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Filtered Search Results
eMolecules 935534-49-9 | Methyl 3-bromo-2,4-difluorobenzoate | Apollo Scientific | MFCD09261258 | 251.027 | C8H5BrF2O2 | 95.000 | COC(=O)c1ccc(F)c(Br)c1F | 1g | 562436614
Methyl 3-bromo-2,4-difluorobenzoate | Apollo Scientific | 935534-49-9 | MFCD09261258 | 251.027 | C8H5BrF2O2 | 95.000 | COC(=O)c1ccc(F)c(Br)c1F | 1g | 562436614
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eMolecules 2168525-92-4 | Medchem Express | UT-34 | 5mg | 649421650 | HY-136242 | 356.281 | C15H12F4N4O2
Ambeed | 3-Fluorobenzamide | 5g | 552745615 | A589418 | 455-37-8 | MFCD00007983 | 139.129 | C7H6FNO
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Medchemexpress LLC IK1 inhibitor PA-6 | 500715-03-7 | 99.3% | 492.61 | 50 MG
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IK1 inhibitor PA-6, a pentamidine analogue, is a selective and potent IK1 (KIR2.x ion-channel-carried inward rectifier current) inhibitor. It has IC50 values of 12-15 nM for human and mouse KIR2.x currents and elevates KIR2.1 protein expression, inducing intracellular KIR2.1 accumulation. This inhibitor has the potential to treat atrial fibrillation and arrhythmia.
- Selective and potent IK1 inhibitor
- IC50 values of 12-15 nM for human and mouse KIR2.x currents
- Elevates KIR2.1 protein expression
- Induces intracellular KIR2.1 accumulation
- Potential to treat atrial fibrillation
- Potential to treat arrhythmia
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Medchemexpress LLC Brivanib | 649735-46-6 | MFCD13194684 | >98.0% | 370.38 g/mol | C19H19FN4O3 | 10 MG
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Brivanib is an ATP-competitive small-molecule inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2) with an IC50 of 25 nM. It displays moderate activity against VEGFR-1 and FGFR-1 and is highly selective versus PDGFR-β. Supplied for research and analytical use, the compound is provided as a powder with specified storage recommendations.
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Medchemexpress LLC BSJ-02-162 (CDK4/6-IN-11) | 2139329-47-6 | 98.1% | C43H49N11O7 | 50 MG
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CDK4/6-IN-11 is a potent PROTAC CDK4/6 degrader. It is composed of a thalidomide-based E3 ligase ligand, a target protein ligand (Palbociclib), and a PROTAC linker. The E3 ligase ligand and linker can combine to form Thalidomide-NH-amido-C4-Br. The product is intended for research use only.
- Potent PROTAC CDK4/6 degrader, effectively degrades CDK4/6.
- Composed of well-defined components including a thalidomide-based E3 ligase ligand, Palbociclib as a target protein ligand, and a PROTAC linker.
- High purity of 98.07% ensures reliable experimental results.
- Available in various quantities, ranging from 5 mg to 500 mg, catering to different research needs.
- Detailed documentation including Data Sheet, SDS, COA, HNMR, RP-HPLC, MS, and Handling Instructions are available.
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Medchemexpress LLC Parsaclisib hydrochloride | 1995889-48-9 | 99.3% | 469.34 | 1 MG
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Parsaclisib hydrochloride is a potent, selective, and orally active inhibitor of PI3Kδ, with an IC50 of 1 nM at 1 mM ATP. It exhibits approximately 20000-fold selectivity over other PI3K class I isoforms and is used for the research of relapsed or refractory B-cell malignancies.
