Flavonoids
Abcam Apigenin, Anticancer agent, 50MG
MW 270.24 Da, Purity >98%. Plant flavone. Antioxidant, anti-inflammatory and anticancer properties. Effects a wide range of molecular targets including caspases, fatty acid synthase, topoisomerase and nuclear factor-κB.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Luteolin-3',7-diglucoside | 52187-80-1 | 5 MG
Luteolin-3′,7-diglucoside is a glycoside that can be isolated from *R. luteolin*. It significantly inhibits cataracts induced in ovine lenses and also inhibits the activity of *Ureaplasma urealyticum* ATCC and clinical strains.
- Glycoside isolated from *R. luteolin*.
- Significantly inhibits cataracts induced in ovine lenses.
- Inhibits activity of *Ureaplasma urealyticum* ATCC and clinical strains.
- High purity of 97.0%.
- Appears as a solid, light yellow to yellow.
Medchemexpress LLC (-)-Epicatechin | 490-46-0 | 95.6% | 290.27 | 1 MG
(-)-Epicatechin is the analytical standard of (-)-Epicatechin, intended for research and analytical applications. It inhibits cyclooxygenase-1 (COX-1) and the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB. This analytical standard is commonly used in qualitative, quantitative, and methodological research experiments in techniques such as HPLC, GC, and MS.
- Suitable for research and analytical applications.
- Inhibits cyclooxygenase-1.
- Blocks nuclear localization of p65 subunit of NF-κB.
- Used in qualitative research experiments.
- Used in quantitative research experiments.
- Used in methodological research experiments.
- Compatible with HPLC, GC, and MS techniques.
Medchemexpress LLC Luteolin monohydrate | 6113-16-2 | 99.1% | 304.25 g/mol | C15H12O7 | 1 ML
Luteolin monohydrate is the monohydrate form of luteolin, a flavonoid research reagent reported to have anti-inflammatory and anticancer activity. It is supplied as a ready-to-use 10 mM solution in DMSO (1 mL) and as solid quantities for laboratory use, and is intended for research applications.
- Ready-to-use 10 mM solution in DMSO for convenient dosing
- High purity (99.1%) for reproducible results
- Suitable for cell-based and biochemical assays
- Solid forms available for bulk use (100 MG-5 G)
- Molecular formula C15H12O7 and molecular weight 304.25 g/mol
- Storage recommendations provided for solid and solution forms
Medchemexpress LLC (-)-epicatechin | 490-46-0 | MFCD00075648 | ≥97.0% | 290.27 | C15H14O6 | 10 MG
(-)-Epicatechin is a naturally occurring flavanol (catechin) used as a research reagent and analytical standard. It is used in biochemical and cellular assays to study cyclooxygenase activity and inflammatory signaling pathways.
Medchemexpress LLC Luteolin monohydrate | 6113-16-2 | 99.1% | 304.25 | C15H12O7 | 100 MG
Luteolin monohydrate is the monohydrate form of luteolin, a naturally occurring flavonoid used in biological research. It acts as a potent Nrf2 inhibitor and has reported anti-inflammatory and anticancer activities, including induction of apoptosis and cell-cycle arrest in various cancer cell lines.
- Monohydrate form suitable for research applications.
- Potent Nrf2 inhibitor with reported anti-inflammatory activity.
- Induces apoptosis and cell-cycle arrest in multiple cancer cell lines.
- High purity (99.13%).
- Chemical identifiers: CAS 6113-16-2; molecular weight 304.25; formula C15H12O7.
- Available as solid and as a DMSO solution format.
Medchemexpress LLC Apigenin 7-glucoside | 578-74-5 | MFCD00016787 | 432.38 | 50 MG
Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside) exhibits significant anti-proliferative and antioxidant activity and scavenges reactive oxygen species (ROS). It is for research use only and not sold to patients. It is available as a solid, light yellow to yellow in color.
- Exhibits significant anti-proliferative and antioxidant activity
- Scavenges reactive oxygen species (ROS)
- Induces differentiation of CD34+ cells towards erythroid lineage
- Inhibits myeloid differentiation
- Available as a solid, light yellow to yellow in color
Medchemexpress LLC Apigenin (Standard) | 520-36-5 | 270.24 | 5 MG
Apigenin (Standard) is the analytical standard of Apigenin, intended for research and analytical applications. It is a competitive CYP2C9 inhibitor with a Ki of 2 μM. This analytical standard is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS. Features and benefits include:
- Purity: 98.82%
- Appearance: solid
- Color: yellow to brown
- Structure classification: flavonoids, phenols
- Initial source: plants Compositae Baccharis sarothroides A.Gray, plants Umbelliferae
- Endogenous metabolite: human gut microbiota metabolites
Medchemexpress LLC Luteolin 7-O-glucuronide | 29741-10-4 | 462.36 | 1 ML
Luteolin 7-O-glucuronide is an inhibitor of Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, and 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, and MMP-13, respectively. It is intended for research use only.
- Inhibits NO production and mRNA expression of inflammatory mediators in LPS-stimulated RAW 264.7 macrophages.
- Inhibits NF-κB, p38, and JNK activation in LPS-stimulated RAW 264.7 macrophages.
- Improves depression-like and stress coping behaviors in mouse sleep deprivation models.
- Reduces increased immobility time and plasma corticosterone levels.
- Reduces TNF-α and IL-1β levels and increases BDNF mRNA expression in the hippocampus of sleep-deprived mice.
Medchemexpress LLC Apigenin (standard) | 520-36-5 | 270.24 | 50 MG
Apigenin (Standard) is an analytical standard intended for research and analytical applications. It is a competitive CYP2C9 inhibitor with a Ki of 2 μM and serves as a reference standard for assays.
- Analytical standard for research and analytical applications
- Competitive CYP2C9 inhibitor
- Reference standard for assays
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications