Carboxylic acids and derivatives
Apexbio Technology LLC Cefoxitin (sodium salt) 33564-30-6 500mg
Cefoxitin sodium salt (CAS 33564-30-6) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit PBPs thereby interfering with bacterial cell wall synthesis and peptidoglycan cross-linking Cefoxitin sodium salt exerts its biological activity primarily through inhibition of cell wall synthesis by binding to PBPs In in vitro enzymatic assays Cefoxitin sodium salt demonstrates inhibitory activity against various gram-positive and gram-negative bacteria with previously reported IC50 values in the low micromolar range due to its resistance to certain beta-lactamases including AmpC -lactamases Based on these pharmacological properties Cefoxitin sodium salt holds research potential in investigations of bacterial resistance mechanisms antimicrobial sensitivity profiling and beta-lactamase enzyme kinetics
Medchemexpress LLC Boc-NH-PEG2-CH2COOH | 108466-89-3 | 263.29 | 100 G
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are designed with two different ligands connected by a linker; one binds to an E3 ubiquitin ligase and the other to the target protein, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- Peg-based protac linker
- Used in the synthesis of protacs
- Enables selective degradation of target proteins
Strem, An Ascensus Company CAS# 51805-45-9. 25g. Tris(2-carboxyethyl)phosphine, hydrochloride, 99% TCEP. MFCD00145469
CAS# 51805-45-9. 25g. Tris(2-carboxyethyl)phosphine, hydrochloride, 99% TCEP. MFCD00145469. Molecular Weight: 286.65. Molecular Formula: (HOOCCH2CH2)3PH+Clae. Color/form: white xtl. Strem# 15-7400. http://www.strem.com/catalog/v/15-7400/
eMolecules 74444-77-2 | 2-AMINOTETRALIN-2-CARBOXYLIC ACID | AstaTech | MFCD00800504 | 191.230 | C11H13NO2 | 95.000 | NC1(CCc2ccccc2C1)C(O)=O | 1g | 589772675
2-AMINOTETRALIN-2-CARBOXYLIC ACID | AstaTech | 74444-77-2 | MFCD00800504 | 191.230 | C11H13NO2 | 95.000 | NC1(CCc2ccccc2C1)C(O)=O | 1g | 589772675
Apexbio Technology LLC Cefoxitin (sodium salt) 33564-30-6 1g
Cefoxitin sodium salt (CAS 33564-30-6) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit PBPs thereby interfering with bacterial cell wall synthesis and peptidoglycan cross-linking Cefoxitin sodium salt exerts its biological activity primarily through inhibition of cell wall synthesis by binding to PBPs In in vitro enzymatic assays Cefoxitin sodium salt demonstrates inhibitory activity against various gram-positive and gram-negative bacteria with previously reported IC50 values in the low micromolar range due to its resistance to certain beta-lactamases including AmpC -lactamases Based on these pharmacological properties Cefoxitin sodium salt holds research potential in investigations of bacterial resistance mechanisms antimicrobial sensitivity profiling and beta-lactamase enzyme kinetics
Apexbio Technology LLC AVE 0991 sodium salt 306288-04-0 50mg
AVE 0991 sodium salt (CAS 306288-04-0) is a synthetic non-peptide agonist of the angiotensin-(1-7) receptor Mas Acting as a functional mimic of angiotensin-(1-7) AVE 0991 competitively binds to endothelial cell membranes with an IC50 of 21 35 nM in bovine aortic endothelial cells In vitro treatment with AVE 0991 promotes nitric oxide release to levels significantly greater than angiotensin-(1-7) In vivo AVE 0991 reduces urine volume and increases urine osmolality in mice effects reversed by angiotensin II antagonists indicating receptor specificity It also inhibits atherogenesis in ApoE knockout mice supporting its application in cardiovascular and renal research
Apexbio Technology LLC Mosapride Citrate 112885-42-4 10mM (in 1mL DMSO)
Mosapride Citrate (CAS 112885-42-4) is a small molecule that functions as a selective agonist of the 5-hydroxytryptamine 4 (5-HT ) receptor and an antagonist of the 5-HT receptor with negligible activity at dopaminergic D adrenergic and as well as 5-HT and 5-HT receptors By modulating serotonin receptor activity it enhances gastrointestinal motility and accelerates gastric emptying Mosapride Citrate is widely used in research investigating serotonergic signaling pathways gut motility regulation and potential therapeutic approaches for gastrointestinal disorders
Medchemexpress LLC Subasumstat | 1858276-04-6 | 578.10 | 100 MG
Subasumstat (TAK-981) is a first-in-class and selective inhibitor of the SUMOylation enzymatic cascade, demonstrating potential immune-activating and antineoplastic activities. It increases the production of type 1 IFN, enhancing type 1 IFN-mediated signaling, activating innate effector cells, and improving antitumor innate immune responses. A single subcutaneous injection induces activation of dendritic cells.
- First-in-class selective inhibitor of SUMOylation enzymatic cascade
- Potential immune-activating activities
- Potential antineoplastic activities
- Increases production of type 1 IFN
- Enhances antitumor innate immune responses
- Activates innate effector cells
- Induces activation of dendritic cells
Crescent Chemical Co Inc CITRIC ACID-NA3-SALT-2H2O
Citric acid-Na3-salt-2H2O analytical grade, Ph. Eur. Size - 1KG Storage Conditions - +15 °C TO +30 °C Catalog Number - 38642.02 CAS 1545801
Medchemexpress LLC Ciproxifan maleate | 184025-19-2 | C20H22N2O6 | 5 MG
Ciproxifan maleate is a potent, selective, orally bioavailable, and competitive antagonist of histamine H3-receptor, with an IC50 of 9.2 nM. It displays low apparent affinity at other receptor subtypes and can be used for the research of aging disorders and Alzheimer's disease.
- Purity: 99.68%
- Appearance: Solid
- Color: White to off-white
- Molecular weight: 386.40
- Solubility in DMSO: ≥ 100 mg/mL
- Solubility in H2O: 3.57 mg/mL
- Ships at room temperature in continental US
- Store at 4°C, sealed, away from moisture
- Store in solvent at -80°C for 6 months or -20°C for 1 month