Aminobenzoic acids and derivatives
Anatrace ETHYL DIMETHYL AMMONIO PROPANE SULFONATE | 160255-06-1 | 195.28 g/mol | 25G
ETHYL DIMETHYL AMMONIO PROPANE SULFONATE | 160255-06-1 | 195.28 g/mol | 25G
Medchemexpress LLC 7-chlorokynurenic acid sodium salt | 1263094-00-3 | MFCD12195840 | >99.0% | 245.59 | C10H5ClNNaO3 | 50 MG
7-Chlorokynurenic acid sodium salt is the sodium salt form of a potent and selective antagonist of the glycine co-agonist site on the NMDA receptor. Supplied for research use, the compound is intended for biochemical and pharmacological studies where selective NMDA modulation and water-soluble formulations are required.
- Potent and selective antagonist of the NMDA glycine site.
- Sodium salt form with improved aqueous solubility.
- High purity suitable for research applications.
- Soluble in water and DMSO, facilitating preparation of stock solutions.
- Recommended short-term storage at 4°C under inert atmosphere; long-term storage in solvent at -80°C.
Medchemexpress LLC N-acetyl-L-valyl-L-alpha-glutamyl-L-isoleucyl-L-aspart-1-al | 00-00-0 | MFCD01318861 | 99.8% | 614.57 g/mol | C24H37F3N4O11 | 10 MG
Ac-VEID-CHO TFA is a peptide-derived reversible caspase inhibitor for biochemical research, commonly used to probe caspase activity and mechanisms relevant to neurodegeneration. It is formulated as a salt suitable for in vitro enzymatic assays and VEIDase activity studies.
- Peptide-derived reversible caspase inhibitor.
- Biochemical IC50 values: caspase-3 13.6 nM, caspase-6 16.2 nM, caspase-7 162.1 nM.
- High purity (≈99.8%).
- White to off-white solid, soluble in water with sonication and warming.
- Limited cellular accumulation; low activity in intact cell assays (>100 μM).
- Recommended storage: sealed, -80°C for long term, -20°C for up to 1 year.
Apexbio Technology LLC Nafamostat 81525-10-2 50mg
Nafamostat (CAS 81525-10-2) is a small-molecule inhibitor targeting a broad spectrum of serine proteases including thrombin plasmin kallikrein and human trypsin It is designed to block protease-mediated hydrolysis reactions thereby regulating coagulation pathways and inflammation-related protease activity Nafamostat exerts its biological activity primarily through reversible binding to protease active sites inhibiting their enzymatic functions In biochemical assays Nafamostat demonstrates potent inhibitory activity with an IC50 value of approximately 1 10 nM against human trypsin Based on these pharmacological properties Nafamostat holds research potential in coagulation pathway studies inflammation-related protease research pancreatitis modeling and mechanistic investigations of blood coagulation disorders and inflammatory responses
Selleck Chemical LLC Schisandrin A S3822-5mg
Schisandrin A (Sch A Deoxyschizandrin Wuweizisu A) is an active component of Schisandrae Fructus with liver-protective antitumor and antioxidant activities It is an agonist of the adiponectin receptor 2 (AdipoR2) with the IC50 value of 3 5 M
Medchemexpress LLC (R)-2-amino-3-(m-tolyl)propanoic acid | 114926-39-5 | MFCD05227937 | 97.0% | 179.22 g·mol-1 | C10H13NO2 | 25 G
(R)-2-Amino-3-(m-tolyl)propanoic acid is the R-enantiomer of a phenylalanine derivative bearing a meta-methyl (m-tolyl) substituent. Supplied as a solid research reagent (CAS 114926-39-5, MW 179.22 g·mol-1), it is used as an enantiomerically defined amino-acid building block in synthetic chemistry and biochemical studies.
- Enantiomerically defined R-configuration suitable for stereospecific synthesis.
- Useful as a synthetic building block for peptide and small-molecule synthesis.
- Suitable for biochemical and pharmacological research applications.
- Off-white to white solid form for easy handling and storage.
- Typical purity around 97.0% as provided by the supplier.
Apexbio Technology LLC 3-aminobenzamide 3544-24-9 10mM (in 1mL DMSO)
3-Aminobenzamide (CAS 3544-24-9) is a potent inhibitor of poly(ADP-ribose) polymerase (PARP) exhibiting an IC50 of approximately 50 nM in CHO cell assays At concentrations above 1 M it suppresses over 95% of PARP activity without notable cytotoxicity In cellular models 3-aminobenzamide mitigates oxidative stress-induced endothelial dysfunction by enhancing acetylcholine-induced nitric oxide-mediated vasodilation following hydrogen peroxide exposure In vivo it has been shown to attenuate diabetic nephropathy in Leprdb/db mice by reducing albuminuria glomerular mesangial expansion and podocyte loss 3-Aminobenzamide serves as a valuable tool for PARP-related research in oxidative injury and metabolic disease models
Apexbio Technology LLC Mulberroside A 102841-42-9 20mg
Mulberroside A (CAS 102841-42-9) is a natural phenolic compound isolated from species of the Moraceae family particularly Morus genus It is known to exert biological effects by modulating cellular oxidative stress and inhibiting melanin biosynthesis with studies indicating its regulatory role in tyrosinase activity Mulberroside A has been investigated for its antioxidant and anti-inflammatory properties as well as its potential to suppress melanogenesis in cellular models These activities make it a suitable molecule for research into dermatological disorders oxidative stress-related conditions and the mechanistic study of natural product-based therapeutics
Medchemexpress LLC Golgicide A-2 | 1394285-50-7 | 99.5% | 284.30 g/mol | C17H14F2N2 | 1 ML
Golgicide A-2 is a synthetic enantiomeric derivative of Golgicide A that selectively inhibits cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEFs). It is used in research on Golgi function, viral replication, and insecticidal activity. The compound is supplied as a ready-to-use solution for laboratory experiments.
- 10 mM in DMSO, 1 mL vial.
- Selective inhibitor of cis-Golgi Arf guanine nucleotide exchange factors (ArfGEFs).
- High purity (99.5%).
- Molecular formula C17H14F2N2 and molecular weight 284.30 g/mol.
- CAS number 1394285-50-7.
- Suitable for studies of viral replication, Golgi function, and insecticidal effects.
Medchemexpress LLC Nigericin sodium salt | 28643-80-3 | MFCD30377206 | 99.4% | 746.94 g/mol | C40H67NaO11 | 50 MG
Nigericin sodium salt is an ionophore antibiotic used as an NLRP3 inflammasome activator in cell biology and pharmacology research. It facilitates transmembrane K+/H+ exchange to alter intracellular pH and is commonly used to trigger inflammasome activation, investigate ion transport, and study apoptosis and cancer-related signaling. Supplied as a solid with documented solubility and storage guidance for experimental use.
- Activates the NLRP3 inflammasome in cell-based assays.
- Acts as an ionophore facilitating K+/H+ exchange across membranes.
- Enables modulation of intracellular pH for mechanistic studies.
- Compatible with in vitro and in vivo formulation protocols provided by the supplier.
- Provided as a white to off-white solid with high analytical purity.
- Stable when stored under recommended sealed, low-temperature conditions.