Flavonoids
Cayman Chemical EpIcatechIn Galate 10mg
A natural catechin which inhibits the growth of cancer cells and has anti-inflammatory effects; has potent antioxidant activity and facilitates the killing of methicillin-resistant strains of S. aureus
AdipoGen Luteolin
Chemical. CAS 491-70-3. Formula C15H10O6. MW 286.2. Synthetic. Anticancer and antimetastatic. alpha-Glucosidase inhibitor. Topoisomerase I Inhibitor. Apoptosis inducer. Anti-inflammatory. 15-Lipoxygenase 15-LOX inhibitor. IL-6 production inhibitor. Fatty acid synthase FAS inhibitor. Antioxidant. Free radical scavenger. Antiadipogenic. PPAR-gamma inhibitor. Neuroprotective. Monoamine transporter activator. Inhibitor of phosphodiesterases 1-5 PDE1-5. PKCepsilon and Src kinase inhibitor. HDAC inhibitor. Autophagy modulator Phosphatidylinositol 3-kinase PI3K / Akt signaling inhibitor. p90 ribosomal S6 kinase RSK1/RSK2 kinase activity inhibitor.
Cayman Chemical Apigenin Inhibitors
Inhibits CK2 activity in the renal cortex with an IC50 value of 30 µM; potent inhibitor of NO and PGE2 biosynthesis by reducing iNOS and COX-2 expression
![Medchemexpress LLC 3-oxo-3-[[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyox | 86546-87-4 | 97.0% | 518.42 g·mol⁻¹ | C24H22O13 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000289621.png-250.jpg)
Medchemexpress LLC 3-oxo-3-[[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyox | 86546-87-4 | 97.0% | 518.42 g·mol⁻¹ | C24H22O13 | 10 MG
Apigenin 7-O-malonylglucoside is a flavonoid glycoside found in chrysanthemum flowers, supplied for research use as a high-purity analytical standard. It is used in studies of natural product chemistry, flavonoid metabolism, and bioactivity assays, and as a reference compound for chromatographic and mass-spectrometric method development.
- Natural product flavonoid glycoside found in chrysanthemum flowers.
- Useful as a reference standard for HPLC and LC-MS method development.
- Suitable for in vitro studies of flavonoid metabolism and bioactivity.
- High purity (>97%) appropriate for analytical and biochemical research.
- Provided as a solid in milligram-scale quantities for laboratory use.
Cayman Chemical Luteolin Inhibitors
A common dietary phenolic flavone; inhibits soybean and reticulocyte 15-lipoxygenases (IC50 = 0.6 µM); inhibits the release of TNFα from neutrophils; inhibits matrix metalloproteinases
Medchemexpress LLC Luteolin 7-O-glucuronide | 29741-10-4 | 462.36 | 1 MG
Luteolin 7-O-glucuronide inhibits Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, and 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, and MMP-13, respectively. It also inhibits NO production and mRNA expression of inflammatory mediators (COX-2, IL-6, IL-1β, and TNF-α) as well as NF-κB, p38, and JNK activation in LPS-stimulated RAW 264.7 macrophages. In a mouse sleep deprivation model, this compound improved depression-like and stress coping behaviors.
- Inhibits matrix metalloproteinases (MMPs) activities.
- Reduces NO production and inflammatory mediators.
- Inhibits NF-κB, p38, and JNK activation.
- Improves depression-like and stress coping behaviors.
- Suitable for in vitro and in vivo studies.
TARGETMOL CHEMICALS INC LUTEOLIN 7-O-GLUCURONIDE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Luteolin 7-O-glucuronide (Luteolin-7-glucuronide) possesses antioxidant activities. purity: 99%
Medchemexpress LLC Apigenin-7-glucuronide | 29741-09-1 | 446.36 | 1 MG
Apigenin-7-glucuronide is a compound that inhibits Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, and 0.27 μM for MMP-3, MMP-8, MMP-9, and MMP-13, respectively. This product is for research use only.
