Flavonoids
TARGETMOL CHEMICALS INC Epigallocatechin-3-3-O-methyl
Also available in 1 mL, 5 mg, 10 mg, 25 mg and bulk. Please contact Fisher for quotes. (-)-Epigallocatechin-3-(3''-O-methyl) gallate ((-)-EGCG-3''-O-ME) is a natural product isolated from tea leaves with potent antioxidant, cytotoxic, and antibacterial properties, and it improves the adhesive stability of etching rinsing adhesives to dentin. Purity 99.59%
Medchemexpress LLC 4'-hydroxyflavone | 4143-63-9 | MFCD00017687 | 97.0% | 238.24 g/mol | C15H10O3 | 5 MG
4'-Hydroxyflavone is a small-molecule flavone provided for research use. It has the chemical formula C15H10O3, a molecular weight of 238.24 g/mol, and is reported to inhibit aldose reductase (IC50 = 12 μM). The material is intended as a reference reagent for biochemical, pharmacological, and enzymology studies.
- High purity (97.0%) suitable for analytical and biological assays.
- Reported aldose reductase inhibitor (IC50 = 12 μM) for target validation studies.
- Well-characterized chemical identity and molecular properties.
- Available in small pack sizes appropriate for research applications.
- Suitable for biochemical assays, enzymology, and screening workflows.
Selleck Chemical LLC 6-Hydroxyflavone (6-HF) S3634-25mg
6-Hydroxyflavone a naturally occurring flavonoid binds to GABAA receptors with moderate affinity and acts as a partial agonist of GABAA receptors
Medchemexpress LLC 7-Hydroxyflavone | 6665-86-7 | 10 MG
7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis* with anti-inflammatory activity. It protects renal cells from nicotine (NIC)-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway. This compound inhibits PKM2 with an IC50 of 2.12 μM and also inhibits COX-2 and 5-LOX with IC50s of 27 μg/mL and 33 μg/mL, respectively. 7-Hydroxyflavone is orally active.
- Isolated from *Clerodendrum phlomidis*.
- Exhibits anti-inflammatory activity.
- Protects renal cells from nicotine-associated cytotoxicity.
- Inhibits PKM2, COX-2, and 5-LOX.
- Orally active.
- Inhibits EV71 3C protease and viral replication.
- Antioxidant properties: decreases MDA and ROS, increases SOD and GSH.
- Ameliorates ischemia/reperfusion injury and neuropathic pain.
- Improves hepatic steatosis and regulates blood glucose metabolism in NAFLD models.
Medchemexpress LLC Chrysin-7-O-glucuronide | 35775-49-6 | 1 MG
Chrysin-7-O-glucuronide is a flavonoid extracted from *Scutellaria baicalensis* that exhibits antioxidant activity. It is intended for research use only.
- Purity: 99.47%
- Source: Flavonoid extracted from *Scutellaria baicalensis*.
- Activity: Antioxidant activity.
- Appearance: Solid, off-white to yellow color.
- Solubility (in vitro): 50 mg/mL (116.18 mM) in DMSO.
- Structure classification: Flavonoids, flavones, phenols, monophenols.
- Initial source: Plants (Leguminosae, Bignoniaceae, Labiatae).
Medchemexpress LLC 7-Hydroxyflavone | 6665-86-7 | MFCD00006835 | 50 MG
7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis* that exhibits anti-inflammatory activity. It protects renal cells from nicotine-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway. This orally active compound also inhibits PKM2, COX-2, and 5-LOX, and has demonstrated antioxidant activity and efficacy in various animal models.
- Isolated from *Clerodendrum phlomidis*
- Exhibits anti-inflammatory activity
- Protects renal cells from nicotine-associated cytotoxicity
- Inhibits PKM2, COX-2, and 5-LOX
- Orally active
- Reduces malondialdehyde (MDA) and reactive oxygen species (ROS) levels
- Increases superoxide dismutase (SOD) and glutathione (GSH) levels
- Ameliorates ischemia/reperfusion injury
- Improves high-fat diet-induced non-alcoholic fatty liver disease and obesity
- Purity of 99.89%
- Appearance is a white to off-white solid
Medchemexpress LLC Hesperidin (Standard) | 520-26-3 | C₂₈H₃₄O₁₅ | 50 MG
Hesperidin (Standard) is the analytical standard for Hesperidin, intended for research and analytical applications. Also known as Hesperetin 7-rutinoside, this flavanone glycoside is isolated from citrus fruits and possesses numerous biological properties, including decreasing inflammatory mediators, significant antioxidant effects, and exhibiting antitumor and antiallergic activities. It serves as a reference standard for assays in qualitative, quantitative, and methodological research experiments.
- Analytical standard for hesperidin
- Intended for research and analytical applications
- Isolated from citrus fruits
- Decreases inflammatory mediators
- Significant antioxidant effects
- Exhibits antitumor and antiallergic activities
- Used as a reference standard in HPLC, GC, and MS
Medchemexpress LLC Hesperidin (Standard) | 520-26-3 | C28H34O15 | 1 ML
Hesperidin, also known as Hesperetin 7-rutinoside, is a flavanone glycoside naturally isolated from citrus fruits. This compound is recognized for its various biological properties, including significant antioxidant effects, the ability to decrease inflammatory mediators, and demonstrated antitumor and antiallergic activities.
- Decreases inflammatory mediators
- Significant antioxidant effects
- Exhibits antitumor activity
- Exhibits antiallergic activity
- Supports research in cancer
- Targets apoptosis
- Targets autophagy
- Targets reactive oxygen species (ROS)
- Functions as an endogenous metabolite
Cayman Chemical HesperIdIn methylchalconC 250g
A C. aurantium extract that contains hesperidin methylchalcone, among other compounds
Medchemexpress LLC 4H-1-benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2S)- | 520-33-2 | MFCD00075646 | 99.12% | 302.28 | 100 MG
Hesperetin is a natural flavanone found in citrus that acts as a potent, orally active, broad-spectrum inhibitor against human UGT activity. It induces apoptosis through p38 MAPK activation and displays various bioactivities, including antioxidant, anti-inflammatory, and anti-cancer properties. Hesperetin can induce cell-cycle arrest at the G2/M phase, reduce Bcl-2, enhance BaxM, and inhibit the NF-κB receptor to induce apoptosis.
- Purity: 99.12%
- CAS no.: 520-33-2
- Appearance: solid
- Color: white to off-white
- Molecular weight: 302.28
- Formula: C16H14O6
- Structure classification: flavonoids, flavanones
- Initial source: plants other families
- Storage: powder at -20°C for 3 years, 4°C for 2 years. In solvent at -80°C for 6 months, -20°C for 1 month.
- Solubility: in DMSO, 125 mg/mL (413.52 mM).