- Potent, selective, and orally active inhibitor of PI3Kδ
- High potency and selectivity for PI3Kδ
- Used for research of relapsed or refractory B-cell malignancies
- Inhibits proliferation of MCL and DLBCL cell lines
- Inhibits tumor growth in BALB/c mice bearing A20 murine lymphoma cells
- Potential therapeutic agent for B-cell malignancies
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Medchemexpress LLC HY-10367 50mg Medchemexpress, Canertinib CAS:267243-28-7 Purity:>98%
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Medchemexpress, HY-10367 50mg Canertinib CAS:267243-28-7 Canertinib (CI-1033;PD-183805) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-19366 5mg Medchemexpress, Nav1.7-IN-2 CAS:1332295-35-8 Purity:>98%
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Medchemexpress, HY-19366 5mg Nav1.7-IN-2 CAS:1332295-35-8 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 916423-52-4 | 3-(4-Fluorophenyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine | Oakwood Chemical | MFCD09258793 | 217.247 | C12H12FN3 | 0.000 | Fc1ccc(cc1)-c1[nH]nc2CCNCc12 | 100mg | 537693837
3-(4-Fluorophenyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine | Oakwood Chemical | 916423-52-4 | MFCD09258793 | 217.247 | C12H12FN3 | 0.000 | Fc1ccc(cc1)-c1[nH]nc2CCNCc12 | 100mg | 537693837
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Medchemexpress LLC HY-10617 200mg , Rucaparib (phosphate) AG-014699 phosphate;PF-01367338 phosphate CAS:459868-92-9 Purity:98%
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Medchemexpress, HY-10617 200mg Rucaparib (phosphate) AG-014699 phosphate;PF-01367338 phosphate CAS:459868-92-9 Formula:C19H21FN3O5P Ki: 1.4 nM (PARP1) Purity:98% Rucaparib (phosphate) is an inhibitor of PARP with K i of 1.4 nM for PARP1 in a cell-free assay, and also shows binding affinity to eight other PARP domains. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Azd-8529 | 1092453-15-0 | MFCD31657360 | 98.0% | 487.47 g/mol | C24H24F3N5O3 | 5 MG
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AZD-8529 is a potent, selective, orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 2 (mGluR2) used in preclinical neuroscience and pharmacology research. The compound is provided with defined purity and physicochemical characterization to support reproducible in vitro and in vivo studies.
- Potent mGluR2 positive allosteric modulator.
- High selectivity for mGluR2 over related receptors.
- Orally bioavailable, suitable for in vivo studies.
- Provided with defined purity and molecular data for reproducibility.
- Available in small-quantity formats and DMSO solution for screening.
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eMolecules 1350653-20-1 | Medchem Express | Vericiguat | 2mg | 446267874 | HY-16774 | MFCD28502029 | 426.388 | C19H16F2N8O2
ChemScene | 2-Chloro-4-phenylnicotinonitrile | 1g | 572229471 | CS-W002867 | 163563-64-2 | MFCD01935958 | 214.650 | C12H7ClN2
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Cayman Chemical ANTIBODY DIapocynIn 5mg
An NADPH oxidase inhibitor with anti-inflammatory and antioxidant activities; inhibits NADPH oxidase complex assembly and activation, gp91phox mRNA expression, and production of the pro-inflammatory cytokines TNF-α and IL-10 in PMBCs; inhibits ROS production, iPLA2 function, and reduces Ca2+ influx through SOCs and SACs in dystrophic myotubes; reverses motor coordination deficits in the LRRK2R1441G mouse model of EArly Parkinson's disease
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eMolecules 2050747-49-2 | Medchem Express | P-gp inhibitor 1 | 5mg | 721309271 | HY-101791 | 517.633 | C32H31N5O2
Medchem Express | Istaroxime (hydrochloride) | 5mg | 446266427 | HY-15718A | 374559-48-5 | MFCD26960953 | 396.960 | C21H33ClN2O3
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eMolecules 2,6-Difluoromandelic acid | 207981-50-8 | MFCD00061298 | 1g
Matrix Scientific | 2,6-Difluoromandelic acid | 1g | 389714871 | 5298 | 97.000 | 207981-50-8 | MFCD00061298 | 188.130 | C8H6F2O3
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