emission near 480 nm.
- Suitable for fluorescence spectroscopy and laser dye applications.
- Useful for sensor development and imaging studies.
- Provided as a research reagent in small vials.
Medchemexpress LLC My-1076 | 3008262-76-5 | MFCD35444266 | 99.1% | 539.57 g·mol-1 | C29H33NO9 | 10 MG
MY-1076 is a small-molecule inhibitor of Yes-associated protein (YAP) used for laboratory research. It induces YAP degradation and apoptosis and shows potent antiproliferative activity against several cancer cell lines with low-nanomolar IC50s. Reported properties include CAS 3008262-76-5, formula C29H33NO9, molecular weight 539.57 g·mol-1, and high reported purity.
- Induces YAP degradation and apoptosis in vitro
- Potent antiproliferative activity with low-nanomolar IC50s
- High purity suitable for analytical and biological studies
- Available in multiple small-scale quantities for research use
- Intended for research use only; not for human or clinical use