Phenols
Medchemexpress LLC Tranylcypromine hydrochloride | 1986-47-6 | 99.91% | 169.66 | 100 MG
Tranylcypromine hydrochloride is an irreversible inhibitor of lysine-specific demethylase 1 (LSD1/BHC110) and monoamine oxidase (MAO). It effectively inhibits LSD1, MAO A, and MAO B with specified IC50s. This compound is utilized for research applications, particularly those related to depression.
- Irreversible inhibitor of lysine-specific demethylase 1 (LSD1/BHC110).
- Irreversible inhibitor of monoamine oxidase (MAO).
- Inhibits LSD1 with an IC50 of 20.7 μM.
- Inhibits MAO A with an IC50 of 2.3 μM.
- Inhibits MAO B with an IC50 of 0.95 μM.
- Suitable for research related to depression.
- Supplied as a white to yellow solid.
- Requires sealed storage at 4°C, away from moisture.
- Shows specific derepression of OCT4 transcription in vitro.
- Decreases LPS-mediated microglial activation in vivo.
- Down-regulates Aβ-mediated microglial activation in vivo.
Medchemexpress LLC PDGF-AA Rat P.past 50ug
PDGF-AA protein is a key growth factor that serves as an effective mitogen for mesenchymal cells coordinates embryonic development and affects cell proliferation migration survival and chemotaxis It plays an important role in alveolar septal formation gastrointestinal tract development interstitial cell maturation spermatogenesis oligodendrocyte development and myelination of the spinal cord and cerebellum PDGF-AA Protein Rat (P pastoris His) is the recombinant rat-derived PDGF-AA protein expressed by P pastoris with N-His labeled tag
Medchemexpress LLC IL-17A Mouse CHO 2ug
IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses IL-17A induces the production of antimicrobial peptides cytokines chemokines and matrix metalloproteinases[1][2] IL-17A Protein Mouse (CHO) is a recombinant mouse IL-17A protein and is expressed in CHO cells It consists of 133 amino acids (A26-A158)
Medchemexpress LLC P-Selectin Rat HEK 50ug
P-Selectin a Ca(2 )-dependent receptor on myeloid cells binds to neutrophils and monocytes via carbohydrates It interacts with SELPLG to enable rapid leukocyte rolling over vascular surfaces in early inflammation P-Selectin also interacts with SNX17 and promotes neutrophil adhesion and rolling requiring SELPLG s sialyl-Lewis X and tyrosine sulfation P-Selectin Protein Rat (HEK293 His) is the recombinant rat-derived P-Selectin protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC N-(4-(2-tert-butylphenyl)sulfonylphenyl)-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide | 877877-35-5 | 99.5% | 1 ML
TW-37 is a small-molecule BH3 mimetic that inhibits anti-apoptotic Bcl-2 family proteins and is used in apoptosis and oncology research. Supplied as a ready-to-use 10 mM solution in DMSO (1 mL), it is intended for research use only.
- Ready-to-use 10 mM solution in DMSO, 1 mL.
- Potent inhibition of Bcl-2 family proteins with Ki values: Mcl-1 260 nM; Bcl-2 290 nM; Bcl-xL 1,110 nM.
- Molecular formula: C33H35NO6S; molecular weight: 573.7 g·mol⁻1.
- High purity (99.5%) suitable for research applications.
- Intended for in vitro research use; not for clinical or therapeutic use.
Medchemexpress LLC E-Selectin/CD62E Hu 5ug
E-selectin/CD62E Protein a cell-surface glycoprotein crucially mediates immunoadhesion by interacting with SELPLG/PSGL1 for the adhesion of neutrophils to cytokine-activated endothelium It also potentially influences capillary morphogenesis and interacts with SELPLG/PSGL1 and PODXL2 through the sialyl Lewis X epitope independently of SELPLG sulfation E-Selectin/CD62E Protein Human (HEK293 His-Fc) is the recombinant human-derived E-Selectin/CD62E protein expressed by HEK293 with C-hFc C-His labeled tag
Medchemexpress LLC P-Selectin Rhesus M 10ug
P-Selectin Protein Rhesus Macaque (HEK293 His) is a member of the selectin family of cell adhesion molecules P-selectin (CD62P) has an N-terminal lectin domain an epidermal growth factor motif (generally) nine regulatory protein repeats a transmembrane section and a short intracytoplasmic tail P-selectin mediates leukocyte rolling on stimulated endothelial cells and heterotypic aggregation of activated platelets onto leukocytes P-selectin mediates heterotypic aggregation of activated platelets to cancer cells and adhesion of cancer cells to stimulated endothelial cells P-selectin glycoprotein ligand-1 (PSGL-1) is a major ligand for P-selectin[1][2][3] P-Selectin Protein Rhesus Macaque (HEK293 His) is the recombinant Rhesus Macaque-derived P-Selectin protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Zimelidine dihydrochloride | 60525-15-7 | 98.08% | 390.15 | 500 MG
Zimelidine dihydrochloride is a potent and selective inhibitor of serotonin 5-HT uptake and SERT, acting as an antidepressant.