- Inhibits matrix metalloproteinases (MMPs)
- Effective against MMP-3, MMP-8, MMP-9, and MMP-13
- Soluble in DMSO up to 250 mg/mL
Medchemexpress LLC Apigenin | 520-36-5 | 270.24 | 1 G
Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor that inhibits cytochrome P450 2C9 in a purified enzyme system. It demonstrates dose- and time-dependent inhibition of cell proliferation in SGC-7901 cells.
- Competitive CYP2C9 inhibitor with a Ki of 2 μM.
- Inhibits cytochrome P450 2C9 in a purified, reconstituted enzyme system.
- Demonstrates inhibition of cell proliferation in SGC-7901 cells in a dose- and time-dependent manner.
- Achieves growth inhibition rates of 38%, 71%, and 99% at 20, 40, and 80 μM, respectively, on the 7th day.
- Cloning efficiency in SGC-7901 cells treated with 80 μM for 24 and 48 hours was 9.8% and 5%, respectively.
Medchemexpress LLC Luteolin-4'-O-glucoside | 6920-38-3 | 5 MG
Luteolin-4'-O-glucoside is identified as an IL-5 inhibitor with an IC50 of 3.7 μM. It exhibits resistance to hyperuricemia and acute gouty arthritis activity, and also demonstrates anticancer activity.
- It is an interleukin-5 (IL-5) inhibitor.
- It has an IC50 of 3.7 μM against IL-5.
- It resists hyperuricemia.
- It resists acute gouty arthritis activity.
- It shows anticancer activity.
- It exhibits cytotoxic activity against NCI-H929, U266, and OPM2 cell lines.
Medchemexpress LLC (+)-epicatechin (dexepicatechin) | 35323-91-2 | MFCD00075648 | 99.6% | 10 MG
(+)-Epicatechin is a chiral catechin and polyphenolic antioxidant supplied as a research reagent. It is commonly used in biochemical and analytical assays to evaluate antioxidant activity and enzyme inhibition. The compound is a white to off-white solid with molecular formula C15H14O6 and a molecular weight of 290.27 g/mol. Purity is typically reported at about 99.6%.
- High purity suitable for analytical applications
- Solid form convenient for storage and handling
- Used in antioxidant and cyclooxygenase inhibition studies
- Soluble in common organic solvents for stock solutions
- Provided in a small quantity suitable for early-stage experiments
Medchemexpress LLC Luteolin 7-O-glucuronide | 29741-10-4 | 98.7% | 462.36 | C21H18O12 | 10 MG
Luteolin 7-O-glucuronide is a flavone glycoside used as a research reagent to study matrix metalloproteinase (MMP) inhibition and inflammation-related pathways. It is supplied as a light-yellow solid and as a DMSO solution, and is provided at high purity for biochemical assays and analytical standards.
- Cas number: 29741-10-4.
- Molecular weight: 462.36.
- Typical purity: 98.7% (batch level).
- Physical forms: solid and 10 mM solution in DMSO.
- Typical package sizes include 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.
- Common applications: enzymatic inhibition assays and analytical standardization.
Cayman Chemical LuteolIn 7-O-GlucuronIde 10mg
A flavonoid with antioxidant, enzyme inhibitory, and anti-inflammatory properties; scavenges DPPH radicals in a cell-free assay (IC50 = 80.6 μM); inhibits porcine α-amylase and yeast α-glucosidase in vitro (IC50s = 61.5 and 14.7 μM, respectively); inhibits rat aldose reductase in vitro (IC50 = 0.7 μM) and sorbitol accumulation in isolated rat lens at 5 μg/ml; inhibits LPS-induced cytokine release from RAW 264.7 macrophages in a dose-dependent manner
Cayman Chemical Luteolin Inhibitors
A common dietary phenolic flavone; inhibits soybean and reticulocyte 15-lipoxygenases (IC50 = 0.6 µM); inhibits the release of TNFα from neutrophils; inhibits matrix metalloproteinases
TARGETMOL CHEMICALS INC Apigenin-7-O-2G-rhamnosylgenti
Also available in 1 mL, 1 mg, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Apigenin-7-O-(2G-rhamnosyl)gentiobioside is a flavonoid glycoside compound extracted from [Lonicera gracilipes var. glandulosa]. Purity 99.71%