Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Pacritinib citrate is a potent inhibitor of both wild-type JAK2 (IC50=23 nM) and JAK2V617F mutant (IC50=19 nM). It also inhibits FLT3 (IC50=22 nM) and its mutant FLT3D835Y (IC50=6 nM). Pacritinib citrate can be used for the research of acute myeloid leukemia (AML) and myelofibrosis (MF).
Potent inhibitor of wild-type JAK2 (IC50=23 nM)
Potent inhibitor of JAK2V617F mutant (IC50=19 nM)
Inhibits FLT3 (IC50=22 nM)
Inhibits FLT3D835Y mutant (IC50=6 nM)
Can be used for the research of acute myeloid leukemia (AML)
Can be used for the research of myelofibrosis (MF)
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Boc-NH-PEG6-CH2COOH is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. This compound is for research use only and not intended for patient use. It helps exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Molecular weight: 439.50
Appearance: Colorless to light yellow liquid
Density: 1.134±0.06 g/cm3
Shipping at room temperature (continental US)
Storage (pure form): -20°C for 3 years or 4°C for 2 years
Storage (in solvent): -80°C for 6 months or -20°C for 1 month
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Enclomiphene citrate is a research-grade, non-steroidal estrogen receptor antagonist supplied as a solid or as a ready-to-use 10 mM solution in DMSO for in vitro and in vivo studies.
High purity typically 99.93%.
Available as a 10 mM solution (1 mL) in DMSO or as mg-scale solids.
Used for studies of ovarian dysfunction, testosterone deficiency, and male hypogonadism.
Molecular weight 598.09, formula C32H36ClNO8, CAS 7599-79-3.
Store powder at 4°C; stock solutions at -80°C (6 months) or -20°C (1 month).
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker with a tosyl cap and a three-unit polyethylene glycol spacer terminating in a carboxylic acid. It is designed for use in the synthesis of PROTACs and other bifunctional molecules where a short, flexible, polar spacer and a carboxyl functional handle are required.
Tosyl-capped PEG3 spacer ending in a carboxylic acid for conjugation.
Provides a short, flexible, hydrophilic linker suitable for cellular applications.
Terminal carboxyl group enables amide or ester coupling chemistries.
Compatible with solid-phase and solution-phase synthetic workflows.
Supplied in research-scale quantities for medicinal chemistry and PROTAC development.
Molecular formula C15H22O8S, molecular weight ≈362.40 g/mol.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Gefapixant citrate is the citrate salt of gefapixant, an orally active P2X3 receptor antagonist used in research on chronic cough and pain-related indications. Supplied as a research-grade solid with high purity, it is suitable for in vitro and in vivo studies and is accompanied by technical documentation for analytical use.
Potent P2X3 receptor antagonist with low-nanomolar activity.
High purity suitable for research applications.
Available in small solid quantities for dose-ranging studies.
Includes datasheet, certificate of analysis, and safety data sheet documentation.
Soluble stock solutions offered for convenient preparation.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
(E/Z)-Zotiraciclib citrate is a potent inhibitor targeting CDK2, JAK2, and FLT3. This compound is supplied as a solid, appearing off-white to light yellow, and is intended for research use only.
Potent CDK2, JAK2, and FLT3 inhibitor
High purity: 99.83%
Molecular weight: 564.59
Store at 4°C, sealed, away from moisture
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Boc-NH-PEG1-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Molecular weight: 219.23
Appearance: Solid-liquid mixture
Color: Colorless to light yellow
SMILES: O=C(O)COCCNC(OC(C)(C)C)=O
Storage (pure form): -20°C for 3 years, 4°C for 2 years
Storage (in solvent): -80°C for 6 months, -20°C for 1 month
Solubility (in vitro): DMSO at 100 mg/mL (456.14 mM)
Solubility (in vivo): Protocols available for DMSO, PEG300, Tween-80, Saline, SBE-β-CD, and Corn Oil
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Bromo-PEG1-CH2COOH is a PROTAC linker, designed for use in the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins, by connecting an E3 ubiquitin ligase ligand to a target protein ligand.
Used as a PROTAC linker
Designed for PROTAC synthesis
Contains two ligands connected by a linker
One ligand targets an E3 ubiquitin ligase
Other ligand targets a protein
Exploits the ubiquitin-proteasome system
Enables selective degradation of target proteins
For research use only
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More