Phenols
eMolecules 234081-94-8 | 8-(tert-Butoxy)-8-oxooctanoic acid | Synthonix - Stock | MFCD28505597 | 230.304 | C12H22O4 | 97.000 | CC(C)(C)OC(=O)CCCCCCC(O)=O | 250mg | 483373604
8-(tert-Butoxy)-8-oxooctanoic acid | Synthonix - Stock | 234081-94-8 | MFCD28505597 | 230.304 | C12H22O4 | 97.000 | CC(C)(C)OC(=O)CCCCCCC(O)=O | 250mg | 483373604
eMolecules 543-24-8 | N-Acetylglycine | Combi-Blocks | MFCD00004275 | 117.104 | C4H7NO3 | 98.000 | CC(=O)NCC(O)=O | 1kg | 290696421
N-Acetylglycine | Combi-Blocks | 543-24-8 | MFCD00004275 | 117.104 | C4H7NO3 | 98.000 | CC(=O)NCC(O)=O | 1kg | 290696421
BIOHIPPO h/m EGFR-sh-RFP-Puro
h/m EGFR-sh-RFP-Puro shRNA lentiviral vector expressing RFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m EGFR shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse epidermal growth factor receptor (EGFR) The shRNA has been validated to meet or exceed 70% knockdown of EGFR using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
eMolecules 77-86-1 | Tris(hydroxymethyl)aminomethane | Combi-Blocks | MFCD00004679 | 121.136 | C4H11NO3 | 95.000 | NC(CO)(CO)CO | 1kg | 335346090
Tris(hydroxymethyl)aminomethane | Combi-Blocks | 77-86-1 | MFCD00004679 | 121.136 | C4H11NO3 | 95.000 | NC(CO)(CO)CO | 1kg | 335346090
Medchemexpress LLC Posenacaftor (sodium) | 2095064-06-3 | 99.8% | 467.49 | 10 MG
Posenacaftor sodium is a cystic fibrosis transmembrane regulator (CFTR) protein modulator used in research for cystic fibrosis (CF). It acts as a CFTR corrector, designed to fix and restore the function of defective and misfolded CFTR protein, allowing it to move to the cell surface and function as a chloride channel, thereby helping to maintain fluid balance in the airways.
- Corrects folding and trafficking of CFTR protein
- Used for cystic fibrosis research
- Restores function of defective CFTR protein
- Helps maintain fluid balance in airways
TARGETMOL CHEMICALS INC ABT530 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. ABT530 (Pibrentasvir) is an HCV NS5A inhibitor with EC50s ranging from 1.4-5.0 pM against HCV replicons containing NS5A from genotypes 1-6. purity: 99%
Medchemexpress LLC Hy-078020 (compound III-4) | 2756222-90-7 | 98.9% | 515.09 g/mol | C32H35ClN2O2 | 10 MG
This small-molecule compound is a selective, orally active antagonist of the histamine H1 receptor with reported in vitro potency (H1 IC50 = 24.12 nM). It is supplied for research use with defined purity and storage recommendations.
- Selective, orally active histamine H1 receptor antagonist (H1 IC50 = 24.12 nM).
- Demonstrates selectivity versus muscarinic receptor (mAChR3 IC50 > 10 μM).
- High purity (98.9%) as supplied.
- Available as 10 mg powder and 10 mM solution in DMSO (1 mL).
- Storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (up to 6 months).
- Suitable for in vitro pharmacology and allergic disease research models.
Medchemexpress LLC Maprotiline (hydrochloride) | 10347-81-6 | 100.0% | 1 ML
Maprotiline hydrochloride is a highly selective noradrenergic reuptake inhibitor with strong antidepressant, antitumor, and neuropathic pain-relieving effects. It is orally active and induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1.
