Acylaminobenzoic acid and derivatives
Sigma Aldrich 2-Phenylethenesulfonyl fluoride
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 4-Acetamidobenzoic Acid
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Medchemexpress LLC Chloro-2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-α-D-glucopyranose | 3068-34-6 | 98.0% | 365.76 | 500 MG
Chloro 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-α-D-glucopyranose is a biochemical reagent used in glycobiology research. Glycobiology involves the study of the structure, synthesis, biology, and evolution of sugars, encompassing carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is relevant to basic research, biomedicine, and biotechnology.
- Used in glycobiology research.
- Relevant to carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems.
- Closely related to basic research, biomedicine, and biotechnology.
- Available with a purity of 98.0%.
Medchemexpress LLC Chloro 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-α-D-glucopyranose | 3068-34-6 | 98.0% | 365.76 | 1 G
Chloro 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-α-D-glucopyranose is a biochemical reagent utilized in glycobiology research. This field explores the structure, synthesis, biology, and evolution of sugars, encompassing carbohydrate chemistry, the enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans within biological systems. It is relevant to basic research, biomedicine, and biotechnology.
- Molecular weight: 365.76
- Formula: C14H20ClNO8
- CAS no.: 3068-34-6
- Appearance: Solid
- Color: White to off-white
- Purity: 98.0%
Medchemexpress LLC 4-acetamido-5-chloro-2-methoxybenzoic acid | 24201-13-6 | MFCD07783714 | 99.4% | 243.65 | C10H10ClNO4 | 1 G
4-Acetamido-5-chloro-2-methoxybenzoic acid is a benzoic-acid derivative used as a drug intermediate and analytical impurity reference in medicinal chemistry and process development. It is supplied for research use where high chemical purity and traceable analytical documentation are required.
- High purity (99.39% by LCMS).
- Molecular formula C10H10ClNO4.
- Molecular weight 243.65 g·mol⁻¹.
- Suitable as a drug intermediate and impurity reference standard.
- Supplied with certificate of analysis and safety data sheet for traceability.
Medchemexpress LLC 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galactopyranosyl chloride | 41355-44-6 | MFCD00047513 | 97.0% | 365.76 g/mol | C14H20ClNO8 | 5 G
2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galactopyranosyl chloride is an acetyl-protected amino-sugar glycosyl chloride used as a glycosyl donor in carbohydrate chemistry and glycobiology research. It is employed as an intermediate in the synthesis of protected glycosides and for method development in glycosylation and analytical workflows.
- Acetyl-protected glycosyl donor suitable for glycosylation reactions.
- Contains 2-acetamido functionality for amino-sugar derivatization.
- Stable protected form for storage and handling in synthetic workflows.
- Compatible with common glycosylation promoters and catalysts.
- Available in small laboratory pack sizes for research use.
Medchemexpress LLC 4-acetamido-5-chloro-2-methoxybenzoic acid | 24201-13-6 | MFCD07783714 | 99.4% | 243.65 g/mol | C10H10ClNO4 | 500 MG
4-Acetamido-5-chloro-2-methoxybenzoic acid is a chemical intermediate used in pharmaceutical research and synthesis; it is also identified as Metoclopramide Impurity 12 and is supplied as a white to off-white solid suitable for medicinal chemistry applications.
- High purity: 99.4%.
- Molecular formula: C10H10ClNO4; molecular weight: 243.65 g/mol.
- Appearance: white to off-white solid.
- Storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); in solvent at -80°C (6 months) or -20°C (1 month).
- Packaging: available in sizes from 100 mg to 10 g.
Medchemexpress LLC 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galactopyranosyl chloride | 41355-44-6 | MFCD00047513 | >98.0% | 365.76 g/mol | C14H20ClNO8 | 500 MG
2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galactopyranosyl chloride is an acetyl-protected glycosyl chloride used as a glycosyl donor and synthetic intermediate in carbohydrate chemistry and glycobiology research. It is employed to assemble oligosaccharides and glycan analogues via glycosylation reactions and is handled under standard laboratory safety procedures.
- Acetyl-protected glycosyl donor suitable for glycosylation reactions.
- Facilitates synthesis of oligosaccharides and glycan analogues.