- Potent and selective inhibitor of serotonin 5-HT uptake and SERT.
- Antidepressant.
eMolecules 89402-44-8 | 5-Bromo-2,3-difluoropyridine | Synthonix - Stock | MFCD06659525 | 193.979 | C5H2BrF2N | 97.000 | Fc1cc(Br)cnc1F | 25g | 525910663
5-Bromo-2,3-difluoropyridine | Synthonix - Stock | 89402-44-8 | MFCD06659525 | 193.979 | C5H2BrF2N | 97.000 | Fc1cc(Br)cnc1F | 25g | 525910663
![eMolecules 303752-38-7 | 3-(tert-butoxycarbonylamino)bicyclo[1.1.1]pentane-1-carboxylic acid | Pharmablock | MFCD09971715 | 227.260 | C11H17NO4 | 97.000 | CC(C)(C)OC(=O)NC12CC(C1)(C2)C(O)=O | 25g | 551211822](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000160757.jpg-250.jpg)
eMolecules 303752-38-7 | 3-(tert-butoxycarbonylamino)bicyclo[1.1.1]pentane-1-carboxylic acid | Pharmablock | MFCD09971715 | 227.260 | C11H17NO4 | 97.000 | CC(C)(C)OC(=O)NC12CC(C1)(C2)C(O)=O | 25g | 551211822
3-(tert-butoxycarbonylamino)bicyclo[1.1.1]pentane-1-carboxylic acid | Pharmablock | 303752-38-7 | MFCD09971715 | 227.260 | C11H17NO4 | 97.000 | CC(C)(C)OC(=O)NC12CC(C1)(C2)C(O)=O | 25g | 551211822
Medchemexpress LLC Isovanillin | 621-59-0 | 99.99% | 152.15 | 500 G
Isovanillin is identified as an aldehyde oxidase inhibitor and exhibits antispasmodic and antidiarrheal activities. It is not a substrate for aldehyde oxidase and is metabolized to isovanillic acid primarily by aldehyde dehydrogenase.
- Acts as an aldehyde oxidase inhibitor.
- Demonstrates relaxant effects on ileum contractions induced by 5-HT.
- Has antidiarrheal and anti-motility effects on the gastrointestinal tract.
- Potentially useful for research involving aldehyde oxidase inhibition.
- Offers a compound with known antispasmodic properties for relevant pharmacological studies.
- Provides a substance with documented antidiarrheal effects, suitable for gastrointestinal research.
Medchemexpress LLC P-Selectin Rhesus M 100ug
P-Selectin Protein Rhesus Macaque (HEK293 His) is a member of the selectin family of cell adhesion molecules P-selectin (CD62P) has an N-terminal lectin domain an epidermal growth factor motif (generally) nine regulatory protein repeats a transmembrane section and a short intracytoplasmic tail P-selectin mediates leukocyte rolling on stimulated endothelial cells and heterotypic aggregation of activated platelets onto leukocytes P-selectin mediates heterotypic aggregation of activated platelets to cancer cells and adhesion of cancer cells to stimulated endothelial cells P-selectin glycoprotein ligand-1 (PSGL-1) is a major ligand for P-selectin[1][2][3] P-Selectin Protein Rhesus Macaque (HEK293 His) is the recombinant Rhesus Macaque-derived P-Selectin protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC P-Selectin Human H 100ug
P-selectin is a Ca(2 )-dependent receptor on myeloid cells that critically binds to sialic acid-Lewis X on neutrophils and monocytes promoting the interaction between activated endothelial cells or platelets and leukocytes interaction This binding primarily to SELPLG/PSGL1 and PODXL2 is critical for rapid rolling of leukocytes during early inflammation P-Selectin Protein Human (HEK293 Fc) is the recombinant human-derived P-Selectin protein expressed by HEK293 with C-hFc labeled tag
Medchemexpress LLC Eteplirsen sodium | 91.2% | 10306 | 1 MG
Eteplirsen (AVI 4658) sodium is a synthetic antisense oligonucleotide that induces dystrophin production. It promotes exon 51 skipping in Duchenne muscular dystrophy patients and is used in Duchenne muscular dystrophy research.
- Induces dystrophin production.
- Promotes exon 51 skipping.
- Research use.
- High purity.