- Highly selective noradrenergic reuptake inhibitor
- Exhibits antidepressant, antitumor, and neuropathic pain-relieving effects
- Orally active
- Induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1
- Inhibits growth and metastasis of liver cancer cells
- Regulates cholesterol biosynthesis
- Inhibits tumor growth in liver cancer mouse models without obvious toxicity
- Attenuates neuropathic pain in mice
![eMolecules 13965-03-2 | Bis(triphenylphosphine) palladiuml(II) dichloride | Chem-Impex | MFCD00009593 | 701.900 | C36H30Cl2P2Pd | 60.000 | [Cl-].[Cl-].[Pd++].c1ccc(cc1)P(c1ccccc1)c1ccccc1.c1ccc(cc1)P(c1ccccc1)c1ccccc1 | 100g | 112760658](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000492785.jpg-250.jpg)
eMolecules 13965-03-2 | Bis(triphenylphosphine) palladiuml(II) dichloride | Chem-Impex | MFCD00009593 | 701.900 | C36H30Cl2P2Pd | 60.000 | [Cl-].[Cl-].[Pd++].c1ccc(cc1)P(c1ccccc1)c1ccccc1.c1ccc(cc1)P(c1ccccc1)c1ccccc1 | 100g | 112760658
Bis(triphenylphosphine) palladiuml(II) dichloride | Chem-Impex | 13965-03-2 | MFCD00009593 | 701.900 | C36H30Cl2P2Pd | 60.000 | [Cl-].[Cl-].[Pd++].c1ccc(cc1)P(c1ccccc1)c1ccccc1.c1ccc(cc1)P(c1ccccc1)c1ccccc1 | 100g | 112760658
Apexbio Technology LLC DiscoveryProbe™ Anti-infection Compound Library Plus 100uL/well(10 mM solution),96 Well Deep Well Plate
DiscoveryProbe Anti-infection Compound Library comprises 367 bioactive small-molecule compounds with demonstrated anti-infective activities against bacterial viral fungal or parasitic pathogens Compounds selected have documented mechanisms of action covering inhibition of pathogenic replication interference with cell wall synthesis disruption of membrane integrity and modulation of microbial-specific metabolic pathways Many included agents have been clinically approved by FDA or EMA aiding translational research efforts Representative compounds such as fluconazole azithromycin ribavirin and mebendazole are encompassed The library provides a relevant tool for bio-pharmaceutical researchers conducting high-throughput screening assays mechanistic studies and identification of novel therapeutic approaches in infectious disease characterization and anti-infective drug discovery
Medchemexpress LLC N-p-tosylglycine | 1080-44-0 | MFCD00045898 | 98.2% | 229.26 g/mol | C9H11NO4S | 25 G
N-p-tosylglycine is a tosyl-protected derivative of glycine supplied as a laboratory research reagent for use in organic synthesis and biochemical studies. It is provided as a white to off-white powder with high purity and is intended for research use only.
- Tosyl-protected glycine derivative
- Chemical formula C9H11NO4S
- Molecular weight 229.26 g/mol
- Cas number 1080-44-0
- Purity 98.2%
- Available in 25 g and 100 g sizes
- Intended for research use only
Medchemexpress LLC ICCB-19 hydrochloride | 1803605-68-6 | 99.3% | 291.84 | 25 MG
ICCB-19 hydrochloride is an indirect inhibitor of RIPK1 kinase activity and a TRADD (TNFRSF1A associated via death domain) inhibitor. It functions by binding with the N-terminal domain of TRADD (TRADD-N), which disrupts its binding to both TRADD-C and TRAF2. This compound effectively induces autophagy and the degradation of long-lived proteins.
- Inhibits Bortezomib-induced apoptosis and RIPK1-dependent apoptosis (RDA) with an IC50 of about 1 μM.
- Promotes autophagy via K63-linked ubiquitination of beclin 1.
- Reduces inflammatory responses in Tradd-/- mice.
- Reduces expression of TNF-induced inflammatory target gene products and cytokines.