Carboxylic acids and derivatives
Apexbio Technology LLC Paroxetine maleate 64006-44-6 10mg
Paroxetine maleate (CAS 64006-44-6) is a selective serotonin reuptake inhibitor (SSRI) that blocks the reabsorption of serotonin into presynaptic neurons resulting in elevated synaptic serotonin levels and modulation of neurotransmission This compound is widely utilized in the investigation of serotonergic signaling related to anxiety disorders including generalized anxiety disorder post-traumatic stress disorder and premenstrual dysphoric disorder Additionally paroxetine maleate serves as a research tool in studies probing the neuropharmacological mechanisms of chronic headache and its prospective therapeutic interventions
Apexbio Technology LLC L-693,403 maleate 207455-21-8 50mg
L-693 403 maleate (CAS 207455-21-8) is a small molecule exhibiting high affinity and selectivity for sigma ( ) receptors By modulating receptor-mediated signaling pathways it influences neuronal signal transduction at the molecular level Preclinical studies indicate that L-693 403 maleate possesses analgesic properties likely through its regulatory effects on neural activity Owing to these pharmacological characteristics it is utilized in exploratory research on neurological disorders supporting its value as a tool compound in the investigation of neural modulation mechanisms
Medchemexpress LLC Indacaterol maleate | 753498-25-8 | 99.6% | C28H32N2O7 | 50 MG
Indacaterol maleate (Standard) is the analytical standard of Indacaterol maleate and is intended for research and analytical applications. It is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist that inhibits NF-κB activity in a β-arrestin2-dependent manner. This helps in preventing further lung damage and improving lung function in COPD.
- Can be used in cardiovascular disease research.
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Helps in preventing further lung damage and improving lung function in COPD.
Medchemexpress LLC (S)-Timolol maleate | 26921-17-5 | 99.8% | 432.49 | 200 MG
(S)-Timolol Maleate (L-714,465 Maleate) is a non-cardioselective hydrophilic β-adrenoceptor blocker. It is widely used as standard medication for intraocular pressure (glaucoma) by preventing the production of aqueous humor. It can also be used for hypertension, angina pectoris, and myocardial infarction.
- Non-cardioselective β-adadrenergic blocker
- Used for intraocular pressure (glaucoma)
- Prevents production of aqueous humor
- Suitable for hypertension
- Suitable for angina pectoris
- Suitable for myocardial infarction
Medchemexpress LLC Ciproxifan maleate | 184025-19-2 | C20H22N2O6 | 5 MG
Ciproxifan maleate is a potent, selective, orally bioavailable, and competitive antagonist of histamine H3-receptor, with an IC50 of 9.2 nM. It displays low apparent affinity at other receptor subtypes and can be used for the research of aging disorders and Alzheimer's disease.
- Purity: 99.68%
- Appearance: Solid
- Color: White to off-white
- Molecular weight: 386.40
- Solubility in DMSO: ≥ 100 mg/mL
- Solubility in H2O: 3.57 mg/mL
- Ships at room temperature in continental US
- Store at 4°C, sealed, away from moisture
- Store in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Flupirtine (maleate) | 75507-68-5 | 100.0% | 420.39 | 5 MG
Flupirtine (maleate) | 75507-68-5 | 100.0% | 420.39 | 5 MG
Apexbio Technology LLC Enalapril Maleate 76095-16-4 10mM (in 1mL DMSO)
Enalapril Maleate (CAS 76095-16-4) is the maleate salt of enalapril a prodrug metabolized in vivo into its active metabolite enalaprilat It exerts its pharmacological activity through inhibition of angiotensin-converting enzyme (ACE) thereby preventing conversion of angiotensin I into angiotensin II This action reduces aldosterone secretion and attenuates vasoconstriction Enalapril Maleate is widely utilized in basic and clinical cardiovascular research particularly for examining the renin-angiotensin system (RAS) and associated cardiovascular pathophysiology
Cayman Chemical Thioperamide (maleate), Purity: ≥98%, CAS: 148440-81-7, 25 mg
A histamine H3 receptor antagonist (Ki = 4.3 nM); selective for the histamine H3 receptor over histamine H1 and H2 receptors (Kis = >10,000 nM for both) and a panel of 36 other receptors and ion channels; has anticonvulsant activity, reverses immepip-induced antinociception, and promotes wakefulness in rats; decreases cognitive impairments in APP/PS1 mice
Apexbio Technology LLC CIPROXIFAN-MALEATE-50MG
Ciproxifan maleate (CAS No 184025-19-2) is a potent histamine H3 receptor antagonist primarily studied in the field of neuropharmacology Originating from synthetic chemical research it functions by selectively blocking H3 receptors which modulate the release of histamine and other neurotransmitters in the brain influencing cognition and wakefulness In vitro studies show activity in the nanomolar to low micromolar range demonstrating its high affinity and specificity for the target receptor It is commonly used in cell models to explore neurological pathways and in animal studies to assess cognitive function and potential therapeutic effects for disorders such as narcolepsy and Alzheimer s disease Ciproxifan maleate is also utilized in drug screening contexts to identify compounds affecting histamine pathways Experimental concentrations typically depend on the specific research design allowing flexibility to accommodate diverse study parameters
eMolecules 2396-80-7 | ChemScene | Methyl 5-hexenoate | 5g | 447993418 | CS-0015919 | MFCD00671538 | 128.171 | C7H12O2
ChemScene | 4-(Dodecyloxy)-[11-biphenyl]-4-carbonitrile | 1g | 632338738 | CS-0183038 | 57125-50-5 | MFCD01941019 | 363.545 | C25H33NO
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC Dimethyl fumarate-d6 | 66487-95-4 | 99.0% | 150.16 | 5 MG
Dimethyl fumarate-d6 is a deuterium labeled Dimethyl fumarate. Dimethyl fumarate is a nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator and induces upregulation of antioxidant gene expression. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Used as a tracer and internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Activates the nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway.
- Upregulates antioxidant gene expression.
Medchemexpress LLC Perhexiline (maleate) | 6724-53-4 | 100.0% | 1 ML
Perhexiline maleate is an orally active CPT1 and CPT2 inhibitor that reduces fatty acid metabolism. It induces mitochondrial dysfunction and apoptosis in hepatic cells. It can cross the blood-brain barrier (BBB) and exhibits anti-tumor activity. Perhexiline maleate is used in the research of cancers and cardiovascular diseases like angina.
- Orally active CPT1 and CPT2 inhibitor
- Reduces fatty acid metabolism
- Induces mitochondrial dysfunction and apoptosis in hepatic cells
- Can cross the blood-brain barrier (BBB)
- Shows anti-tumor activity
- Useful in research for cancers and cardiovascular diseases like angina
TARGETMOL CHEMICALS INC --DIZOCILPINE MALEATE 50MG
Also available in 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. (-)-Dizocilpine maleate ((-)-MK 801 (Maleate)) is a potent selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes. purity: 99%
eMolecules 922-67-8 | Methyl propiolate | Ambeed | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 10g | 552720843
Methyl propiolate | Ambeed | 922-67-8 | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 10g | 552720843