Parecoxib Sodium is a highly selective, orally active, and blood-brain barrier-permeable COX-2 inhibitor, functioning as a prodrug of Valdecoxib. It is a nonsteroidal anti-inflammatory agent (NSAID) that inhibits prostaglandin synthesis. It is used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions like osteoarthritis and rheumatoid arthritis.
- Target: COX-2
- Inhibits cell proliferation of GBM cells in a dose-dependent manner
- Decreases migratory ability of U343 cells
- Chronic administration exerts anxiolytic-like and memory-enhancing effects in mice
- Modulates synaptophysin expression in mice
- Appearance: Solid
- Color: White to off-white
- Shipping at room temperature in continental US
- Storage at 4°C, sealed, away from moisture
- In solvent storage at -80°C for 6 months or -20°C for 1 month