Carboxylic acids and derivatives
eMolecules 2306245-86-1 | (3R)-1-(2-chloroethyl)pyrrolidin-3-ol hydrochloride | 1g
ChemScene | 6-Methyl-3H-13-benzothiazol-2-one | 100mg | 569144678 | CS-0061341 | 53827-53-5 | MFCD08689970 | 165.210 | C8H7NOS
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Selleck Chemical LLC L-685 458
L-685 458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM
Apexbio Technology LLC CAL-101 (Idelalisib, GS-1101) 870281-82-6 100mg
CAL-101 (Idelalisib GS-1101 CAS 870281-82-6) is a selective inhibitor targeting the p110 isoform of phosphatidylinositol 3-kinase (PI3K) an enzyme involved in signaling pathways critical for proliferation and survival of malignant B cells By inhibiting PI3K p110 CAL-101 reduces PI3K-mediated phosphorylation of Akt and other downstream factors leading to enhanced PARP cleavage and caspase activation ultimately inducing apoptosis in malignant B cells CAL-101 has been demonstrated to counteract survival signals initiated by molecules such as CD40 ligand (CD40L) TNF- and fibronectin This agent is valuable in investigating B-cell malignancies