- Reactive anomeric chloride enables coupling under standard activation conditions.
- Compatible with common protecting group strategies in carbohydrate synthesis.
- Supplied for research use; handle with appropriate PPE and protocols.
![Medchemexpress LLC 3-Quinolineethanol, 6-bromo-α-(2,6-dimethoxy-4-pyridinyl)-α-[2-(dimethylamino)ethyl] | 2252316-16-6 | 99.7% | 614.50 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000438958-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC 3-Quinolineethanol, 6-bromo-α-(2,6-dimethoxy-4-pyridinyl)-α-[2-(dimethylamino)ethyl] | 2252316-16-6 | 99.7% | 614.50 | 1 ML
TBAJ-587 is a potent anti-tuberculosis agent that inhibits the growth of M.tb strain H37Rv with MIC90s of 0.006 and <0.02 μg/mL in MABA and LORA assays, respectively. It minimally inhibits the hERG channel, attenuating inhibition of the cardiac potassium channel protein coded by hERG, which is crucial for cardiac repolarization.
- Potent anti-tuberculosis agent
- Inhibits M.tb strain H37Rv growth
- Minimally inhibits hERG channel
- Attenuates inhibition of cardiac potassium channel protein
- Analog of Bedaquiline with more potent anti-tubercular activity and greatly attenuated hERG blockade
![Medchemexpress LLC 3-Quinolineethanol, 6-bromo-α-(2,6-dimethoxy-4-pyridinyl)-α-[2-(dimethylamino)ethyl]-β-(2-fluoro-3-methoxyphenyl)-2-methoxy- | 2252316-16-6 | 99.7% | 614.50 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000439893-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC 3-Quinolineethanol, 6-bromo-α-(2,6-dimethoxy-4-pyridinyl)-α-[2-(dimethylamino)ethyl]-β-(2-fluoro-3-methoxyphenyl)-2-methoxy- | 2252316-16-6 | 99.7% | 614.50 | 25 MG
TBAJ-587 is a potent anti-tuberculosis agent, an analogue of Bedaquiline, demonstrating more potent anti-tubercular activity. It inhibits *M.tb* strain H37Rv growth with MIC90s of 0.006 and <0.02 μg/mL in MABA and LORA assays, respectively. A key feature of TBAJ-587 is its greatly attenuated inhibition of the cardiac potassium channel protein hERG compared to Bedaquiline, with an IC50 of 13 μM for hERG channel inhibition, thus reducing cardiac liability.
- Potent anti-tuberculosis agent.
- Inhibits *M.tb* strain H37Rv growth.
- Minimally inhibits the hERG channel.
- Reduces cardiac liability compared to Bedaquiline.
Apexbio Technology LLC PF-05212384 (PKI-587) 1197160-78-3 25mg
PF-05212384 (PKI-587) is a dual inhibitor targeting both phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) It exhibits potent inhibitory activity targeting PI3K isoforms with IC50 values of 0 4 nM 6 nM 8 nM and 6 nM respectively as well as mTOR at 1 4 nM Furthermore PF-05212384 effectively suppresses mutant PI3K forms including the H1047R and E545K mutations In cell-based assays this compound inhibits PI3K/mTOR signaling pathways evidenced by decreased phosphorylation of downstream proteins Akt GSK3 eNOS and PRAS40 PF-05212384 has demonstrated anti-tumor effects in various xenograft tumor models thus serving as a useful tool molecule for investigating PI3K/mTOR pathway functions and related oncology studies
C 646, Tocris Bioscience™
CAS: 328968-36-1 Molecular Formula: C24H19N3O6 Molecular Weight (g/mol): 445.43 MDL Number: MFCD01784780 InChI Key: HEKJYZZSCQBJGB-UHFFFAOYSA-N Synonym: 4-4-5-4,5-dimethyl-2-nitrophenyl furan-2-yl methylidene-3-methyl-5-oxopyrazol-1-yl benzoic acid PubChem CID: 2871948 IUPAC Name: 4-(4-{[5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl]methylidene}-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid SMILES: CC1=NN(C(=O)C1=CC1=CC=C(O1)C1=CC(C)=C(C)C=C1[N+]([O-])=O)C1=CC=C(C=C1)C(O)=O