Phenols
Cayman Chemical p-chloro PhenylalnIn 5g
An inhibitor of tryptophan hydroxylase (Ki = 300 µM); a competitive inhibitor in vitro and an irreversible inhibitor in vivo; depletes serotonin to undetectable levels in rats after six days at 300 mg/kg; has commonly been used to deplete brain serotonin levels in animal studies of the serotonergic system
Medchemexpress LLC N-p-tosylglycine | 1080-44-0 | MFCD00045898 | 98.2% | 229.26 g/mol | C9H11NO4S | 25 G
N-p-tosylglycine is a tosyl-protected derivative of glycine supplied as a laboratory research reagent for use in organic synthesis and biochemical studies. It is provided as a white to off-white powder with high purity and is intended for research use only.
- Tosyl-protected glycine derivative
- Chemical formula C9H11NO4S
- Molecular weight 229.26 g/mol
- Cas number 1080-44-0
- Purity 98.2%
- Available in 25 g and 100 g sizes
- Intended for research use only
TARGETMOL CHEMICALS INC ORELABRUTINIB 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Orelabrutinib (ICP-022) is an orally active and irreversible inhibitor of Bruton's tyrosine kinase (BTK). purity: 99%
Medchemexpress LLC Gastric Inhibitory Peptide, porcine | 11063-17-5 | >99.1% | 4975.55 | 5 MG
Gastric Inhibitory Peptide, porcine is a glucose-dependent insulinotropic polypeptide, a 42 amino acid intestinal hormone with effects on fat and glucose metabolism.
- Glucose-dependent insulinotropic polypeptide
- 42 amino acid intestinal hormone
- Affects fat and glucose metabolism
- Targets insulin receptor
- Involves protein tyrosine kinase/RTK pathway
- Purity: >99.1%
- Molecular weight: 4975.55
- CAS number: 11063-17-5
- Appearance: Solid
- Color: White to light yellow
Medchemexpress LLC amyloid P-IN-1 | 1819986-22-5 | 99.6% | 656.68 | 1 ML
amyloid P-IN-1 is a compound utilized in the research of diseases and disorders characterized by the depletion of serum amyloid P component (SAP). This includes conditions such as amyloidosis, Alzheimer's disease, type 2 diabetes mellitus, and osteoarthritis.
- Formulated for research applications.
- Solution provided at 10mM concentration in DMSO.
- High purity for consistent experimental results.
- Stable under recommended storage conditions for extended periods.
Medchemexpress LLC STO-609 | 52029-86-4 | 98.20% | 314.29 | 5 MG
STO-609 is a selective and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK). It inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 ~0.02 g/ml.
- Inhibits activities of recombinant CaM-KKα and CaM-KKβ isoforms with Ki values of 80 and 15 ng/mL, respectively.
- Inhibits their autophosphorylation activities.
- Highly selective for CaM-KK without significant effect on downstream CaM kinases (CaM-KI and -IV).
- Inhibits constitutively active CaM-KKα as well as the wild-type enzyme.
- Suppresses Ca2+-induced activation of CaM-KIV in transfected HeLa cells in a dose-dependent manner.
- Reduces endogenous activity of CaM-KK in SH-SY5Y neuroblastoma cells at 1μg/mL (80% inhibitory rate).
TARGETMOL CHEMICALS INC CGP 20376 5MG
Also available in 1 mg 10 mg 25 mg 50 mg and bulk. Please contact Fisher for quotes. CGP 20376 is a benzothiazole compound an anthelmintic with dual dose-dependent modulation of in vitro effects on the respiratory burst of eosinophils and antifibrillatory properties. purity: 91%
Medchemexpress LLC 5'-ODMT cEt N-Bz A Phosphoramidite (amidite) | 1197033-19-4 | >98.5% | 899.97 | 25 MG
This nucleoside phosphoramidite monomer is used for synthesizing locked nucleic acid (LNA) analog oligonucleotides, acting as a building block for antisense oligonucleotides (ASOs) to target complementary RNA sequences. Its 2',4'-constrained ethyl (cEt) modification enhances hybridization affinity and mismatch discrimination with RNA, improving oligonucleotides' resistance to exonuclease digestion and enabling gene expression regulation.
- Synthesizes locked nucleic acid (LNA) analog oligonucleotides.
- Enhances RNA hybridization affinity and mismatch discrimination.
- Improves oligonucleotide resistance to exonuclease digestion.
- Facilitates RNase H-dependent mRNA degradation.
- Used in antisense drug development and gene research.
- Improves qPCR probe/primer stability and melting temperature.
Medchemexpress LLC P-CAB agent 2 hydrochloride | 2209911-80-6 | C22H26ClFN2O4S | 1 ML
P-CAB agent 2 hydrochloride is a potent and orally active potassium-competitive acid blocker and a gastric acid secretion inhibitor. It inhibits H+/K+-ATPase activity with an IC50 value of <100 nM. It also inhibits the hERG potassium channel with an IC50 value of 18.69 μM. This agent shows no acute toxicity and inhibits histamine-induced gastric acid secretion.
- Potent and orally active potassium-competitive acid blocker.
- Inhibits gastric acid secretion.
- Inhibits H+/K+-ATPase activity with an IC50 value of <100 nM.
- Inhibits hERG potassium channel with an IC50 value of 18.69 μM.
- Shows no acute toxicity.
- Effectively inhibits histamine-induced gastric acid secretion.