Anilides
Medchemexpress LLC Leflunomide | 75706-12-6 | 99.8% | C12H9F3N2O2 | 1 ML
Leflunomide is a pyrimidine synthesis inhibitor that acts by inhibiting dihydroorotate dehydrogenase (DHODH), functioning as a disease-modifying antirheumatic agent. It is an immunomodulatory drug that prevents the expansion of activated and autoimmune lymphocytes by interfering with cell cycle progression due to inadequate rUMP production and by utilizing mechanisms involving p53. This product is for research use only.
- Inhibits dihydroorotate dehydrogenase (DHODH)
- Functions as a disease-modifying antirheumatic agent
- Inhibits proliferation of mononuclear and T-cells
- Inhibits several protein tyrosine kinases
- Prevents expansion of activated and autoimmune lymphocytes
Cayman Chemical Leflunomide, Purity: ≥98%, CAS: 75706-12-6, 25 mg
A prodrug form of A-771726; inhibits de novo pyrimidine synthesis to regulate T lymphocyte progression through the cell cycle; inhibits proliferation and activation of T cells at 25 and 100 µM, respectively, for naïve and memory CD4+ T cells; reduces and prevents inflammation in a proteoglycan-induced mouse model of rheumatoid arthritis at 35 mg/kg per day
Cayman Chemical Leflunomide, Purity: ≥98%, CAS: 75706-12-6, 500 mg
A prodrug form of A-771726; inhibits de novo pyrimidine synthesis to regulate T lymphocyte progression through the cell cycle; inhibits proliferation and activation of T cells at 25 and 100 µM, respectively, for naïve and memory CD4+ T cells; reduces and prevents inflammation in a proteoglycan-induced mouse model of rheumatoid arthritis at 35 mg/kg per day
4-Acetylaminobenzaldehyde thiosemicarbazone, 98%, Thermo Scientific™
CAS: 104-06-3 Molecular Formula: C10H12N4OS Molecular Weight (g/mol): 236.293 MDL Number: MFCD00022157 InChI Key: SRVJKTDHMYAMHA-WUXMJOGZSA-N Synonym: thioacetazone,thiacetazone,amithiozone,ambathizon,benzothiozane,conteben,benzothiozon,benthiozone,parazone,thioacetazon PubChem CID: 9568512 IUPAC Name: N-[4-[(E)-(carbamothioylhydrazinylidene)methyl]phenyl]acetamide SMILES: CC(=O)NC1=CC=C(C=C1)C=NNC(=S)N
AM 580
CAS: 102121-60-8 Molecular Formula: C22H25NO3 Molecular Weight (g/mol): 351.45 MDL Number: MFCD00673916 InChI Key: SZWKGOZKRMMLAJ-UHFFFAOYSA-N Synonym: unii-vz5s5g9zfz,4-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl carbonyl amino benzoic acid,vz5s5g9zfz,chembl69367,4-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carboxamido benzoic acid,benzoic acid,4-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl carbonyl amino,4-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl carbonyl aminobenzoic acid,4-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl carboxamido benzoic acid,4-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl carbonyl amino benzoic acid,benzoic acid, 4-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl carbonyl amino PubChem CID: 2126 ChEBI: CHEBI:64210 IUPAC Name: 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbonyl)amino]benzoic acid SMILES: CC1(C)CCC(C)(C)C2=CC(=CC=C12)C(=O)NC1=CC=C(C=C1)C(O)=O
MP Biomedicals, Inc 2-Methyltetrahydroharmol HCl, MP Biomedicals
CAS: 7128-79-2 Molecular Formula: C20H17NO4 Molecular Weight (g/mol): 335.359 InChI Key: RKCVQLUEWCVWTN-UHFFFAOYSA-N Synonym: 2-n-o-methoxyphenyl carbamoyl-3-naphthyl acetate,3-2-methoxyphenyl carbamoyl naphthalen-2-yl acetate,naphthol-as-ol-acetat,naphthol as-ol acetate,3-acetoxy-2'-methoxy-2-naphthanilide,3-n-2-methoxyphenyl carbamoyl-2-naphthyl acetate,3-acetyloxy-n-2-methoxyphenyl-2-naphthalenecarboxamide,3-2-methoxyphenyl carbamoyl naphthalen-2-yl ethanoate PubChem CID: 81552 IUPAC Name: [3-[(2-methoxyphenyl)carbamoyl]naphthalen-2-yl] acetate SMILES: CC(=O)OC1=CC2=CC=CC=C2C=C1C(=O)NC3=CC=CC=C3OC
3'-Aminoacetanilide, 97%, Thermo Scientific™
CAS: 102-28-3 Molecular Formula: C8H10N2O Molecular Weight (g/mol): 150.18 MDL Number: MFCD00025229 InChI Key: PEMGGJDINLGTON-UHFFFAOYSA-N Synonym: n-3-aminophenyl acetamide,3'-aminoacetanilide,3-aminoacetanilide,m-aminoacetanilide,acetamide, n-3-aminophenyl,3-acetamidoaniline,m-acetaminoaniline,m-acetylamino aniline,3-aminoacetanilid,3-amino-n-acetylaniline PubChem CID: 7604 IUPAC Name: N-(3-aminophenyl)acetamide SMILES: CC(=O)NC1=CC=CC(N)=C1
2',4'-Dimethylacetanilide, 98%, Thermo Scientific™
CAS: 2050-43-3 Molecular Formula: C10H13NO Molecular Weight (g/mol): 163.22 MDL Number: MFCD00026125 InChI Key: PJEIIBXJUDOMAN-UHFFFAOYSA-N Synonym: n-2,4-dimethylphenyl acetamide,2',4'-dimethylacetanilide,2,4-dimethylacetanilide,4-acetamido-m-xylene,2',4'-acetoxylidine,2',4'-acetoxylidide,acetamide, n-2,4-dimethylphenyl,acetanilide, 2',4'-dimethyl,n-acetyl-2,4-xylidine,unii-3u0w52hz1h PubChem CID: 16303 IUPAC Name: N-(2,4-dimethylphenyl)acetamide SMILES: CC1=CC(=C(C=C1)NC(=O)C)C
4'-Methoxyacetanilide, 99+%, Thermo Scientific™
CAS: 51-66-1 Molecular Formula: C9H11NO2 Molecular Weight (g/mol): 165.192 InChI Key: XVAIDCNLVLTVFM-UHFFFAOYSA-N Synonym: n-4-methoxyphenyl acetamide,4'-methoxyacetanilide,p-methoxyacetanilide,p-acetanisidide,p-acetanisidine,methacetin,4-methoxyacetanilide,aceto-p-anisidide,n-acetyl-p-anisidine,acetamide, n-4-methoxyphenyl PubChem CID: 5827 IUPAC Name: N-(4-methoxyphenyl)acetamide SMILES: CC(=O)NC1=CC=C(C=C1)OC
3-Hydroxy-2',4'-dimethyl-2-naphthanilide 98.0+%, TCI America™
CAS: 92-75-1 Molecular Formula: C19H17NO2 Molecular Weight (g/mol): 291.35 MDL Number: MFCD00021633 InChI Key: VTPSNRIENVXKCI-UHFFFAOYSA-N Synonym: 2-Hydroxy-3-naphthoic Acid m-Xylidide, Naphthol AS-MX, Azoic Coupling Component 29, 3-Hydroxy-N-(2′C,4′C-dimethylphenyl)-2-naphthamide PubChem CID: 66717 IUPAC Name: N-(2,4-dimethylphenyl)-3-hydroxynaphthalene-2-carboxamide SMILES: CC1=CC=C(NC(=O)C2=C(O)C=C3C=CC=CC3=C2)C(C)=C1
4-Acetamidobenzenethiol 90.0+%, TCI America™
CAS: 1126-81-4 Molecular Formula: C8H9NOS Molecular Weight (g/mol): 167.23 MDL Number: MFCD00004848 InChI Key: AYEQJLOHMLYKAV-UHFFFAOYSA-N Synonym: 4-acetamidothiophenol,4'-mercaptoacetanilide,4-acetamidobenzenethiol,n-4-sulfanylphenyl acetamide,4-acetamido thiophenol,n-4-mercaptophenyl acetamide,acetanilide, 4'-mercapto,4-acetaminothiophenol,4-mercaptoacetanilide,4-acetylaminothiophenol PubChem CID: 70777 IUPAC Name: N-(4-sulfanylphenyl)acetamide SMILES: CC(=O)NC1=CC=C(S)C=C1